公开(公告)号：DE60127455T2

公开(公告)日：2007-11-29

申请号：DE60127455

申请日：2001-12-25

Applicant: UBE INDUSTRIES

Inventor： HARADA KATSUMASA ,  NISHINO SHIGEYOSHI ,  HIROTSU KENJI ,  NAKAMURA AKIRA ,  HARADA TAKASHI

IPC: C07C255/17 ,  C07C253/30 ,  C07C255/31

Abstract: A process comprising reacting an aliphatic carboxylic ester compound with acetonitrile in the presence of a metal alkoxide to yield a metal salt of a beta -ketonitrile compound, subsequently transferring the salt to an aqueous medium, and neutralizing the solution to obtain the beta -ketonitrile compound in a free state, wherein a water-immisible organic solvent and water are added to the reaction mixture containing the beta -ketonitrile compound metal salt yielded to transfer the metal salt to the water, the resultant aqueous solution of the beta -keto-nitrile compound metal salt is separated from the organic solvent by phase separation or another technique and then neutralized, and the resultant free beta -ketonitrile compound is taken out by extraction with an organic solvent.

公开(公告)号：AT357429T

公开(公告)日：2007-04-15

申请号：AT01272314

申请日：2001-12-25

Applicant: UBE INDUSTRIES

Inventor： HARADA KATSUMASA ,  NISHINO SHIGEYOSHI ,  HIROTSU KENJI ,  NAKAMURA AKIRA ,  HARADA TAKASHI

IPC: C07C253/30 ,  C07C255/17 ,  C07C255/31

Abstract: A process comprising reacting an aliphatic carboxylic ester compound with acetonitrile in the presence of a metal alkoxide to yield a metal salt of a beta -ketonitrile compound, subsequently transferring the salt to an aqueous medium, and neutralizing the solution to obtain the beta -ketonitrile compound in a free state, wherein a water-immisible organic solvent and water are added to the reaction mixture containing the beta -ketonitrile compound metal salt yielded to transfer the metal salt to the water, the resultant aqueous solution of the beta -keto-nitrile compound metal salt is separated from the organic solvent by phase separation or another technique and then neutralized, and the resultant free beta -ketonitrile compound is taken out by extraction with an organic solvent.

公开(公告)号：CA1199534A

公开(公告)日：1986-01-21

申请号：CA406837

申请日：1982-07-07

Applicant: UBE INDUSTRIES

Inventor： MAKINO HIROSHI ,  KUSUKI YOSHIHIRO ,  HARADA TAKASHI ,  SHIMAZAKI HIROSHI ,  ISIDA TOSIO

IPC: B01D69/12 ,  B01D71/64 ,  C08L79/08 ,  B01D13/04

Abstract: AROMATIC POLYIMIDE COMPOSITE SEPARATING MEMBRANE An aromatic polyimide composite membrane having a satisfactory gas-permeating property and an excellent gasseparating property comprises an aromatic polyimide porous membrane substrate and at least one coating layer which has been prepared (A) by coating at least one surface of the substrate with a dilute dope solution containing 0.01 to 5 parts by weight of a soluble aromatic polyimide and/or polyamic acid dissolved in a solvent which consists essentially of 100 parts by weight of a base component incapable of dissolving therein the substrate in an amount of 3% by weight or more and 0 to 15 parts by weight of an additional component capable of dissolving therein the 5% by weight or more of the aromatic polymeric material and compatible with the base component; and (B) by gradually evaporating the solvent from the coated dilute dope solution layer.

公开(公告)号：GB2104905B

公开(公告)日：1984-11-07

申请号：GB8219407

申请日：1982-07-05

Applicant: UBE INDUSTRIES

Inventor： KUSUKI YOSHIHIRO ,  MAKINO HIROSHI ,  ISIDA TOSIO ,  SHINAZAKI HIROSHI ,  HARADA TAKASHI

IPC: B01D61/38 ,  B01D71/64 ,  B01D53/22 ,  C08G73/00 ,  C08G73/10 ,  C08J9/40 ,  C08L79/08

Abstract: An aromatic polyimide membrane having an excellent gas-separating property comprises (A) a substrate consisting of a porous membrane comprising at least one aromatic polyimide having at least 80 molar % of at least one type of recurring unit of the formula (I): (I) wherein R is a tetravalent aromatic radical and R1 is a divalent aromatic radical, the porous membrane exhibiting a hydrogen gas permeability (PH2) of 1x10-5 to 5x10-1 cm3/cm2.sec.cmHg and a ratio of hydrogen gas permeability (PH2) to carbon monoxide gas permeability (PCO) of 2 to 5; and (B) 50% or more, based on the weight of the porous membrane substrate, of a gas-separating liquid contained in the porous membrane substrate, the gas-separating liquid being substantially incapable of dissolving therein the porous membrane substrate and having a boiling point of 180 DEG C. or more.

公开(公告)号：GB2102334B

公开(公告)日：1984-10-31

申请号：GB8217147

申请日：1982-06-14

Applicant: UBE INDUSTRIES

Inventor： MAKINO HIROSHI ,  KUSUKI YOSHIHIRO ,  HARADA TAKASHI ,  SHIMAZAKI HIROSHI ,  ISIDA TOSIO

IPC: B32B5/18 ,  B01D53/22 ,  B01D69/12 ,  B01D71/64 ,  B05D7/04 ,  C08J9/28 ,  C08J5/18

Abstract: An aromatic polyimide composite membrane having an excellent gas-separating property is produced by a process comprising the steps of: coating at least one surface of a substrate consisting of an aromatic polyimide porous membrane with a solution of 0.05% to 10% by weight of an aromatic polyamic acid in a polar organic solvent, which is not capable of dissolving the polyimide porous membrane, at a temperature not exceeding 140 DEG C.; after a during drying the resultant thin coating layer of the polyamic acid solution, heating the resultant polyamic acid layer at a temperature of 150 DEG C. or more so as to convert the polyamic acid layer to the corresponding polyimide layer.

公开(公告)号：DE3213582A1

公开(公告)日：1983-02-17

申请号：DE3213582

申请日：1982-04-13

Applicant: UBE INDUSTRIES

Inventor： MAKINO HIROSHI ,  KUSUKI YOSHIHIRO ,  HARADA TAKASHI ,  SHIMAZAKI HIROSHI ,  ISIDA TOSIO

IPC: B01D53/22 ,  B01D71/62 ,  B01D71/64 ,  C08J9/04 ,  C08J9/28 ,  C08L79/08 ,  C08J5/18 ,  B01D13/04 ,  B01D59/12

Abstract: A porous membrane of an aromatic polyimide having an enhanced permeability of a gas or liquid is produced by a process comprising the steps of (1) preparing a dope solution of 3 to 30% by weight of an aromatic polyimide in a mixed solvent of (A) 100 parts by weight of a base solvent capable of dissolving 5% by weight or more of the polymeric acid and of evaporating at 30 DEG C. to 400 DEG C. and (B) 5 to 150 parts by weight of an additional liquid not capable of dissolving 3% by weight or more of the polyamic acid and capable of evaporating at a smaller evaporating rate than that of the base solvent at the above-mentioned evaporating temperature; (2) forming a thin layer of the dope solution at 0 DEG C. to 120 DEG C.; and (3) heating the dope solution layer at 30 DEG C. to 400 DEG C. so as to evaporate off the mixed solvent and to convert the polyamic acid to the corresponding polyimide.

公开(公告)号：AT533750T

公开(公告)日：2011-12-15

申请号：AT03703218

申请日：2003-02-06

Applicant: UBE INDUSTRIES

Inventor： NISHINO SHIGEYOSHI ,  HIROTSU KENJI ,  SHIMA HIDETAKA ,  HARADA TAKASHI ,  ODA HIROYUKI

IPC: C07D239/86 ,  C07D239/88 ,  C07D239/94

Abstract: Preparation of an optionally substituted 4-aminoquinazoline compound (III) involves: (i) reacting the corresponding quinazolin-4-one compound (I) with a chlorinating agent in a first organic solvent in the presence of an organic base; and (ii) reacting the product with ammonia or amine (II) in a second organic solvent. Preparation of a 4-aminoquinazoline compound of formula (III) involves: (i) reacting a quinazolin-4-one compound of formula (I) with a chlorinating agent in a first organic solvent in the presence of an organic base; and (ii) reacting the product with ammonia or amine of formula R 5>NHR 6>(II) in a second organic solvent. [Image] R 1>-R 4>group which is inert in the reaction conditions; and R 5>, R 6>H or substituent. An independent claim is also included for the preparation of 6-halo-4-chloroquinazoline of formula (VII) from 6-halo-quinazolin-4-one of formula (VI). [Image] X : halo; and Ar' : optionally substituted aryl.

公开(公告)号：ES2328029T3

公开(公告)日：2009-11-06

申请号：ES03703066

申请日：2003-01-28

Applicant: UBE INDUSTRIES

Inventor： NISHINO SHIGEYOSHI ,  HIROTSU KENJI ,  SHIMA HIDETAKA ,  HARADA TAKASHI ,  ODA HIROYUKI ,  TAKAHASHI TAKESHI

IPC: C07D239/88 ,  C07C201/08 ,  C07C205/59 ,  C07C205/60 ,  C07C227/04 ,  C07C229/56 ,  C07C229/64 ,  C07D239/90

Abstract: Un proceso para preparar un compuesto de quinazolin-4-ona que tiene la fórmula (2): en la cual cada uno de R 1 , R 2 , R 3 y R 4 representa independientemente un grupo que no participa en la reacción mencionada a continuación, que comprende hacer reaccionar un compuesto de ácido antranílico que tiene la fórmula (1): en la cual R 1 , R 2 , R 3 y R 4 tienen el mismo significado que anteriormente, y R 5 representa un átomo de hidrógeno o un grupo hidrocarbilo, con un derivado de ácido fórmico seleccionado del grupo constituido por ésteres de ácido fórmico y ésteres de ácido ortofórmico en presencia de un carboxilato alifático de amonio o un carboxilato aromático de amonio.

公开(公告)号：SK10812002A3

公开(公告)日：2003-03-04

申请号：SK10812002

申请日：2001-01-24

Applicant: UBE INDUSTRIES ,  NISSAN CHEMICAL IND LTD

Inventor： HARADA KATSUMASA ,  NISHINO SHIGEYOSHI ,  OKADA NAOKO ,  SHIMA HIDETAKA ,  HARADA TAKASHI

IPC: C07D215/12 ,  C07D215/14

Abstract: 3-Ä2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolylÜprop-2-enenitrite is prepared by reacting 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde with acetonitrile in the presence of a base and then adding a dehydrating to the reaction mixture to conduct dehydration. Under ordinary conditions, novel 3-Ä2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylÜ-3-hydroxypropionitrile is formed as an intermediate in the above reaction. Incidentally, when the above reaction is conducted in an organic solvent, 3-Ä2-cyclopropyl-4-(4-fluorophenyl)-3-quinolylÜ-prop-2-enenitrite is directly formed.

公开(公告)号：CA2398113A1

公开(公告)日：2001-07-26

申请号：CA2398113

申请日：2001-01-24

Applicant: UBE INDUSTRIES ,  NISSAN CHEMICAL IND LTD

Inventor： HARADA TAKASHI ,  HARADA KATSUMASA ,  NISHINO SHIGEYOSHI ,  OKADA NAOKO ,  SHIMA HIDETAKA

IPC: C07D215/12 ,  C07D215/14

Abstract: 3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]prop-2-enenitrile is prepared by reacting 2-cyclopropyl-4- (4-fluorophenyl)quinoline-3-carbaldehyde with acetonitrile in the presence of a base and then adding a dehydrating agent t o the reaction mixture to conduct dehydration. Under ordinary conditions, nove l 3-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3-hydroxypropionitrile is formed as an intermediate in the above reaction. Incidentally, when the abov e reaction is conducted in an organic solvent, 3-[2- cyclopropyl-4-(4- fluorophenyl)-3-quinolyl]prop-2-enenitrile is directly formed.