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公开(公告)号:CL2023001509A1
公开(公告)日:2024-01-19
申请号:CL2023001509
申请日:2023-05-25
Applicant: UCB BIOPHARMA SRL
Inventor: RALPH ADAMS , JOSEPH MICHAEL DAVID RASTRICK , JOHN PAUL SILVA , KERRY LOUISE TYSON , PETER CHARLES ELLIOTT , SEPPE FRANS ROMAN LEYSEN , ZAINAB AHDASH , DANIEL JOHN LIGHTWOOD , ROGER THOMAS PALFRAMAN , SEEMA MAYANK , ANDREA JULIE CROSBY , EMILY MARY CAIRISTINE BARRY
IPC: C07K16/24
Abstract: La presente invención se refiere a anticuerpos que se unen a IL13 e IL22. La invención proporciona nuevos anticuerpos multiespecíficos que se unen tanto a IL13 como a IL22 y a composiciones que comprenden un anticuerpo que se une a IL13 y un anticuerpo que se une a IL22. La invención se refiere además a usos terapéuticos de la combinación de anticuerpos anti-IL13 y anti-IL22 y anticuerpos multi-específicos que se unen tanto a IL13 como a IL22.
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公开(公告)号:ZA202305329B
公开(公告)日:2024-09-25
申请号:ZA202305329
申请日:2023-05-16
Applicant: UCB BIOPHARMA SRL
Inventor: JOSEPH MICHAEL DAVID RASTRICK , JOHN PAUL SILVA , DANIEL JOHN LIGHTWOOD , RALPH ADAMS , ROGER THOMAS PALFRAMAN , KERRY LOUISE TYSON , PETER CHARLES ELLIOTT , SEEMA MAYANK , ANDREA JULIE CROSBY , EMILY MARY CAIRISTINE BARRY , SEPPE FRANS ROMAN LEYSEN , ZAINAB AHDASH
Abstract: The present invention relates to antibodies binding to IL13 and IL22. The invention provides novel multi-specific antibodies that bind to both IL13 and IL22 and compositions comprising an antibody that binds to IL13 and an antibody that binds to IL22. The invention further relates to therapeutic uses of the combination of anti-IL13 and anti-IL22 antibodies and multi-specific antibodies that bind to both IL13 and IL22.
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