公开(公告)号：US6362367B2

公开(公告)日：2002-03-26

申请号：US6367598

申请日：1998-04-21

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVID ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C51/21

CPC classification number: C07C51/265 ,  B01J19/006 ,  B01J19/0066 ,  B01J19/0073 ,  B01J19/1875 ,  B01J2219/00058 ,  B01J2219/00085 ,  B01J2219/00763 ,  B01J2219/00774 ,  B01J2219/00779 ,  C07C51/235 ,  Y02P20/149 ,  Y02P20/582

Abstract: This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

Abstract translation: 本发明涉及一种制备高纯度的一种或多种有机酸的方法，该方法包括（i）在液体氧化反应器中氧化具有至少约50％氧气的基本上纯氧或富氧空气的一种或多种有机液体， 在足够稳定的温度下以防止反应速率的循环，以产生粗反应产物流体，和（ii）精制所述粗反应产物流体以产生高纯度的所述一种或多种有机酸。 氧化温度优选控制在目标温度的约±3℃内。 本文所述的有机酸可用于各种应用，例如化学化合物的制造中的中间体，药物制造等。

公开(公告)号：BR9909798A

公开(公告)日：2000-12-26

申请号：BR9909798

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVIS ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C53/02 ,  C07C53/08 ,  C07C53/122 ,  C07C53/124 ,  C07C55/14 ,  C07C57/32 ,  C07C57/30 ,  C07C63/06 ,  C07C63/16 ,  C07C63/24 ,  C07C63/26 ,  C07C59/64

Abstract: This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

公开(公告)号：AU3657199A

公开(公告)日：1999-11-08

申请号：AU3657199

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVID ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C53/02 ,  C07C53/08 ,  C07C53/122 ,  C07C53/124 ,  C07C55/14 ,  C07C57/32 ,  C07C57/30 ,  C07C63/06 ,  C07C63/16 ,  C07C63/24 ,  C07C63/26 ,  C07C59/64

Abstract: This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

公开(公告)号：ES2247797T3

公开(公告)日：2006-03-01

申请号：ES99918722

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVID ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C53/02 ,  C07C53/08 ,  C07C53/122 ,  C07C53/124 ,  C07C55/14 ,  C07C57/32 ,  C07C57/30 ,  C07C63/06 ,  C07C63/16 ,  C07C63/24 ,  C07C63/26 ,  C07C59/64

Abstract: Un procedimiento para producir al menos un ácido orgánico de elevada pureza, procedimiento que comprende oxidar, en un reactor de oxidación para líquidos, al menos un líquido orgánico con oxígeno esencialmente puro o aire enriquecido en oxígeno que contiene al menos 50% de oxígeno para producir un producto de reacción bruto fluido, y refinar dicho producto de reacción bruto fluido para proporcionar al menos dicho ácido orgánico de elevada pureza, en el que dicho reactor de oxidación para líquidos comprende: a) una vasija del reactor tubular verticalmente posicionada que tiene un tubo hueco de aspiración en su centro y tubos de intercambio de calor en el espacio anular entre el tubo hueco de aspiración y la pared exterior de la vasija del reactor, teniendo dicha vasija del reactor un espacio superior por encima y una cámara de mezcla hueca por debajo de dicho tubo hueco de aspiración y dichos tubos de intercambio de calor; b) medios impulsores posicionados dentro de dicho tubo hueco de aspiración y adaptados para provocar el flujo rápido del líquido orgánico hacia abajo a través del tubo hueco de aspiración hacia la cámara de mezcla inferior y rápidamente hacia arriba a través de dichos tubos de intercambio de calor como una dispersión sustancialmente uniforme y hacia dicho espacio superior en la vasija del reactor; c) una cámara superior posicionada por encima de y en comunicación fluida con dicha vasija del reactor, teniendo dicha cámara superior un espacio de vapor por encima de un nivel de líquido deseado; d) al menos un deflector de confinamiento de gas generalmente horizontal dispuesto entre dicha cámara superior y dicha vasija de reacción de tal forma que el espacio de vapor por encima del nivel de líquido en dicha cámara superior se mantiene por debajo tanto de LOV y LFL, estando formado dicho deflector de confinamiento de gas por un agujero central para permitir que dichos medios de impulsión se extiendan generalmente concéntricamente a través de dicho agujero en dicho deflector de confinamiento de gas.

公开(公告)号：ID29050A

公开(公告)日：2001-07-26

申请号：ID20002092

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVID ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C53/02 ,  C07C53/08 ,  C07C53/122 ,  C07C53/124 ,  C07C55/14 ,  C07C57/32 ,  C07C57/30 ,  C07C63/06 ,  C07C63/16 ,  C07C63/24 ,  C07C63/26 ,  C07C59/64

Abstract: This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

公开(公告)号：AT307106T

公开(公告)日：2005-11-15

申请号：AT99918722

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVID ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C53/02 ,  C07C53/08 ,  C07C53/122 ,  C07C53/124

Abstract: This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

公开(公告)号：PL343605A1

公开(公告)日：2001-08-27

申请号：PL34360599

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： BRAITHWAITE JOHN ,  BRYANT DAVID ROBERT ,  MILLER DAVID JAMES ,  LOGSDON JOHN EARL

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126

Abstract: This invention relates to a process for producing one or more organic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen-enriched air containing at least about 50% oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperature is preferably controlled to within about ±3° C. of a target temperature. The organic acids described herein is useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.

公开(公告)号：CA2329309A1

公开(公告)日：1999-10-28

申请号：CA2329309

申请日：1999-04-20

Applicant: UNION CARBIDE CHEM PLASTIC

Inventor： LOGSDON JOHN EARL ,  BRAITHWAITE JOHN ,  MILLER DAVID JAMES ,  BRYANT DAVID ROBERT

IPC: B01J10/00 ,  B01J19/00 ,  B01J19/18 ,  B01J19/20 ,  C07C51/235 ,  C07C51/265 ,  C07C53/126 ,  C07C53/02 ,  C07C63/06 ,  C07C53/08 ,  C07C53/122 ,  C07C53/124 ,  C07C55/14 ,  C07C63/16 ,  C07C63/24 ,  C07C63/26 ,  C07C57/30 ,  C07C57/32 ,  C07C59/64

Abstract: This invention relates to a process for producing one or more org anic acids in high purity which process comprises (i) oxidizing in a liquid oxidation reactor one or more organic liquids with essentially pure oxygen or oxygen- enriched air containing at least about 50 % oxygen, at a temperature sufficiently stable to prevent cycling of reaction rate, to produce a crude reaction product fluid, and (ii) refining said crude reaction product fluid to give said one or more organic acids in high purity. The oxidation temperatur e is preferably controlled to within about ~3 ~C of a target temperature. The organic acids described herein are useful in a variety of applications, such as intermediates in the manufacture of chemical compounds, pharmaceutical manufacture and the like.