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公开(公告)号：US10031106B2
公开(公告)日：2018-07-24
申请号：US14646816
申请日：2013-11-19
Applicant: UNIVERSITEIT TWENTE
Inventor： Sebastiaan Waanders , Martijn Visscher , Tasio Olmo Borendissi Oderkerk , Hendrikus Johannes Gradus Krooshoop , Bernard Haken
Abstract: Method and apparatus for measuring an amount of superparamagnetic material in an object, the method including a) applying a magnetic field having a first component alternating with a first period to the object and a magnetic field strength lower than a magnetic field strength at which the superparamagnetic material is driven in saturation; b) measuring a first magnetic susceptibility of the object with a detection coil; c) applying a static second component to the magnetic field for a second period being equal or larger than the first period, the strength of the magnetic field during the second period is such that the superparamagnetic material is driven towards saturation; d) measuring a second magnetic susceptibility of the object with the detection coil during the application of the static second component; and e) determining the amount of superparamagnetic material from a difference between the measured first and second susceptibility of the object.
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公开(公告)号：US12196827B2
公开(公告)日：2025-01-14
申请号：US18000514
申请日：2021-06-02
Applicant: Universiteit Twente
Inventor： Melissa Mathilde van de Loosdrecht , Hendrikus Johannes Gradus Krooshoop , Bernard ten Haken , Lejla Alic
Abstract: The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.
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公开(公告)号：US20230236269A1
公开(公告)日：2023-07-27
申请号：US18000514
申请日：2021-06-02
Applicant: Universiteit Twente
Inventor： Melissa Mathilde van de Loosdrecht , Hendrikus Johannes Gradus Krooshoop , Bernard ten Haken , Lejla Alic
CPC classification number: G01R33/1276 , A61B5/062
Abstract: The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.
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