公开(公告)号：US20160355582A1

公开(公告)日：2016-12-08

申请号：US15089285

申请日：2016-04-01

Applicant: UNIVERSITEIT TWENTE

Inventor： Hermanus Bernardus Johannes KARPERIEN ,  Cornelis Theodorus VERRIPS ,  Mohamed EL KHATTABI ,  Emilie DOOMS RODRIGUES ,  Jan DE BOER ,  Clemens Antoni VAN BLITTERSWIJK ,  Renee DE BRUIN

IPC: C07K16/22 ,  C07K16/44

CPC classification number: C07K16/22 ,  A61L27/227 ,  A61L27/54 ,  A61L31/047 ,  A61L31/16 ,  A61L2300/25 ,  A61L2300/432 ,  C07K16/18 ,  C07K16/44 ,  C07K2317/22 ,  C07K2317/41 ,  C07K2317/569 ,  C07K2319/01

Abstract: The present invention relates to a VHH which binds to a growth factor or is an antagonist for a growth factor, or binds to an implant.

Abstract translation: 本发明涉及与生长因子结合或是生长因子的拮抗剂或与植入物结合的VHH。

公开(公告)号：US20200298563A1

公开(公告)日：2020-09-24

申请号：US16088116

申请日：2017-03-29

Applicant: UNIVERSITEIT TWENTE

Inventor： Claas Willem Visser ,  Tom KAMPERMAN ,  Hermanus Bernardus Johannes KARPERIEN ,  Detlef LOHSE

IPC: B41J2/14 ,  B01J13/08 ,  B01J13/14

Abstract: A production process and a related device comprises a formation process comprising: contacting a first liquid material and a second liquid material with each other at a contact point in a gas atmosphere, wherein at the contact point at least one of the first liquid material and the second liquid material is provided as a liquid jet propagating in a direction, to provide at the contact point a third jet of a coalesced third material propagating in a third direction.

公开(公告)号：US20160096920A1

公开(公告)日：2016-04-07

申请号：US14890982

申请日：2014-05-16

Applicant: UNIVERSITEIT TWENTE

Inventor： Jasper VAN WEERD ,  Hermanus Bernardus Johannes KARPERIEN ,  Pascal JONKHEIJM

IPC: C08G63/91

CPC classification number: B32B27/06 ,  A61L27/18 ,  A61L27/34 ,  A61L27/54 ,  B32B15/04 ,  B32B17/06 ,  B32B18/00 ,  B32B27/36 ,  C08G63/912 ,  C08G63/916

Abstract: A process for the preparation of an object, supporting a lipid bilayer, for use in tissue engineering including the steps of providing an object having a surface, treating the surface of the object with a plasma containing active oxygen to provide the surface of the object with reactive groups A, to provide the surface of the object with reactive groups A, covalently attaching a sterol group to the reactive groups A and contacting the object activated with sterol groups with a lipid solution to form a lipid bilayer.

Abstract translation: 一种用于制备用于组织工程中的用于构成脂质双层的物体的方法，包括提供具有表面的物体的步骤，用含有活性氧的等离子体处理物体的表面以提供物体的表面 反应性基团A，以提供反应性基团A的表面，将甾醇基团共价连接到反应性基团A上，并将与甾醇基团活化的物质与脂质溶液接触以形成脂质双层。