公开(公告)号：US09550345B2

公开(公告)日：2017-01-24

申请号：US14890982

申请日：2014-05-16

Applicant: UNIVERSITEIT TWENTE

Inventor： Jasper Van Weerd ,  Hermanus Bernardus Johannes Karperien ,  Pascal Jonkheijm

IPC: B32B27/06 ,  B32B17/06 ,  B32B15/04 ,  B32B18/00 ,  B32B27/36 ,  A61L27/18 ,  A61L27/34 ,  A61L27/54 ,  C08G63/91

CPC classification number: B32B27/06 ,  A61L27/18 ,  A61L27/34 ,  A61L27/54 ,  B32B15/04 ,  B32B17/06 ,  B32B18/00 ,  B32B27/36 ,  C08G63/912 ,  C08G63/916

Abstract: A process for the preparation of an object, supporting a lipid bilayer, for use in tissue engineering including the steps of providing an object having a surface, treating the surface of the object with a plasma containing active oxygen to provide the surface of the object with reactive groups A, to provide the surface of the object with reactive groups A, covalently attaching a sterol group to the reactive groups A and contacting the object activated with sterol groups with a lipid solution to form a lipid bilayer.

Abstract translation: 一种用于制备用于组织工程中的用于构成脂质双层的物体的方法，包括提供具有表面的物体的步骤，用含有活性氧的等离子体处理物体的表面以提供物体的表面 反应性基团A，以提供反应性基团A的表面，将甾醇基团共价连接到反应性基团A上，并将与甾醇基团活化的物质与脂质溶液接触以形成脂质双层。