公开(公告)号：WO2015132672A2

公开(公告)日：2015-09-11

申请号：PCT/IB2015/000996

申请日：2015-03-06

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： BLASER, Heiko ,  MAK, Tak, W.

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  A61K38/177 ,  A61K39/39541 ,  A61K39/39558 ,  A61K49/0008 ,  A61K2039/505 ,  A61K2039/507 ,  C07K14/70503 ,  C07K16/2818 ,  C07K2317/76 ,  C12N15/1135 ,  C12N15/1138 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2320/30 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N33/5088 ,  G01N2333/82 ,  A61K2300/00

Abstract: The present invention is further directed to methods and compositions for identifying target nucleic acids that are involved in cancer metastasis.

Abstract translation: 本发明还涉及用于鉴定参与癌症转移的靶核酸的方法和组合物。

公开(公告)号：WO2016127247A1

公开(公告)日：2016-08-18

申请号：PCT/CA2016/000036

申请日：2016-02-11

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： BLASER, Heiko ,  MAK, Tak

IPC: A61K39/395 ,  A61K31/7088 ,  A61P35/04 ,  C07K16/28 ,  C12N15/113 ,  G01N33/53 ,  G01N33/574

CPC classification number: C07K16/2803 ,  A61K31/7088 ,  A61P35/04 ,  C07K16/30 ,  C07K2317/76 ,  C12N15/1138 ,  C12N2310/14 ,  C12N2310/3515 ,  G01N33/574 ,  G01N33/57423 ,  G01N2333/70503

Abstract: The present invention is directed to methods and compositions for modulating LILR for treatment of cancer and inhibition of metastasis.

Abstract translation: 本发明涉及用于调节LILR治疗癌症和抑制转移的方法和组合物。

公开(公告)号：EP3256163A1

公开(公告)日：2017-12-20

申请号：EP16748508.5

申请日：2016-02-11

Applicant: University Health Network

Inventor： BLASER, Heiko ,  MAK, Tak

IPC: A61K39/395 ,  A61K31/7088 ,  A61P35/04 ,  C07K16/28 ,  C12N15/113 ,  G01N33/53 ,  G01N33/574

CPC classification number: C07K16/2803 ,  A61K31/7088 ,  A61P35/04 ,  C07K16/30 ,  C07K2317/76 ,  C12N15/1138 ,  C12N2310/14 ,  C12N2310/3515 ,  G01N33/574 ,  G01N33/57423 ,  G01N2333/70503

Abstract: The present invention is directed to methods and compositions for modulating LILR for treatment of cancer and inhibition of metastasis.