公开(公告)号：WO2023283732A1

公开(公告)日：2023-01-19

申请号：PCT/CA2022/051087

申请日：2022-07-12

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： ZHENG, Gang ,  CHEN, Juan ,  HO, Tiffany ,  BU, Jiachuan ,  DING, Lili

IPC: A61K47/54 ,  A61K9/51 ,  A61K41/00 ,  A61K47/69 ,  A61K49/00 ,  A61K51/04 ,  A61K51/12

Abstract: There is described herein a bilayer nanovesicle comprising porphyrin-phospholipid conjugate and a chelator-fatty acid conjugate; wherein the chelator-fatty acid conjugate comprises an aminopolycarboxylic acid conjugated to a single chain fatty acid; and the porphyrin-phospholipid conjugate comprises one porphyrin, porphyrin derivative or porphyrin analog covalently attached to a lipid side chain, preferably at the sn-1 or the sn-2 position, of one phospholipid.

公开(公告)号：EP4370158A1

公开(公告)日：2024-05-22

申请号：EP22840900.9

申请日：2022-07-12

Applicant: University Health Network

Inventor： ZHENG, Gang ,  CHEN, Juan ,  HO, Tiffany ,  BU, Jiachuan ,  DING, Lili

IPC: A61K47/54 ,  A61K9/51 ,  A61K41/00 ,  A61K47/69 ,  A61K49/00 ,  A61K51/04 ,  A61K51/12

CPC classification number: A61K41/0071 ,  A61K47/544 ,  A61K47/6911 ,  A61K49/0036 ,  A61K49/0084 ,  A61K49/0002 ,  A61K49/227 ,  A61K51/1234 ,  A61K9/5123

公开(公告)号：EP3965833A1

公开(公告)日：2022-03-16

申请号：EP20802974.4

申请日：2020-05-06

Applicant: University Health Network

Inventor： ZHENG, Gang ,  CHEN, Juan ,  HOU, Wenxiu ,  BU, Jiachuan

IPC: A61K49/00 ,  A61K31/337 ,  A61K41/00 ,  A61K47/44 ,  A61K9/107 ,  A61K9/14 ,  C07D305/14 ,  C07D487/22