公开(公告)号：WO2018132890A1

公开(公告)日：2018-07-26

申请号：PCT/CA2017/000274

申请日：2017-12-21

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： St. PAUL, Michael ,  OHASHI, Pam ,  SAIBIL, Sam

IPC: C12N5/0783 ,  A61K31/7076 ,  A61K35/17 ,  A61P1/00 ,  A61P35/00 ,  C07H19/20 ,  C07K14/525 ,  C07K14/54 ,  C07K16/22 ,  C07K16/28

Abstract: There is described herein, a method for inducing Tc22 lineage T cells from a population of CD8+ T cells, the method comprising: a) providing a population of CD8+ T cells; b) activating the population; and c) culturing or contacting the population of CD8+ T cells with Coenzyme A.

公开(公告)号：WO2018132889A1

公开(公告)日：2018-07-26

申请号：PCT/CA2017/000270

申请日：2017-12-19

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： St. PAUL, Michael ,  OHASHI, Pamela S.

IPC: C12N5/0783 ,  A61K35/17 ,  A61P35/00 ,  C07K14/54 ,  C07K16/22 ,  C07K16/24 ,  C07K16/28

Abstract: There is described herein a method for inducing Tc22 lineage T cells from a population of CD8+ T cells, the method comprising: a) providing a population of CD8+ T cells; b) activating the population of CD8+ T cells; and c) culturing or contacting the population of CD8+ T cells with IL-6.