公开(公告)号：WO1997024363A1

公开(公告)日：1997-07-10

申请号：PCT/US1996020840

申请日：1996-12-26

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  BELARDINELLI, Luiz ,  OLSSON, Ray ,  BAKER, Stephen ,  SCAMMELLS, Peter, J. ,  MILNER, Peter, G. ,  PFISTER, Jurg, R.

IPC: C07H19/16

CPC classification number: C07H19/16 ,  C07D473/06 ,  Y10S514/821

Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.

Abstract translation: 腺苷和黄嘌呤衍生物以及包含这些化合物的组合物是腺苷受体的有效选择性激动剂和拮抗剂。 衍生物和组合物用于治疗包括某些心律失常的病症。

公开(公告)号：WO1995011904A1

公开(公告)日：1995-05-04

申请号：PCT/US1994012388

申请日：1994-10-28

Applicant: UNIVERSITY OF FLORIDA

Inventor： UNIVERSITY OF FLORIDA ,  BELARDINELLI, Luiz ,  OLSSON, Ray ,  BAKER, Stephen ,  SCAMMELLS, Peter, J. ,  MILNER, Peter, Gerard ,  PFISTER, Jurg, Roland ,  SCHREINER, George, Frederic

IPC: C07D473/08

CPC classification number: C07H19/16 ,  C07D473/06

Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.

Abstract translation: 腺苷和黄嘌呤衍生物以及包含这些化合物的组合物是腺苷受体的有效选择性激动剂和拮抗剂。 衍生物和组合物用于治疗包括某些心律失常的病症。

公开(公告)号：EP0725782B1

公开(公告)日：1999-12-15

申请号：EP95901070.3

申请日：1994-10-28

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： BELARDINELLI, Luiz ,  OLSSON, Ray ,  BAKER, Stephen ,  SCAMMELLS, Peter, J. ,  MILNER, Peter, Gerard ,  PFISTER, Jurg, Roland ,  SCHREINER, George, Frederic

IPC: C07D473/08 ,  C07H19/167 ,  C07D519/00 ,  A61K31/52

CPC classification number: C07H19/16 ,  C07D473/06

Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.

公开(公告)号：EP1019426B1

公开(公告)日：2003-03-12

申请号：EP96945316.6

申请日：1996-12-26

Applicant: University of Florida Research Foundation, Incorporated

Inventor： BELARDINELLI, Luiz ,  OLSSON, Ray ,  BAKER, Stephen ,  SCAMMELLS, Peter, J. ,  MILNER, Peter, G. ,  PFISTER, Jurg, R.

IPC: C07H19/16 ,  A61K31/70

CPC classification number: C07H19/16 ,  C07D473/06 ,  Y10S514/821

Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.

公开(公告)号：EP1019426A1

公开(公告)日：2000-07-19

申请号：EP96945316.6

申请日：1996-12-26

Applicant: THE UNIVERSITY OF FLORIDA

Inventor： BELARDINELLI, Luiz ,  OLSSON, Ray ,  BAKER, Stephen ,  SCAMMELLS, Peter, J. ,  MILNER, Peter, G. ,  PFISTER, Jurg, R.

IPC: C07H19/16 ,  A61K31/70

CPC classification number: C07H19/16 ,  C07D473/06 ,  Y10S514/821

Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.

公开(公告)号：EP0725782A1

公开(公告)日：1996-08-14

申请号：EP95901070.0

申请日：1994-10-28

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： BELARDINELLI, Luiz ,  OLSSON, Ray ,  BAKER, Stephen ,  SCAMMELLS, Peter, J. ,  MILNER, Peter, Gerard ,  PFISTER, Jurg, Roland ,  SCHREINER, George, Frederic

IPC: A61K31 ,  A61P1 ,  A61P3 ,  A61P9 ,  A61P11 ,  A61P13 ,  A61P43 ,  C07D473 ,  C07D519 ,  C07H19

CPC classification number: C07H19/16 ,  C07D473/06

Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.