公开(公告)号：US20150027873A1

公开(公告)日：2015-01-29

申请号：US14308117

申请日：2014-06-18

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： Ognjen Miljanic ,  Qing Ji

IPC: B01D3/34

CPC classification number: B01D3/34 ,  B01D3/009 ,  B01J2219/00599 ,  B01J2219/0072 ,  B01J2219/00759 ,  C07C67/02 ,  C40B40/04 ,  C40B50/04 ,  Y02P20/127 ,  C07C69/14 ,  C07C69/24 ,  C07C69/78

Abstract: An iterative method of performing a reactive distillation of dynamic ester libraries containing n×m (m≦n) components, to reduce such mixtures to n pure ester species. The distillation occurs under anhydrous conditions, using metal alkoxide catalysts. Vacuum distillation of the mixture then isolates the most volatile ester at the expense of other (2n−2) compounds. The volatile ester is removed, and the process repeated with progressively less volatile ester species, yielding high purities and greater than 70% yields.

Abstract translation: 对含有n×m（m＆nlE; n）组分的动态酯文库进行反应蒸馏的迭代方法，以将这种混合物还原成纯的酯类。 蒸馏在无水条件下使用金属醇盐催化剂进行。 混合物的真空蒸馏然后以其他（2n-2）化合物为代价分离最易挥发的酯。 除去挥发性酯，并且该方法用逐渐变少的挥发性酯物质重复，产生高纯度和大于70％产率。

公开(公告)号：US10138192B2

公开(公告)日：2018-11-27

申请号：US15559817

申请日：2016-03-17

Applicant: University of Houston System

Inventor： Ognjen Miljanic ,  Qing Ji

IPC: C07C45/45 ,  C07C15/00 ,  C07C45/44 ,  C07C49/727 ,  C07C15/50 ,  C07C47/544 ,  C07C49/215 ,  C07C49/245

Abstract: One-step cyanide-catalyzed benzoin condensations for synthesizing shape persistent cyclobenzoin macrocycles. Selected dialdehydes, and cyanide salts are reacted in aqueous solvents to form such cyclobenzoin macrocycles.