公开(公告)号：WO2023014666A1

公开(公告)日：2023-02-09

申请号：PCT/US2022/039079

申请日：2022-08-01

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： UDUGAMASOORIYA, Damith, Gomika ,  SHUKLA, Satya, Prakash ,  ZHANG, Haowen

IPC: C07K7/06 ,  C07K7/08 ,  A61K38/00 ,  A61P35/00 ,  G01N33/574

Abstract: Embodiments of the present disclosure pertains to one or more novel peptoids, derivatives thereof, multimers thereof, and combinations thereof. The peptoids may be suitable for use in treating or preventing a cancer in a subject, detecting a cancer in a subject, or as research and development tools. Further embodiments pertain to methods of inhibiting the growth of cancer cells by exposing the cancer cells to the peptoids. Additional embodiments of the present disclosure pertain to methods of treating or preventing a cancer in a subject by administering the peptoids to the subject. Further embodiments pertain to methods of detecting cancer in a subject by exposing cells susceptible of being cancerous to the peptoids, detecting the presence or absence of vimentin associated with cells susceptible of being cancerous, and correlating the presence or absence of the vimentin to the presence or absence of the cancer in the subject.

公开(公告)号：EP4380950A1

公开(公告)日：2024-06-12

申请号：EP22853776.7

申请日：2022-08-01

Applicant: University of Houston System

Inventor： UDUGAMASOORIYA, Damith, Gomika ,  SHUKLA, Satya, Prakash ,  ZHANG, Haowen

IPC: C07K7/06 ,  C07K7/08 ,  A61K38/00 ,  A61P35/00 ,  G01N33/574

CPC classification number: A61K38/00 ,  C07K7/08 ,  C07K7/06 ,  A61P35/00 ,  G01N33/574