公开(公告)号：US20150313976A1

公开(公告)日：2015-11-05

申请号：US14709877

申请日：2015-05-12

Applicant: University of Saskatchewan

Inventor： Scott Napper ,  Peter Hedlin ,  Philip Griebel ,  Lorne Babiuk ,  Neil Cashman ,  Avijit Chakrabartty ,  Andrew Potter

IPC: A61K39/00 ,  C07K14/47 ,  C07K7/08 ,  G01N33/68 ,  C07K7/06

CPC classification number: C07K14/47 ,  A61K39/0007 ,  A61K2039/6037 ,  C07K7/06 ,  C07K7/08 ,  C07K16/2872 ,  C07K2317/34 ,  G01N33/6893 ,  G01N33/6896 ,  G01N2333/705 ,  G01N2800/2828

Abstract: Prion peptides comprising prion epitopes and fusions thereof, that display enhanced immunogenicity are described. Also described are methods of treating and diagnosing prion disease.

Abstract translation: 描述了包含朊病毒表位和其融合物的朊病毒肽，其显示增强的免疫原性。 还描述了治疗和诊断朊病毒疾病的方法。

公开(公告)号：US09376476B2

公开(公告)日：2016-06-28

申请号：US14709877

申请日：2015-05-12

Applicant: University of Saskatchewan

Inventor： Scott Napper ,  Peter Hedlin ,  Philip Griebel ,  Lorne Babiuk ,  Neil Cashman ,  Avijit Chakrabartty ,  Andrew Potter

IPC: A61K39/00 ,  C07K14/47 ,  C07K7/06 ,  C07K7/08 ,  C07K16/28 ,  G01N33/68

CPC classification number: C07K14/47 ,  A61K39/0007 ,  A61K2039/6037 ,  C07K7/06 ,  C07K7/08 ,  C07K16/2872 ,  C07K2317/34 ,  G01N33/6893 ,  G01N33/6896 ,  G01N2333/705 ,  G01N2800/2828

Abstract: Prion peptides comprising prion epitopes and fusions thereof, that display enhanced immunogenicity are described. Also described are methods of treating and diagnosing prion disease.