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公开(公告)号：KR20180054858A
公开(公告)日：2018-05-24
申请号：KR20187012175
申请日：2016-09-30
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： BALINT BALAZS , KOTSCHY ANDRAS , SIPOS MELINDA , WEBER CSABA , FOLOPPE NICOLAS , WALMSLEY DAVID , BURBRIDGE MICHAEL FRANK , CRUZALEGUI FRANCISCO HUMBERTO
IPC: C07D471/04 , A61K31/437 , A61P25/00 , A61P25/16 , A61P25/28 , A61P35/00
CPC classification number: C07D471/04
Abstract: 암, 신경변성장애및 대사장애의치료에유용한하기화학식 (I)의화합물:(화학식 I)
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公开(公告)号：CA3027008C
公开(公告)日：2021-02-09
申请号：CA3027008
申请日：2017-06-09
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： KOTSCHY ANDRAS , WEBER CSABA , VASAS ATTILA , MOLNAR BALAZS , KISS ARPAD , MACIAS ALBA , MURRAY JAMES BROOKE , LEWKOWICZ ELODIE , GENESTE OLIVIER , CHANRION MAIA , DEMARLES DIDIER , IVANSCHITZ LISA
IPC: C07D471/04 , A61K31/519 , A61P35/00 , C07D487/04 , C07D495/04
Abstract: The present invention relates to (hetero)aryl-substituted-piperidinyl compounds of formula (I): (see formula I) wherein R1, R2, J, K, L, n and W are as defined herein. The invention also relates to a process for the preparation of said compound of formula (I), to pharmaceutical compositions containing them and their use in the field of apoptosis and oncology.
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3.发明专利
公开(公告)号：HUE049507T2
公开(公告)日：2020-09-28
申请号：HUE17727927
申请日：2017-06-09
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： KOTSCHY ANDRAS , WEBER CSABA , VASAS ATTILA , MOLNAR BALAZS , KISS ARPAD , MACIAS ALBA , MURRAY JAMES BROOKE , LEWKOWICZ ELODIE , GENESTE OLIVIER , CHANRION MAÎA , DEMARLES DIDIER
IPC: A61P35/00
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公开(公告)号：CA3116089A1
公开(公告)日：2020-04-23
申请号：CA3116089
申请日：2019-10-18
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： WEBER CSABA , KOTSCHY ANDRAS , VASAS ATTILA , KISS ARPAD , MOLNAR BALAZS , FIUMANA ANDREA , MACIAS ALBA , MURRAY JAMES BROOKE , DEMARLES DIDIER , IVANSCHITZ LISA , GENESTE OLIVIER , HEGEDUS KRISTOF , SPRANITZ PETER , SOOS TIBOR
IPC: C07D401/12 , A61K31/506 , A61P35/00 , C07D401/14 , C07D409/14 , C07D417/14
Abstract: Compounds of formula (I) wherein R1, R2, R3, R4, R5, n and Q are as defined in the description. Medicaments.
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公开(公告)号：ECSP21024078A
公开(公告)日：2021-05-31
申请号：ECDI202124078
申请日：2021-04-07
Applicant: VERNALIS R D LTD , SERVIER LAB
Inventor： SPRANITZ PETER , HEGEDÜS KRISTOF , MOLNAR BALAZS , MACIAS ALBA , DEMARLES DIDIER , WEBER CSABA , IVANSCHITZ LISA , KOTSCHY ANDRAS , FIUMANA ANDREA , MURRAY JAMES BROOKE , SOOS TIBOR , VASAS ATTILA , KISS ARPAD , GENESTE OLIVIER
IPC: A61K31/506 , A61P35/00
Abstract: Compuestos de fórmula (I): (VER FORMULA EN LA MEMORIA TECNICA) en donde R1, R2, R3, R4, R5, n y Q son como se definen en la descripción. Medicamentos.
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Patent Agency Ranking
公开(公告)号：SI3468971T1
公开(公告)日：2020-07-31
申请号：SI201730267
申请日：2017-06-09
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： LEWKOWICZ ELODIE , GENESTE OLIVIER , KOTSCHY ANDRAS , WEBER CSABA , VASAS ATTILA , MOLNAR BALAZS , KISS ARPAD , MACIAS ALBA , MURRAY JAMES BROOKE , CHANRION MAIA , DEMARLES DIDIER , IVANSCHITZ LISA
IPC: C07D471/00 , A61K31/00 , A61P35/00 , C07D487/00 , C07D495/00
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公开(公告)号：MD3468974T2
公开(公告)日：2020-05-31
申请号：MDE20190460
申请日：2017-06-09
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： KOTSCHY ANDRAS , WEBER CSABA , VASAS ATTILA , MOLNAR BALAZS , KISS ARPAD , MACIAS ALBA , MURRAY JAMES BROOKE , LEWKOWICZ ELODIE , GENESTE OLIVIER , CHANRION MAIA , DEMARLES DIDIER
IPC: C07D487/04 , A61K31/519 , A61P35/00 , C07D495/04
Abstract: Compuşi cu formula (I) în care R1, R2, R3, n şi W sunt definiţi în descriere. Medicamente.
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公开(公告)号：CA3083320A1
公开(公告)日：2019-06-06
申请号：CA3083320
申请日：2018-11-28
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： KOTSCHY ANDRAS , WEBER CSABA , VASAS ATTILA , KISS ARPAD , MOLNAR BALAZS , STROFEK AGNES , KUN VILIBALD , MURRAY JAMES BROOKE , MACIAS ALBA , LEWKOWICZ ELODIE , CHANRION MAIA , IVANSCHITZ LISA , GENESTE OLIVIER
IPC: C07D471/04 , A61K31/519 , A61K31/52 , A61P35/00 , A61P37/00 , C07D473/30 , C07D495/04
Abstract: Compounds of formula (I): wherein R1, R2, R3, B, W, Z, m and n are as defined in the description The compounds of the present invention have pro-apoptotic and/ or anti-proliferative properties making it possible to use them in pathologies involving a defect in apoptosis, such as, for example, in the treatment of cancer and of immune and auto-immune diseases.
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公开(公告)号：ECSP18090144A
公开(公告)日：2019-01-31
申请号：ECDI201890144
申请日：2018-12-04
Applicant: SERVIER LAB , VERNALIS R D LTD
Inventor： DEMARLES DIDIER , MURRAY JAMES BROOKE , GENESTE OLIVIER , KISS ARPAD , WEBER CSABA , KOTSCHY ANDRAS , MOLNAR BALAZS , MACIAS ALBA , CHANRION MAIA , VASAS ATTILA , LEWKOWICZ ELODIE
IPC: A61K31/519 , A61P35/00 , C07D487/04
Abstract: Compuestos de fórmula (I): (VER LA FORMULA EN LA MEMORIA TECNICA) en la que R1, R2, R3, n y W son como se han definido en la descripción. Medicamentos.
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公开(公告)号：ECSP18090046A
公开(公告)日：2019-01-31
申请号：ECDI201890046
申请日：2018-12-04
Applicant: VERNALIS R D LTD , SERVIER LAB
Inventor： LEWKOWICZ ELODIE , MOLNAR BALAZS , DEMARLES DIDIER , KISS ARPAD , IVANSCHITZ LISA , GENESTE OLIVIER , MACIAS ALBA , KOTSCHY ANDRAS , MURRAY JAMES BROOKE , VASAS ATTILA , CHANRION MAIA , WEBER CSABA
IPC: A61K31/519 , C07D471/04
Abstract: Compuestos de fórmula (I): (FORMULA VER EN LA MEMORIA TECNICA) en la que R1, R2, J, K, L, n y W son como se han definido en la descripción. Medicamentos.
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