公开(公告)号：AT424198T

公开(公告)日：2009-03-15

申请号：AT03796628

申请日：2003-12-04

Applicant: VERTEX PHARMA

Inventor： JAIN-PANDEY JUGNU ,  FRAM ROBERT

IPC: A61K31/341 ,  A61K31/17 ,  A61K31/277 ,  A61K31/421 ,  A61K31/519 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K45/06 ,  A61P35/00 ,  A61P35/02 ,  A61P35/04

Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.