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1.发明申请COMPOSITIONS COMPRISING A COMBINATION OF DIPHENYL URA IMPDH INHIBITORS AND APOPTOSIS-INDUCING ANTI-CANCER AGENTS 审中-公开组合物包含二苯胺类URA IMPDH抑制剂和抗病毒诱导抗癌剂的组合
公开(公告)号：WO2004052349A3
公开(公告)日：2004-07-29
申请号：PCT/US0338523
申请日：2003-12-04
Applicant: VERTEX PHARMA , JAIN-PANDEY JUGNU , FRAM ROBERT J
Inventor： JAIN-PANDEY JUGNU , FRAM ROBERT J
IPC: A61K31/17 , A61K31/277 , A61K31/341 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04
CPC classification number: A61K31/7068 , A61K31/17 , A61K31/277 , A61K31/341 , A61K31/421 , A61K31/519 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61K2300/00
Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.
Abstract translation: 本发明涉及包含凋亡诱导抗癌剂和IMPDH抑制剂的组合物。 本发明还涉及用于诱导哺乳动物细胞凋亡和治疗肿瘤和癌症的方法。
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公开(公告)号：EP1766091A4
公开(公告)日：2009-03-18
申请号：EP05804844
申请日：2005-05-27
Applicant: VERTEX PHARMA
Inventor： JAIN-PANDEY JUGNU , HARDING MATTHEW W , RAMACHANDRAN RAVI , BOTFIELD MARTYN
CPC classification number: C12Q1/6883 , C12Q1/6837 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158
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公开(公告)号：CA2568405A1
公开(公告)日：2005-12-15
申请号：CA2568405
申请日：2005-05-27
Applicant: VERTEX PHARMA
Inventor： BOTFIELD MARTYN , RAMACHANDRAN RAVI , JAIN-PANDEY JUGNU , HARDING MATTHEW W
Abstract: The present invention is directed to methods for ameliorating reproductive disorders. More specifically, the present invention describes methods and compositions for using IL-17 in the treatment of various infertility-related defects.
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公开(公告)号：AU2003298868A1
公开(公告)日：2004-06-30
申请号：AU2003298868
申请日：2003-12-04
Applicant: VERTEX PHARMA
Inventor： JAIN-PANDEY JUGNU , FRAM ROBERT J
IPC: A61K31/17 , A61K31/277 , A61K31/341 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04 , A61K31/00
Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.
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公开(公告)号：CA2510006A1
公开(公告)日：2004-06-24
申请号：CA2510006
申请日：2003-12-04
Applicant: VERTEX PHARMA
Inventor： JAIN-PANDEY JUGNU , FRAM ROBERT J
IPC: A61K31/17 , A61K31/277 , A61K31/341 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04
Abstract: The present invention relates to compositions comprising an apoptosis induci ng anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammal s.
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Patent Agency Ranking
公开(公告)号：AU2003298868B2
公开(公告)日：2009-09-17
申请号：AU2003298868
申请日：2003-12-04
Applicant: VERTEX PHARMA
Inventor： FRAM ROBERT J , JAIN-PANDEY JUGNU
IPC: A61K31/17 , A61K31/277 , A61K31/341 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04
Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.
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公开(公告)号：AT424198T
公开(公告)日：2009-03-15
申请号：AT03796628
申请日：2003-12-04
Applicant: VERTEX PHARMA
Inventor： JAIN-PANDEY JUGNU , FRAM ROBERT
IPC: A61K31/341 , A61K31/17 , A61K31/277 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04
Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.
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公开(公告)号：CA2510006C
公开(公告)日：2012-02-07
申请号：CA2510006
申请日：2003-12-04
Applicant: VERTEX PHARMA
Inventor： JAIN-PANDEY JUGNU , FRAM ROBERT J
IPC: A61K31/7076 , A61K31/17 , A61K31/175 , A61K31/277 , A61K31/341 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04
Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.
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公开(公告)号：AU2005249446A8
公开(公告)日：2010-03-04
申请号：AU2005249446
申请日：2005-05-27
Applicant: VERTEX PHARMA
Inventor： RAMACHANDRAN RAVI , BOTFIELD MARTYN , HARDING MATTHEW W , JAIN-PANDEY JUGNU
Abstract: The present invention is directed to methods for ameliorating reproductive disorders. More specifically, the present invention describes methods and compositions for using IL-17 in the treatment of various infertility-related defects.
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公开(公告)号：DE60326488D1
公开(公告)日：2009-04-16
申请号：DE60326488
申请日：2003-12-04
Applicant: VERTEX PHARMA
Inventor： JAIN-PANDEY JUGNU , FRAM ROBERT J
IPC: A61K31/341 , A61K31/17 , A61K31/277 , A61K31/421 , A61K31/519 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , A61P35/00 , A61P35/02 , A61P35/04
Abstract: The present invention relates to compositions comprising an apoptosis inducing anti-cancer agent and an IMPDH inhibitor. This invention also relates to methods for inducing apoptosis and for treating tumors and cancers in mammals.
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