Patent search ap:("VERTEX PHARMA") AND inv:"KRAWIEC MARIUSZ M" Page 1

1.

发明专利
-氮雜雙環庚- -基三氟甲基苯基 -氧代- 三氟甲基 -二氫喹啉- -甲酰胺的固體形式未知

公开(公告)号：HK1173151A1

公开(公告)日：2013-07-05

申请号：HK13100461

申请日：2013-01-11

Applicant: VERTEX PHARMA

Inventor： ZHANG BEILI , KRAWIEC MARIUSZ M , LUISI BRIAN B , MEDEK ALES A

IPC: C07D20060101 , A61K20060101 , A61P20060101

2.

发明专利
SOLID FORMS OF N-(4-(7-AZABICYCLO[2.2.1]HEPTAN-7-YL)-2- (TRIFLUOROMETHYL)PHENYL)-4-OXO-5-(TRIFLUOROMETHYL)-1,4-DIHYDROQUINOLINE-3- CARBOXAMIDE N-(4-(7-[221]-7-)-2-())-4--5-()-1 4--3- 未知

公开(公告)号：HK1158650A1

公开(公告)日：2012-09-07

申请号：HK11113172

申请日：2011-12-06

Applicant: VERTEX PHARMA

Inventor： ZHANG BEILI B , KRAWIEC MARIUSZ M , BOTFIELD MARTYN M , GROOTENHUIS PETER D J PDJ , GOOR FREDRICK F VAN

IPC: C07D20060101 , A61K20060101 , A61P20060101

3.

发明专利
SOLID FORMS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3] DIOXOL-5-YL) CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL) BENZOIC ACID 3-(6-(1-(22-[D][13]-5-))-3- -2-) 未知

公开(公告)号：HK1146819A1

公开(公告)日：2011-07-15

申请号：HK11100358

申请日：2011-01-14

Applicant: VERTEX PHARMA

Inventor： KESHAVARZSHOKRI ALI A , ZHANG BEILI B , KRAWIEC MARIUSZ M

IPC: C07D20060101 , A61K20060101 , A61P20060101

Abstract: The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith.

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