公开(公告)号：AU2023215372A1

公开(公告)日：2024-08-22

申请号：AU2023215372

申请日：2023-02-02

Applicant: VERTEX PHARMA

Inventor： ANGELL PAUL TIMOTHY ,  BAEK MINSON ,  GAGNON KEVIN ,  MACK DANIEL JAMES ,  MEDEK ALES ,  PERESYPKIN ANDREY ,  ROEPER STEFANIE ,  SHRESTHA MUNA ,  SIESEL DAVID A ,  ZHOU JINGLAN ,  SHI YI

IPC: C07D498/14 ,  A61K31/437 ,  A61P11/00 ,  C07D213/81 ,  C07D413/04

Abstract: Processes and methods of preparing Compound (I) are disclosed. Crystalline forms of Compound (I), pharmaceutically acceptable salts, solvates, hydrates, and cocrystals thereof, pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.