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    TEMPERATURE-REGULATED CULTURE PLATES
    1.
    发明专利
    TEMPERATURE-REGULATED CULTURE PLATES 未知

    公开(公告)号：CA2641550A1

    公开(公告)日：2007-08-16

    申请号：CA2641550

    申请日：2007-02-07

    Applicant: WAFERGEN INC

    Inventor： HUDA AMJAD ,  JOSEPH VICTOR ,  ROGERS JOSEPH F

    IPC: C12Q1/68 ,  C12N5/00

    Abstract: Described herein are environmentally isolated tissue culture devices that may be used for cell culture, as well as systems including these devices and methods for using them. These devices may include control features for regulating the micro-environment within a well or wells of the device. For example, on-board features may regulate the temperature, humidity, pH, media level, media composition, CO2/O2/N2 levels, drug concentration, cell density, byproduct (or product) production, and mixing of materials within the chamber. Material may be added to or withdrawn from the wells of the device without opening the device. Also described herein are controllers for analyzing and controlling the micro- environment within the well. Thus, the plates described herein may be used without requiring a separate incubator, allowing cells to be analyzed (e.g., imaged) continuously, allowing real-time reactions while monitoring under a microscope for hours, days or even weeks.

    APPARATUS FOR HIGH THROUGHPUT CHEMICAL REACTIONS
    2.
    发明专利
    APPARATUS FOR HIGH THROUGHPUT CHEMICAL REACTIONS 未知

    公开(公告)号：CA2677833C

    公开(公告)日：2016-05-03

    申请号：CA2677833

    申请日：2008-01-22

    Applicant: WAFERGEN INC

    Inventor： JOSEPH VICTOR ,  HUDA AMJAD ,  SHIVJI ALNOOR

    IPC: B01J19/24 ,  C12M1/38 ,  C12P19/34

    Abstract: Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genome of an organism of interest.

    APPARATUS FOR HIGH THROUGHPUT CHEMICAL REACTIONS
    3.
    发明专利
    APPARATUS FOR HIGH THROUGHPUT CHEMICAL REACTIONS 未知

    公开(公告)号：CA2677833A1

    公开(公告)日：2008-07-31

    申请号：CA2677833

    申请日：2008-01-22

    Applicant: WAFERGEN INC

    Inventor： JOSEPH VICTOR ,  HUDA AMJAD ,  SHIVJI ALNOOR

    IPC: C08F2/01 ,  B01J19/08

    Abstract: Apparatus, systems, chips, and methods of performing a large number of si multaneous chemical reactions are provided herein. The chips of the inventio n comprise addressable units that can be addressed according to the temperat ure of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genome of an organism of interest.

    Temperature-regulated culture plates
    4.
    发明专利
    Temperature-regulated culture plates 未知

    公开(公告)号：AU2007212306A1

    公开(公告)日：2007-08-16

    申请号：AU2007212306

    申请日：2007-02-07

    Applicant: WAFERGEN INC

    Inventor： ROGERS JOSEPH F ,  HUDA AMJAD ,  JOSEPH VICTOR

    IPC: C12Q1/68 ,  C12N5/00

    Abstract: Described herein are environmentally isolated tissue culture devices that may be used for cell culture, as well as systems including these devices and methods for using them. These devices may include control features for regulating the micro-environment within a well or wells of the device. For example, on-board features may regulate the temperature, humidity, pH, media level, media composition, CO2/O2/N2 levels, drug concentration, cell density, byproduct (or product) production, and mixing of materials within the chamber. Material may be added to or withdrawn from the wells of the device without opening the device. Also described herein are controllers for analyzing and controlling the micro- environment within the well. Thus, the plates described herein may be used without requiring a separate incubator, allowing cells to be analyzed (e.g., imaged) continuously, allowing real-time reactions while monitoring under a microscope for hours, days or even weeks.

    TEMPERATURE-REGULATED CULTURE PLATES
    6.
    发明申请
    TEMPERATURE-REGULATED CULTURE PLATES 审中-公开
    温度调节培养板

    公开(公告)号：WO2007092571A3

    公开(公告)日：2007-12-27

    申请号：PCT/US2007003401

    申请日：2007-02-07

    Applicant: WAFERGEN INC ,  JOSEPH VICTOR ,  HUDA AMJAD ,  ROGERS JOSEPH F

    Inventor： JOSEPH VICTOR ,  HUDA AMJAD ,  ROGERS JOSEPH F

    IPC: C12Q1/68 ,  C12N5/00

    CPC classification number: C12M23/48 ,  C12M23/12 ,  C12M23/22 ,  C12M41/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/44

    Abstract: Described herein are environmentally isolated tissue culture devices that may be used for cell culture, as well as systems including these devices and methods for using them. These devices may include control features for regulating the micro-environment within a well or wells of the device. For example, on-board features may regulate the temperature, humidity, pH, media level, media composition, CO 2 /O 2 /N 2 levels, drug concentration, cell density, byproduct (or product) production, and mixing of materials within the chamber. Material may be added to or withdrawn from the wells of the device without opening the device. Also described herein are controllers for analyzing and controlling the micro- environment within the well. Thus, the plates described herein may be used without requiring a separate incubator, allowing cells to be analyzed (e.g., imaged) continuously, allowing real-time reactions while monitoring under a microscope for hours, days or even weeks.

    Abstract translation: 本文描述的是可用于细胞培养的环境分离的组织培养装置，以及包括这些装置的系统以及使用它们的方法。 这些设备可以包括用于调节设备的一个或多个井内的微环境的控制特征。 例如，板载功能可以调节温度，湿度，pH值，介质水平，介质组成，CO 2 / SUB <2> / N 2 水平，药物浓度，细胞密度，副产物（或产物）生产以及室内物质的混合。 可以在不打开设备的情况下将材料添加到设备的孔中或从设备的孔中取出材料。 本文还描述了用于分析和控制井内的微环境的控制器。 因此，本文所述的平板可以在不需要单独的培养箱的情况下使用，从而允许细胞连续分析（例如成像），允许实时反应，同时在显微镜下监测几小时，几天甚至几周。

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