-
公开(公告)号：WO2009099941A3
公开(公告)日：2009-08-13
申请号：PCT/US2009/032627
申请日：2009-01-30
Applicant: WASHINGTON UNIVERSITY IN ST. LOUIS , CAIRNS, Niegel, J. , BALOH, Robert, H. , PESTRONK, Alan , GITCHO, Michael A. , GOATE, Alison, M.
Inventor： CAIRNS, Niegel, J. , BALOH, Robert, H. , PESTRONK, Alan , GITCHO, Michael A. , GOATE, Alison, M.
Abstract: Nucleic acids and peptides and methods of using thereof to identify subjects at risk for a TDP-43 proteinopathy are disclosed An array is also disclosed which contains the nucleic acids and peptides
-
2.发明申请AUTOANTIBODIES AND THEIR TARGETS IN THE DIAGNOSIS OF PERIPHERAL NEUROPATHIES 审中-公开外周神经病变诊断中的自动诊断及其目标
公开(公告)号：WO1993003375A1
公开(公告)日：1993-02-18
申请号：PCT/US1992006545
申请日：1992-08-07
Applicant: WASHINGTON UNIVERSITY
Inventor： WASHINGTON UNIVERSITY , PESTRONK, Alan
IPC: G01N33/564
CPC classification number: G01N33/564 , A01K67/027 , C07K14/47 , C07K16/18 , G01N33/6854 , G01N33/6875 , G01N33/6893 , G01N33/6896 , G01N2800/28 , G01N2800/285 , Y10S436/811
Abstract: The present invention relates to methods of diagnosing peripheral neuropathies which comprises the steps of determining the titer of autoantibodies directed toward particular nervous system antigens. It also provides for substantially purified preparations of specific antigens, namely neuroprotein-1, neuroprotein-2, neuroprotein-3, neuroprotein-4, neuroprotein-5, neuroprotein-9 and histone H3 which may be used in such diagnostic methods.
Abstract translation: 本发明涉及诊断周围神经病变的方法，其包括确定针对特定神经系统抗原的自身抗体滴度的步骤。 它还提供可用于这种诊断方法的特异抗原的基本上纯化的制剂，即神经蛋白-1，神经蛋白-2，神经蛋白-3，神经蛋白-4，神经蛋白-5，神经蛋白-9和组蛋白H3。
-
3.发明申请ANTIBODIES TO DISULFATED HEPARIN DISACCHARIDE IN THE DIAGNOSIS OF NEUROPATHY 审中-公开在神经病变诊断中解剖的尿蛋白异常的抗体
公开(公告)号：WO2011028921A1
公开(公告)日：2011-03-10
申请号：PCT/US2010/047706
申请日：2010-09-02
Applicant: THE WASHINGTON UNIVERSITY , PESTRONK, Alan
Inventor： PESTRONK, Alan
CPC classification number: G01N33/6896 , C07K16/42 , G01N33/6854 , G01N2400/40 , G01N2800/28 , G01N2800/2835
Abstract: Methods aiding in the diagnosis of certain neuropathies are disclosed, in which the titer of antibodies to a disulfated heparin disaccharide is assessed in a test sample from an subject. Also disclosed are apparatus and kits that can be used in the methods of the invention.
Abstract translation: 公开了帮助诊断某些神经病的方法，其中在来自受试者的测试样品中评估了对二硫酸化肝素二糖的抗体滴度。 还公开了可用于本发明方法的装置和试剂盒。
-
-
Search Results
3
records
(took 0.021 seconds)
