HYBRID GRADIENT DELIVERY SYSTEM AND OPERATION
    1.
    发明申请
    HYBRID GRADIENT DELIVERY SYSTEM AND OPERATION 审中-公开
    混合梯度交付系统和操作

    公开(公告)号:WO2013090147A3

    公开(公告)日:2016-02-04

    申请号:PCT/US2012068520

    申请日:2012-12-07

    Abstract: A liquid chromatography system includes a gradient proportioning valve in fluidic communication with sources of solvent. From the solvent sources, the gradient proportioning valve produces a low-pressure gradient stream. A first pump is in fluidic communication with the gradient proportioning valve to receive, pressurize, and move the pressurized low-pressure gradient stream to a flow-combining device. A second pump operates in parallel with the first pump and moves a pressurized solvent stream to the flow-combining device where the pressurized solvent stream combines with the low-pressure gradient stream to produce a high-pressure gradient stream. A second gradient proportioning valve can produce, from a second plurality of sources of solvent, a second low-pressure gradient stream, wherein the solvent stream moved by the second pump to the flow-combining device and combined with the other low-pressure gradient stream comprises the second low-pressure gradient stream.

    Abstract translation: 液相色谱系统包括与溶剂源流体连通的梯度比例阀。 从溶剂来源,梯度比例阀产生低压梯度流。 第一泵与梯度比例阀流体连通,以将加压的低压梯度流接收,加压并移动到流动组合装置。 第二泵与第一泵平行操作并将加压溶剂流移动到流动组合装置,其中加压溶剂流与低压梯度流结合以产生高压梯度流。 第二梯度比例阀可以从第二多个溶剂源产生第二低压梯度流,其中溶剂流由第二泵移动到流动组合装置并与其它低压梯度流 包括第二低压梯度流。

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