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    SAMPLE METERING AND INJECTION FOR LIQUID CHROMATOGRAPHY
    1.
    发明申请
    SAMPLE METERING AND INJECTION FOR LIQUID CHROMATOGRAPHY 审中-公开

    公开(公告)号：WO2021133646A1

    公开(公告)日：2021-07-01

    申请号：PCT/US2020/065802

    申请日：2020-12-18

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： BURNETT, Joshua, A. ,  SOLOW, Rose ,  SIMPSON, David, A.

    IPC: G01N30/20 ,  G01N2030/027 ,  G01N2030/201 ,  G01N2030/202 ,  G01N30/24 ,  G01N30/36

    Abstract: Described are a method and a fluidic network for acquiring and injecting a chromatographic sample into a chromatography system flow. The fluidic network includes a metering pump module 60, a sample needle 50, a needle seal 52 and an injection valve48. The metering pump module includes a metering pump and a pressure transducer in serial fluidic communication. When the injection valve 48 is in a first valve state, the injection valve is configured to fluidically terminate ports of the metering pump module 60. When the injection valve 48 is in a second valve state, the injection valve is configured to fluidically couple a fluidic path that includes the metering pump module 60 and sample needle 50 into the system flow of a chromatography system without resulting in a substantial change in the pressure of the system flow.

    NEEDLE DRIVE, SYSTEM AND METHOD
    2.
    发明申请
    NEEDLE DRIVE, SYSTEM AND METHOD 审中-公开

    公开(公告)号：WO2021188530A1

    公开(公告)日：2021-09-23

    申请号：PCT/US2021/022552

    申请日：2021-03-16

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： BURNETT, Joshua, A. ,  SOLOW, Rose ,  SIMPSON, David, A. ,  LEMELIN, Marc, E.

    IPC: G01N30/24

    Abstract: A liquid chromatography sample manager includes a thermal chamber, a sample platter 110 mounted in the thermal chamber, and a needle drive including a base 230 having a shaft configured to rotate about a vertical axis, the base attachable to an interior of a sample manager of a liquid chromatography system. The needle drive further includes a needle assembly attached to the base, the needle assembly including a sample needle 122, and a drive system 112 attached to the base, the drive system including a sample needle motor configured to impart vertical movement of the sample needle.

    SAMPLE ORGANIZER, TRAY, SYSTEM AND METHOD
    4.
    发明申请
    SAMPLE ORGANIZER, TRAY, SYSTEM AND METHOD 审中-公开

    公开(公告)号：WO2019241337A1

    公开(公告)日：2019-12-19

    申请号：PCT/US2019/036698

    申请日：2019-06-12

    Applicant: WATERS TECHNOLOGIES CORPORATION

    Inventor： SIMPSON, David, A. ,  BURNETT, Joshua, A. ,  LEMELIN, Marc, E.

    IPC: G01N30/24 ,  G01N35/00 ,  G01N35/04

    Abstract: A liquid chromatography sample organizer includes a first chamber, a plurality of stacked sample organizer shelves mounted within the first chamber each individually configured to store a sample-vial carrier including a sample, and a shelf magnet affixed to a surface of each of the plurality of stacked sample organizer shelves. A portion of the first chamber is configured to be located adjacent to, and open to, a sample manager configured to inject liquid chromatography samples into a chromatographic flow stream. Disclosed further is a liquid chromatography system having the sample organizer, a sample drawer, and a method of transferring samples between a sample manager and the sample organizer.

    SAMPLE METERING AND INJECTION FOR LIQUID CHROMATOGRAPHY
    5.
    发明公开
    SAMPLE METERING AND INJECTION FOR LIQUID CHROMATOGRAPHY 审中-公开

    公开(公告)号：EP4549929A2

    公开(公告)日：2025-05-07

    申请号：EP25157069.3

    申请日：2020-12-18

    Applicant: Waters Technologies Corporation

    Inventor： BURNETT, Joshua, A. ,  SOLOW, Rose ,  SIMPSON, David, A.

    IPC: G01N30/20

    Abstract: Described are a method and a fluidic network for acquiring and injecting a chromatographic sample into a chromatography system flow. The fluidic network includes a metering pump module having a metering pump and a pressure transducer in serial fluidic communication with each other. The metering pump module has a first pump port and a second pump port. The fluidic networking also includes a sample needle having a needle tip; a needle seal configured to receive the needle tip of the sample needle; and a valve operable in at least a first valve state and a second valve state, and being in fluidic communication with the metering pump module and the needle seal. When the valve is in the first valve state, the metering pump is operable to acquire a sample through the sample needle. When the valve is in the first valve state and the needle tip is in the needle seal, the metering pump is operable to pressurize the fluidic network to a system pressure. When the valve is in the second valve state and the needle tip is in the needle seal, a system flow passes through the fluidic network such that the sample acquired through the sample needle is merged into the system flow.

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