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公开(公告)号：EP0641224B1
公开(公告)日：1998-08-19
申请号：EP93909715.0
申请日：1993-05-19
Applicant: WESTAIM TECHNOLOGIES INC.
Inventor： BURRELL, Robert, Edward , MORRIS, Larry, R.
CPC classification number: C23C14/225 , A01N59/16 , A61B2018/00119 , A61L17/145 , A61L27/306 , A61L27/54 , A61L29/106 , A61L29/16 , A61L31/16 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , C23C14/0036 , C23C14/025 , C23C14/06 , C23C14/0688 , C23C14/086 , C23C14/14 , C23C14/16 , C23C14/205 , C23C14/35 , C23C14/588 , H01H2300/014 , Y10S977/781 , Y10S977/89 , Y10S977/891 , Y10S977/904 , Y10S977/931
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公开(公告)号：EP0641224A1
公开(公告)日：1995-03-08
申请号：EP93909715.0
申请日：1993-05-19
Applicant: WESTAIM TECHNOLOGIES INC.
Inventor： BURRELL, Robert, Edward , MORRIS, Larry, R.
CPC classification number: C23C14/225 , A01N59/16 , A61B2018/00119 , A61L17/145 , A61L27/306 , A61L27/54 , A61L29/106 , A61L29/16 , A61L31/16 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/602 , A61L2300/606 , C23C14/0036 , C23C14/025 , C23C14/06 , C23C14/0688 , C23C14/086 , C23C14/14 , C23C14/16 , C23C14/205 , C23C14/35 , C23C14/588 , H01H2300/014 , Y10S977/781 , Y10S977/89 , Y10S977/891 , Y10S977/904 , Y10S977/931
Abstract: Anti-microbial coatings and method of forming same on medical devices are provided. The coatings are formed by depositing a biocompatible metal by vapour deposition techniques to produce atomic disorder in the coating such that a sustained release of metal ions sufficient to produce an anti-microbial effect is achieved. Preferred deposition conditions to achieve atomic disorder include a lower than normal substrate temperature, and one or more of a higher than normal working gas pressure and a lower than normal angle of incidence of coating flux. Anti-microbial powders formed by mechanical working to produce atomic disorder are also provided. The invention extends to other metal coatings and powders similarly formed so as to provide enhanced solubility.
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