公开(公告)号：WO2022232389A1

公开(公告)日：2022-11-03

申请号：PCT/US2022/026727

申请日：2022-04-28

Applicant: WORCESTER POLYTECHNIC INSTITUTE

Inventor： HEIGHTON, Carolyn ,  GAUDETTE, Logan ,  KALESHIAN, Gregory ,  HOLM, Camden ,  BONARRIGO, Paul ,  PINS, George ,  MAGIT, David ,  PHANEUF, Matthew ,  LONG, Nathaniel ,  KASSAB, Rayan

IPC: A61F2/08 ,  A61L27/56 ,  A61L27/54 ,  A61L27/24 ,  A61L27/36

Abstract: A ligament repair device and method is particularly suited to the demands of UCL repair using a scaffold device for surgical implantation across a torn ligament section. The implantable device includes an encapsulation of a therapeutic element for increasing cell proliferation and growth eluted through a controlled release storage element adapted to release the therapeutic agent over time as the cell growth progresses and the scaffold structure degrades or is absorbed in favor of the new cell growth for ligament repair. Reduced recovery time is afforded by the need for only an relatively small incision for implantation. The introduction of a physiologically relevant drug delivery scaffold encourages more rapid cell growth over passive, physical repairs to the connective tissue.