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公开(公告)号:WO2023003934A1
公开(公告)日:2023-01-26
申请号:PCT/US2022/037680
申请日:2022-07-20
Applicant: WORCESTER POLYTECHNIC INSTITUTE
Inventor: ZHANG, Haichong , GAO, Shang
Abstract: A photoacoustic imaging approach identifies, concurrently with ablation therapy, an extent of the ablation by measuring and rendering a necrotic extent of treated tissue in a treatment region. Laser pulsed light directed at the treatment region induces an acoustic (ultrasound) signal for differentiating ablated tissue from its non-ablative counterpart based on a photoacoustic spectrum variation. The acoustic signal indicates a range of necrotic extent based on a quantified ablated tissue contrast and a total contrast of both necrotic and non-necrotic tissue, defined as a fraction for computing a degree of necrosis. Generation of an image indicating the degree of necrosis allows continuous or near continuous feedback for ablation therapy guidance to ensure complete and effective ablation of the proper tissue in the treatment region.
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公开(公告)号:WO2021087068A1
公开(公告)日:2021-05-06
申请号:PCT/US2020/057892
申请日:2020-10-29
Applicant: WORCESTER POLYTECHNIC INSTITUTE
Inventor: ZHANG, Haichong , TSUMURA, Ryosuke , TANG, Yichuan
IPC: A61B8/00
Abstract: A Ring-Arrayed Forward-viewing (RAF) ultrasound imaging and administration device combines an ultrasonic (US) US imager including a plurality of single element transducers arranged in a circular frame to define a ring array, and an instrument posture tracking circuit coupled to the ring array for performing RF (radio frequency) data acquisition with the plurality of ring-arrayed transducers. A needle holster is concentrically disposed in the ring array and is adapted to receive and direct an insertion instrument such as a needle, probe or extraction tool along an axis defined by a center of the ring array directed by the concentric needle holster. The tracking circuit includes a processor having instructions for instrument posture tracking and US imaging.
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公开(公告)号:EP4051120A1
公开(公告)日:2022-09-07
申请号:EP20883393.9
申请日:2020-10-29
Applicant: Worcester Polytechnic Institute
Inventor: ZHANG, Haichong , TSUMURA, Ryosuke , TANG, Yichuan
IPC: A61B8/00
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