公开(公告)号：EP0595506A3

公开(公告)日：1994-12-07

申请号：EP93308210.9

申请日：1993-10-14

Applicant: XILLIX TECHNOLOGIES CORPORATION

Inventor： MacAulay, Calum ,  Palcic, Branko ,  Garner, David ,  Harrison, Alan ,  Jaggi, Bruno

IPC: G01N33/483 ,  G01N15/10 ,  G01N21/00

CPC classification number: G01N33/5091 ,  G01N15/1475 ,  G01N33/5017 ,  G06K9/00127

Abstract: An appatatus and a method for detecting malignancy associated changes relies on use of the microscope having a high sampling density light transducer. Images of the cell nuclei are obtained in precise focus. The images are segmented using a relocation algorithm for precisely locating the edge of the nucleus. The features of the images including DNA distribution are analyzed using multivariate analysis to detect malignance associated changes.

公开(公告)号：EP0595506A2

公开(公告)日：1994-05-04

申请号：EP93308210.9

申请日：1993-10-14

Applicant: XILLIX TECHNOLOGIES CORPORATION

Inventor： MacAulay, Calum ,  Palcic, Branko ,  Garner, David ,  Harrison, Alan ,  Jaggi, Bruno

IPC: G01N33/483 ,  G01N15/10 ,  G01N21/00

CPC classification number: G01N33/5091 ,  G01N15/1475 ,  G01N33/5017 ,  G06K9/00127

Abstract: An appatatus and a method for detecting malignancy associated changes relies on use of the microscope having a high sampling density light transducer. Images of the cell nuclei are obtained in precise focus. The images are segmented using a relocation algorithm for precisely locating the edge of the nucleus. The features of the images including DNA distribution are analyzed using multivariate analysis to detect malignance associated changes.

Abstract translation: 在appatatus和用于检测恶性肿瘤相关的变化的方法依赖于使用具有高采样密度的光传感器的显微镜。 细胞核的图像被获得的聚焦准确度。 该图像是使用重定位算法精确定位核的边缘分段。 包括DNA分布的图像的特征被使用多变量分析，以检测恶性相关的变化进行分析。