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公开(公告)号：EP0244802A2
公开(公告)日：1987-11-11
申请号：EP87106438.2
申请日：1987-05-04
Inventor： Wilchek, Meir , Cabrera, Karin
IPC: B01J20/32
CPC classification number: B01J20/289 , B01J20/103 , B01J20/28004 , B01J20/28019 , B01J20/28078 , B01J20/3092 , B01J20/3204 , B01J20/3219 , B01J20/3257 , B01J20/3259 , B01J20/3261 , B01J20/3263 , B01J20/3274 , B01J2220/54 , B01J2220/58
Abstract: The invention relates to modified silica, substituted with a variety of substituents. There is provided a product termed primary hydroxyl silica where there are attached to the silica substituents bearing a single hydroxyl group. Furthermore there are provided a wide variety of derivatives of such hydroxy-silica, which are of value in affinity chromatography and for various other uses. The products combine the thermal and mechanical stability of the silica used as carrier with the useful properties of the substituents.
Abstract translation: 本发明涉及被各种取代基取代的改性二氧化硅。 提供了称为伯羟基二氧化硅的产物，其中连接到具有单个羟基的二氧化硅取代基。 此外，提供了这种羟基二氧化硅的各种衍生物，其在亲和层析中和各种其它用途中是有价值的。 该产品将用作载体的二氧化硅的热和机械稳定性与取代基的有用性质相结合。
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Patent Agency Ranking
公开(公告)号：EP0305968A2
公开(公告)日：1989-03-08
申请号：EP88114131.1
申请日：1988-08-30
Inventor： Mirelman, David , Wilchek, Meir
IPC: A61K9/18 , A61K9/14 , A61K47/00 , A61K31/415 , A61K31/285 , A61K31/47 , A61K31/435 , A61K31/165 , A61K31/42 , A61K31/255 , A61K31/54
CPC classification number: A61K9/1676 , A61K9/167 , A61K47/52 , Y02A50/486
Abstract: The invention relates to pharmaceutical compositions for use against protozoa. The compositions comprise particles in the micron-size range which are physiologically acceptable to humans and which can be ingested by protozoa. The particles, which can be of natural materials such as silica or the like, serve as carrirs of an effective anti-protozoal drug. A variety of anti-amebic drugs can be bound to such particles.
Abstract translation: 本发明涉及用于抗原生动物的药物组合物。 组合物包含微生物范围的颗粒，它们是生理上可接受的并且可被原生动物吸收。 可以是天然材料如二氧化硅等的颗粒用作有效的抗原虫药物的卡里尔。 各种抗阿米巴药物可以与这种颗粒结合。
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公开(公告)号：EP0305968A3
公开(公告)日：1989-04-05
申请号：EP88114131.1
申请日：1988-08-30
Inventor： Mirelman, David , Wilchek, Meir
IPC: A61K9/18 , A61K9/14 , A61K47/00 , A61K31/415 , A61K31/285 , A61K31/47 , A61K31/435 , A61K31/165 , A61K31/42 , A61K31/255 , A61K31/54
CPC classification number: A61K9/1676 , A61K9/167 , A61K47/52 , Y02A50/486
Abstract: The invention relates to pharmaceutical compositions for use against protozoa. The compositions comprise particles in the micron-size range which are physiologically acceptable to humans and which can be ingested by protozoa. The particles, which can be of natural materials such as silica or the like, serve as carrirs of an effective anti-protozoal drug. A variety of anti-amebic drugs can be bound to such particles.
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公开(公告)号：EP0190464A2
公开(公告)日：1986-08-13
申请号：EP85116663.7
申请日：1985-12-31
Inventor： Arnon, Ruth , Wilchek, Meir , Schechter, Bilha
CPC classification number: A61K33/24 , A61K47/61 , A61K47/645
Abstract: Described are complexes between a physiologically acceptable macromolecular carrier and an anti-tumor active platinum compound useful as anti-cancer drugs.
Abstract translation: 描述了可用作抗癌药物的生理学上可接受的大分子载体和抗肿瘤活性铂化合物之间的复合物。
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公开(公告)号：EP0244802A3
公开(公告)日：1988-07-20
申请号：EP87106438
申请日：1987-05-04
Inventor： Wilchek, Meir , Cabrera, Karin
IPC: B01J20/32
CPC classification number: B01J20/289 , B01J20/103 , B01J20/28004 , B01J20/28019 , B01J20/28078 , B01J20/3092 , B01J20/3204 , B01J20/3219 , B01J20/3257 , B01J20/3259 , B01J20/3261 , B01J20/3263 , B01J20/3274 , B01J2220/54 , B01J2220/58
Abstract: The invention relates to modified silica, substituted with a variety of substituents. There is provided a product termed primary hydroxyl silica where there are attached to the silica substituents bearing a single hydroxyl group. Furthermore there are provided a wide variety of derivatives of such hydroxy-silica, which are of value in affinity chromatography and for various other uses. The products combine the thermal and mechanical stability of the silica used as carrier with the useful properties of the substituents.
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公开(公告)号：EP0190464A3
公开(公告)日：1987-02-04
申请号：EP85116663
申请日：1985-12-31
Inventor： Arnon, Ruth , Wilchek, Meir , Schechter, Bilha
CPC classification number: A61K33/24 , A61K47/61 , A61K47/645
Abstract: Described are complexes between a physiologically acceptable macromolecular carrier and an anti-tumor active platinum compound useful as anti-cancer drugs.
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