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公开(公告)号：US20220136064A1
公开(公告)日：2022-05-05
申请号：US17429279
申请日：2020-02-10
Inventor： Ayman F. Abuelela , Alyaa M. Abdel-Haleem , Xin Gao , Jasmeen S. Merzaban
IPC: C12Q1/6886
Abstract: Compositions and method of cancer diagnosis and prognosis are disclosed. The methods rely on the expression profile of a 55 O-glycan forming GT (OGFGT) genes in multi-dimensional space was sufficient to classify cancer types from cancer patient samples in. These OGFGT genes ae used to distinguish between normal and cancer samples and cancer subtypes promoting the huge potential of utilizing this set of genes in diagnostic applications. The expression signature of OGFGT genes can also be used to determine survival profiles in samples from GBM patient samples.
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公开(公告)号：US11319490B2
公开(公告)日：2022-05-03
申请号：US17141963
申请日：2021-01-05
Inventor： Remi Mahfouz , Ola Ali , Isidoro Morales Osorio , Wei Xu , Xinglong Dong , Yu Han
Abstract: An integrated method for mesophase pitch and petrochemicals production. The method including supplying crude oil to a reactor vessel; heating the crude oil in the reactor vessel to a predetermined temperature for a predetermined amount of time; reducing asphaltene content in the crude oil by allowing polymerization reactions to occur in the reactor vessel at an elevated pressure in the absence of oxygen; producing a three-phase upgraded hydrocarbon product comprising gas, liquid, and solid hydrocarbon components, where the liquid hydrocarbon component comprises deasphalted oil and the solid hydrocarbon component comprises mesophase pitch; separating the gas, liquid, and solid hydrocarbon components; directly utilizing the liquid hydrocarbon component for petrochemicals production; and directly utilizing the solid hydrocarbon component for carbon artifact production.
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公开(公告)号：US20220094441A1
公开(公告)日：2022-03-24
申请号：US17422939
申请日：2020-02-19
Inventor： Boon Siew OOI , Chun Hong KANG , Tien Khee NG
IPC: H04B10/61 , G02B6/12 , G02B6/10 , H04B10/116 , F21V8/00
Abstract: A large-area, waveguide-based, high-speed ultraviolet and visible light photodetector system for optical wireless communication includes a substrate; plural, parallel, waveguides formed directly on the substrate and including a high quantum-yield wavelength-converting material of semiconductor nature; an optical coupling system optically connected to each one of the plural, parallel, waveguides; and a photodetector optically connected to the optical coupling system and configured to detect an outgoing light. The wavelength-converting material converts a first wavelength of an incoming light at high-speed, received by the plural, parallel, waveguides, into a second wavelength of the outgoing light. The first wavelength is different from the second wavelength, and the first and second wavelengths are between 200 and 800 nm.
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公开(公告)号：US20220081467A1
公开(公告)日：2022-03-17
申请号：US17415600
申请日：2019-12-20
Inventor： Vlad-Stefan Raducanu , Muhammad Tehseen , Fahad Rashid , Samir M. Hamdan
Abstract: Described are affinity purification system that includes a carrier/surface that is non-cellular, and sliding clamp (SC) protein, and methods for purifying proteins that bind to the SC. The SC is associated with the carrier/surface via covalent/non-covalent interactions. To attain control of coupling site, the SC can be mutated via site-directed mutagenesis to introduce an exogenous residue and, the exogenous internal residue is conjugated to the non-cellular surface through the linker. The SC can also be coupled to the carrier via non-covalent interactions such as the affinity interactions involved in ligand/binding partner complex formation.
The SC-based affinity purification system are used in a purification column as bait proteins, to isolate SC binding partners or non SC-binding proteins engineered to contain a SC binding site prior to its purification.-
公开(公告)号：US11274983B2
公开(公告)日：2022-03-15
申请号：US16625521
申请日：2018-06-15
Inventor： Amal Hajjaj , Md Abdullah Al Hafiz , Mohammad Ibrahim Younis
Abstract: An electromechanical pressure sensor includes an electromechanical resonator having a driving electrode, a sensing electrode, and a beam resonator arranged between the driving and sensing electrodes. The beam resonator includes a resonator beam coupled on a first end to a first fixed anchor and coupled on a second end to a fixed second fixed anchor. The electromechanical resonator also includes a first voltage source coupled to the driving electrode and configured to provide an alternating current to the driving electrode and a second voltage source coupled to the first fixed anchor. The second voltage source provides a DC bias to the resonator beam. The electromechanical resonator further includes a third voltage source coupled to the resonator beam via the first and second fixed anchors. The third voltage source is configured to supply a voltage to the resonator beam that results in a temperature differential between the resonator beam and the first and second fixed anchors. The electromechanical resonator also includes a processor coupled to the sensing electrode and configured to correlate a voltage on the sensing electrode with a pressure value.
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Patent Agency Ranking
公开(公告)号：US20220069824A1
公开(公告)日：2022-03-03
申请号：US17411698
申请日：2021-08-25
Inventor： Sherif Adekunle TELLA , Mohammad Ibrahim YOUNIS
Abstract: A cascadable resonator logic system includes a substrate; a first straight beam anchored with a first end to the substrate; a second straight beam anchored with a first end to the substrate; a first arch beam, which is curved, and is attached with a first end to a second end of the first straight beam, at a first joint, and with a second end to a second end of the second straight beam, at a second joint, so that both the first and second ends of the first arch beam are suspended above the substrate; and a second arch beam, which is also curved, and is attached with a first end to the second joint, and a second end is anchored to the substrate.
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公开(公告)号：US11264238B2
公开(公告)日：2022-03-01
申请号：US16764623
申请日：2018-12-04
Inventor： Xiaohang Li , Kaikai Liu
Abstract: A method for forming a semiconductor device involves selecting a substrate on which a wurtzite III-nitride alloy layer will be formed, and a piezoelectric polarization and an effective piezoelectric coefficient for the wurtzite III-nitride alloy layer. It is determined whether there is a wurtzite III-nitride alloy composition satisfying the selected effective piezoelectric coefficient. It is also determined whether there is a thickness for a layer formed from the wurtzite III-nitride alloy composition satisfying the selected piezoelectric polarization based on the selected substrate and the selected effective piezoelectric coefficient. Responsive to the determination that there is a wurtzite III-nitride alloy composition having a lattice constant satisfying the selected effective piezoelectric coefficient and a thickness for the layer formed from the wurtzite III-nitride alloy composition satisfying the selected piezoelectric polarization, the wurtzite III-nitride alloy layer is formed on the substrate having the wurtzite III-nitride alloy composition satisfying the selected effective piezoelectric coefficient and having the thickness satisfying the selected piezoelectric polarization.
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公开(公告)号：US20220033556A1
公开(公告)日：2022-02-03
申请号：US17277125
申请日：2019-09-17
Inventor： Xiaoshuang FENG , Jobi VARGHESE , Yves GNANOU , Nikos HADJICHRISTIDIS , Mingchen JIA , Dhanya AUGUSTINE
IPC: C08F293/00 , C08G65/12 , C08G65/26 , C08G63/664 , C08G64/34
Abstract: Embodiments include degradable polyethers comprising ester units from a cyclic ester or carbonate units from carbon dioxide incorporated into a poly(ethylene oxide) backbone or a multifunctional core of a degradable polyether star. Embodiments include methods of forming a degradable polyether comprising contacting an ethylene oxide monomer with a lactide monomer or carbon dioxide in the presence of an alkyl borane and an initiator. Embodiments include methods of forming degradable polyether stars comprising contacting a diepoxide monomer with carbon dioxide and/or a cyclic ester in the presence of an initiator and a first amount of an alkyl borane to form a multifunctional core comprising degradable carbonate linkages and/or degradable ester linkages, and contacting the multifunctional core with an ethylene oxide monomer in the presence of a second amount of an alkyl borane to form arms of a polyether attached to the degradable multifunctional core.
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公开(公告)号：US11240015B2
公开(公告)日：2022-02-01
申请号：US16132017
申请日：2018-09-14
Applicant: CUP Sciences, Inc. , The University Court of the University of St. Andrews , King Abdullah University of Science and Technology
Inventor： Aluizio M. Cruz , Andrea Fratalocchi , Valerio Mazzone , Andrea Di Falco
Abstract: In an aspect, the present invention provides an optical encryption terminal for generating and distributing a cryptographic key signal in a cryptography key distribution system having at least two optical encryption terminals. The optical encryption terminal comprises an electronic processing unit and the optical encryption terminal is configured to selectively receive optical input signals generated by a source of electromagnetic radiation and optical input signals generated by a further optical encryption terminal, and to selectively output first optical output signals to a detection element and second optical output signals to the further optical encryption terminal, wherein the first optical output signals are based on the optical input signals generated by the further optical encryption terminal and transformed in accordance with an optical encryption pattern provided at the optical encryption terminal. Furthermore, the optical encryption terminal is configured to determine, using the electronic processing unit, a cryptographic key signal on the basis of at least one radiometric and/or photometric quantity associated with the optical output signals detected by the detection element.
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公开(公告)号：US11235823B2
公开(公告)日：2022-02-01
申请号：US16696085
申请日：2019-11-26
Inventor： Mohamed Abdelkader , Fadl Abdellatif , Jeff S. Shamma
IPC: B62D57/024 , G06T7/50 , G01S17/86 , B64C39/02 , G05D1/00 , G06K9/00 , H04N5/222 , G01B17/02 , B60R11/00 , B60G3/01 , G01N29/265 , G08G5/00 , F17D5/00 , B60B19/00 , G01B7/28 , B60K1/02 , B62D21/09 , B60G11/00 , B62D61/12 , G01N29/04 , B62D9/00 , B64C25/24 , B64C25/36 , B64C25/40 , B64D1/02 , G05D1/10 , B64C25/32 , G01S17/89
Abstract: An unmanned aerial vehicle (UAV) autonomously perching on a curved surface from a starting position is provided. The UAV includes: a 3D depth camera configured to capture and output 3D point clouds of scenes from the UAV including the curved surface; a 2D LIDAR system configured to capture and output 2D slices of the scenes; and a control circuit. The control circuit is configured to: control the depth camera and the LIDAR system to capture the 3D point clouds and the 2D slices, respectively, of the scenes; input the captured 3D point clouds from the depth camera and the captured 2D slices from the LIDAR system; autonomously detect and localize the curved surface using the captured 3D point clouds and 2D slices; and autonomously direct the UAV from the starting position to a landing position on the curved surface based on the autonomous detection and localization of the curved surface.
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