Abstract:
The present invention provides compounds represented by the formula (Ie): and the formula (If): wherein each symbol is as defined in the specification.According to the present invention, these compounds have a DGAT inhibitory activity and are useful for the prophylaxis, treatment or improvement of diseases or pathologies caused by high expression or high activation of DGAT.
Abstract:
A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone.
Abstract:
The invention concerns a process for producing water-absorbing polymer, which comprises a base polymer A being mixed with a first aqueous solution B of at least one surface postcrosslinker and a second aqueous solution C of at least one polyvalent cation and thermally treated, wherein said base polymer A is based on at least 50% neutralized acid-functional monomer and said solutions B and C are metered wholly or partly concurrently through separate nozzles whereby a water-absorbing polymer having a high saline flow conductivity value is obtained.
Abstract:
The present invention relates to a process for producing water-absorbing polymeric particles by polymerizing a monomer solution, which comprises removing the polymer gel from the reactor when the gel temperature is at least 50° C. and the monomer conversion is not more than 90 mol %, and also to a process for producing hygiene articles.
Abstract:
Swellable hydrogel-forming polymers having high permeability Swellable hydrogel-forming polymer comprising at least one hydrophilic polymer of dendritic structure and at least one water-insoluble phosphate, a process for preparing the swellable hydrogel-forming polymer and also its use in hygiene articles.
Abstract:
To prepare superabsorbents with a low residual monomer content, a salt of urea with an inorganic acid is added to the monomer mixture before or during the polymerization or to the polymer after the polymerization but before a heat treatment which follows the polymerization.
Abstract:
Superabsorbents comprising a compound of the formula (I) in which M is a hydrogen atom, an ammonium ion, a monovalent metal ion or one equivalent of a divalent metal ion of groups 1, 2, 8, 9, 10, 12 or 14 of the periodic table of the elements; R1 is OH or NR4R5 where R4 and R5 are each independently H or C1-C6-alkyl; R2 is H or an alkyl, alkenyl, cycloalkyl or aryl group, where this group optionally has 1, 2 or 3 substituents which are each independently selected from C1-C6-alkyl, OH, O—C1-C6-alkyl, halogen and CF3; and R3 is COOM, SO3M, COR4, CONR4R5 or COOR4, where M, R4 and R5 are each as defined above or, when R2 is aryl which is optionally substituted as specified above, are also H, salts thereof or mixtures of such compounds and/or salts thereof, exhibit improved stability to discoloration in the course of storage under elevated temperatures and/or elevated air humidity.
Abstract:
The present invention relates to odor-inhibiting compositions comprising water-absorbing polymer particles and metal peroxides, and to the production thereof.
Abstract:
The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
Abstract:
The present invention provides compounds of formula (I); pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.