公开(公告)号：US08154714B2

公开(公告)日：2012-04-10

申请号：US12266379

申请日：2008-11-06

Applicant: Michael D. Furtaw ,  Robert D. Eckles ,  Georgiy G. Burba ,  Dayle K. McDermitt ,  Jonathan M. Welles

Inventor： Michael D. Furtaw ,  Robert D. Eckles ,  Georgiy G. Burba ,  Dayle K. McDermitt ,  Jonathan M. Welles

IPC: G01N21/00

CPC classification number: G01N21/3504 ,  G01K13/02 ,  G01K2013/024 ,  G01N1/2247 ,  G01N21/05 ,  G01N2201/0245

Abstract: Gas analyzer systems and methods for measuring concentrations of gasses and in particular dry mole fraction of components of a gas. The systems and method allow for rapid measurement of the gas density and/or dry mole fraction of gases for a number of environmental monitoring applications, including high speed flux measurements. A novel coupling design allows for tool-free removal of a cell enclosing a flow path to enable in field cleaning of optical components.

公开(公告)号：US20120050730A1

公开(公告)日：2012-03-01

申请号：US13318500

申请日：2010-04-27

Applicant: Georg Moll ,  Dominik Rabus ,  Michael Winkler

Inventor： Georg Moll ,  Dominik Rabus ,  Michael Winkler

IPC: G01N21/05

CPC classification number: G01N21/05 ,  G01N21/53 ,  G01N21/532 ,  G01N21/534 ,  G01N2021/054 ,  G01N2021/1734 ,  G01N2021/1744 ,  G01N2201/0245

Abstract: A modular optical sensor system for fluid media has a measuring module which includes an exchangeable fluid chamber and an exchangeable optic holder. The fluid chamber has an inlet and an outlet as well as a measurement space for the fluid medium. The optic holder has at least one optical transmitter and at least one optical receiver. The optic holder is inserted within the measuring module relative to the fluid chamber in such a way that the radiation emitted by the optical transmitter traverses the measurement space for the fluid medium in the fluid chamber and impinges on the optical receiver.

Abstract translation: 用于流体介质的模块化光学传感器系统具有测量模块，其包括可更换的流体室和可更换的光学座。 流体室具有入口和出口以及用于流体介质的测量空间。 光学保持器具有至少一个光发射器和至少一个光接收器。 光学保持器相对于流体室以这样的方式插入测量模块内，使得由光学发射器发射的辐射穿过用于流体室中的流体介质的测量空间并撞击在光学接收器上。

公开(公告)号：US20110223681A1

公开(公告)日：2011-09-15

申请号：US13122560

申请日：2009-09-28

Applicant: Ulrich Lundgreen ,  Aria Farjam ,  Rolf Uthemann ,  Andreas Mitreiter ,  Isabel Huenig ,  Markus Lenhard ,  Rainer Froemel ,  Hans-Joachim Kumpch

Inventor： Ulrich Lundgreen ,  Aria Farjam ,  Rolf Uthemann ,  Andreas Mitreiter ,  Isabel Huenig ,  Markus Lenhard ,  Rainer Froemel ,  Hans-Joachim Kumpch

IPC: G01N33/18 ,  G01N21/00 ,  G01N27/26

CPC classification number: G01N33/1893 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0838 ,  B01L2400/0475 ,  G01N21/3151 ,  G01N21/78 ,  G01N27/4167 ,  G01N27/4168 ,  G01N33/1886 ,  G01N2201/0245

Abstract: A mobile water analyzing system for determining an analyte in a water sample includes a basic unit and a test element configured to be inserted into the basic unit. The test element includes a sample line with an inlet opening configured to receive the water sample, a measuring section forming a measuring track and configured to allow the determination of an analyte, a pump opening, and a key reagent disposed inside the sample line. The basic unit includes a test element receptacle configured to hold the inserted test element, an analyzer with an analyzer measuring track formed by the measuring section, and a pump actuator cooperatively connected with the pump opening.

Abstract translation: 用于确定水样品中的分析物的移动水分析系统包括基本单元和被配置为插入到基本单元中的测试元件。 测试元件包括具有被配置为接收水样本的入口开口的样品管线，形成测量轨道的测量部分，并且被配置为允许确定分析物，泵开口和设置在样品管线内部的密钥试剂。 基本单元包括被配置为保持插入的测试元件的测试元件插座，具有由测量部分形成的分析器测量轨迹的分析器和与泵开口协作连接的泵致动器。

公开(公告)号：US20090141272A1

公开(公告)日：2009-06-04

申请号：US12321830

申请日：2009-01-26

Applicant: Mark F. Oldham ,  Eugene F. Young

Inventor： Mark F. Oldham ,  Eugene F. Young

IPC: G01J3/28

CPC classification number: G01N21/6486 ,  B01L3/5085 ,  B01L7/52 ,  C12Q2545/101 ,  G01N21/274 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/0245 ,  G01N2201/0628 ,  G01N2201/0635 ,  Y10S435/808 ,  Y10S435/809

Abstract: An instrument is provided that can monitor nucleic acid sequence amplification reactions, for example, PCR amplification of DNA and DNA fragments. The instrument includes a multi-notch filter disposed along one or both of an excitation beam path and an emission beam path. Methods are also provided for monitoring nucleic acid sequence amplifications using an instrument that includes a multi-notch filter disposed along a beam path.

Abstract translation: 提供了可以监测核酸序列扩增反应的仪器，例如DNA和DNA片段的PCR扩增。 仪器包括沿激发光束路径和发射光束路径中的一个或两个设置的多陷波滤波器。 还提供了使用包括沿着光束路径设置的多陷波滤波器的仪器来监测核酸序列扩增的方法。

公开(公告)号：US20090103077A1

公开(公告)日：2009-04-23

申请号：US12256786

申请日：2008-10-23

Applicant: Charles W. Robertson, JR. ,  Joel B. Hansen ,  Dale Heintzelman ,  Thomas A. Tokash ,  Paul S. Zdinak ,  Damian W. Ashmead ,  Jonathan Pundt

Inventor： Charles W. Robertson, JR. ,  Joel B. Hansen ,  Dale Heintzelman ,  Thomas A. Tokash ,  Paul S. Zdinak ,  Damian W. Ashmead ,  Jonathan Pundt

IPC: G01J1/04

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0235 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/32 ,  G01N21/6445 ,  G01N21/645 ,  G01N2021/035 ,  G01N2021/6471 ,  G01N2201/0245

Abstract: A photometer is provided with modular lighting units wherein each lighting unit includes one or more light emitters. A user may select a desired lighting unit and install it within a photometer base unit, and thereafter activate one or more of the emitters (which may emit light of different wavelengths) to illuminate a specimen. The light provided by the specimen in response can then be captured at a detector, and analyzed to provide an indication of the specimen's characteristics. Different lighting units may optionally include one or more input light adapters (filters or polarizers which modify the light provided by the emitter(s) to the specimen), and/or one or more output light adapters (filters or polarizers which modify the light provided by the specimen to the detector). Users may therefore select lighting units with emitters and light adapters which are particularly suited for detection/analysis of particular specimens and/or components therein.

Abstract translation: 光度计设置有模块化照明单元，其中每个照明单元包括一个或多个发光器。 用户可以选择所需的照明单元并将其安装在光度计基座单元内，然后激活一个或多个发射器（其可以发射不同波长的光）以照射样本。 然后可以在检测器处捕获由样品提供的光，并分析以提供样品特征的指示。 不同的照明单元可以可选地包括一个或多个输入光适配器（将由发射器提供的光改变为样本的滤光器或偏振器）和/或一个或多个输出光适配器（改变所提供的光的滤光器或偏振器 通过样品到检测器）。 因此，用户可以选择具有发射器和光适配器的照明单元，其特别适于检测/分析其中的特定样品和/或部件。

公开(公告)号：US07283245B2

公开(公告)日：2007-10-16

申请号：US10760438

申请日：2004-01-20

Applicant: Caibin Xiao ,  Scott M. Boyette ,  Radislav A. Potyrailo

Inventor： Caibin Xiao ,  Scott M. Boyette ,  Radislav A. Potyrailo

IPC: G01N21/27 ,  G01N21/47 ,  G01N21/00 ,  G06F19/00

CPC classification number: G01N21/7703 ,  G01N21/253 ,  G01N21/272 ,  G01N21/274 ,  G01N21/314 ,  G01N21/552 ,  G01N21/8483 ,  G01N2021/7783 ,  G01N2021/8488 ,  G01N2201/0221 ,  G01N2201/0245 ,  G01N2201/0461 ,  G01N2201/122

Abstract: A portable system and method for measuring the concentration of multiple chemical or biological substances where an onsite analysis of such substances is needed. The new and original handheld sensor system uses a disposable optical test element and a spectroscopic detector that measures the test element response to specific analytes through a change in light absorbance, luminescence, and other forms of light-based response. In this way, reflection light intensities indicative of the test element response can be used to measure the concentration of the target analytes. The sensor system is also capable of being interfaced to an information processing unit or computer so that analytical data can be manipulated or stored electronically.

Abstract translation: 用于测量需要对这些物质进行现场分析的多种化学或生物物质的浓度的便携式系统和方法。 新的和原始的手持传感器系统使用一次性光学测试元件和光谱检测器，其通过光吸收，发光和其他形式的基于光的响应的变化来测量测试元件对特定分析物的响应。 以这种方式，可以使用指示测试元件响应的反射光强度来测量目标分析物的浓度。 传感器系统还能够连接到信息处理单元或计算机，从而可以电子地操纵或存储分析数据。

公开(公告)号：US20070218454A1

公开(公告)日：2007-09-20

申请号：US11378760

申请日：2006-03-16

Applicant: Reid Brennen ,  Timothy Beerling ,  Hongfeng Yin ,  Kevin Killeen

Inventor： Reid Brennen ,  Timothy Beerling ,  Hongfeng Yin ,  Kevin Killeen

IPC: C12Q1/00

CPC classification number: G01N21/0303 ,  G01N2021/036 ,  G01N2201/0245

Abstract: The present invention relates to an optical detection cell for micro-fluidics. The detection cell provides a first layer, a detection cell layer contacting the first layer, a third layer contacting the detection cell layer and a detection channel defined through the detection cell to serve as a light path for receiving light for detecting a molecule Methods of detecting molecules and making the detection cell are also disclosed

Abstract translation: 本发明涉及一种用于微流体学的光学检测单元。 检测单元提供第一层，接触第一层的检测单元层，接触检测单元层的第三层和通过检测单元定义的检测通道，用作接收用于检测分子的光的光路。检测方法 分子和制备检测电池也被公开

公开(公告)号：US20070182965A1

公开(公告)日：2007-08-09

申请号：US11529694

申请日：2006-09-28

Applicant: Leonard Kamlet ,  Martin Spartz ,  Peter Rosenthal

Inventor： Leonard Kamlet ,  Martin Spartz ,  Peter Rosenthal

IPC: G01N21/61 ,  G01N21/00

CPC classification number: G01N21/05 ,  G01N21/3504 ,  G01N2201/0245

Abstract: A modular system for gas analysis has a first gas cell that receives and passes at least a portion of an infrared light beam through at least a portion of the first gas cell. A second gas cell disposed proximal to the first gas cell receives and passes at least a portion of the infrared light beam from the first gas cell through at least a portion of the second gas cell. At least a portion of the first gas cell and at least a portion of the second gas cell define a light path having an effective length. The system includes a means for adjusting the effective length of the light path to vary a property of the infrared light beam. Methods of making a variable effective length light path and methods of making a gas detector are also disclosed.

Abstract translation: 用于气体分析的模块化系统具有接收并使至少一部分红外光束通过至少一部分第一气室的第一气室。 设置在第一气体单元附近的第二气室容纳并使来自第一气室的至少一部分红外光束通过第二气室的至少一部分。 第一气室的至少一部分和第二气室的至少一部分限定具有有效长度的光路。 该系统包括用于调节光路的有效长度以改变红外光束的性质的装置。 还公开了制造可变有效长度光路的方法和制造气体检测器的方法。

公开(公告)号：US07183103B2

公开(公告)日：2007-02-27

申请号：US10370846

申请日：2003-02-20

Applicant: Michael R. Gambini ,  Susan Atwood Stone, legal representative ,  Judith K. Atwood, legal representative ,  Eugene F. Young ,  Edward J. Lakatos ,  Anthony L. Cerrone

Inventor： John G. Atwood, deceased

IPC: C12M1/34

CPC classification number: G01N21/6428 ,  B01L3/5085 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/1811 ,  C12Q1/686 ,  C12Q2545/101 ,  G01N21/274 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/0245 ,  G01N2201/06113 ,  G01N2201/0628 ,  G01N2201/0635 ,  G01N2201/0636 ,  G01N2201/068 ,  C12Q2563/107

Abstract: An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.

公开(公告)号：US07118713B2

公开(公告)日：2006-10-10

申请号：US10821441

申请日：2004-04-09

Applicant: David A. Brock ,  Donald R. Hesser ,  Gary H. Krauth ,  Jack L. Zuidema ,  David L. Boger ,  Kevin J. Sheldrake

Inventor： David A. Brock ,  Donald R. Hesser ,  Gary H. Krauth ,  Jack L. Zuidema ,  David L. Boger ,  Kevin J. Sheldrake

IPC: B01L9/00

CPC classification number: G01N21/8483 ,  B01L9/52 ,  B01L2300/0825 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/4738 ,  G01N21/78 ,  G01N2021/0325 ,  G01N2201/0245 ,  G01N2201/12792

Abstract: A tray assembly for use with an apparatus adapted to inspect a liquid sample, including a support tray insertable within an inspection location within the liquid sample inspection apparatus so that a light source of the apparatus illuminates a liquid sample carried on the support tray and a detector of the apparatus receives light from the liquid sample when the support tray is positioned at the inspection location, and an insert supported within the support tray and having a first surface adapted to receive a first type of liquid carrier and a second surface adapted to receive a second type of liquid carrier different from the first type of liquid carrier.

Abstract translation: 一种用于与适于检查液体样品的设备一起使用的托盘组件，包括可插入在液体样品检查设备内的检查位置内的支撑托盘，使得设备的光源照亮承载在支撑托盘上的液体样品和检测器 当所述支撑托盘位于所述检查位置时，所述设备从所述液体样品接收光，以及插入件，其被支撑在所述支撑托盘内并且具有适于接纳第一类型的液体载体的第一表面和适于接收 第二类液体载体不同于第一类液体载体。