公开(公告)号：US20240230406A1

公开(公告)日：2024-07-11

申请号：US18393636

申请日：2023-12-21

Applicant: National Central University

Inventor： Fan-Ching Chien ,  Kun-Yu Lai ,  Ching-Lung Luo

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18

CPC classification number: G01J3/2823 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/027 ,  G01J3/06 ,  G01J3/10 ,  G01J3/18 ,  G01J2003/064 ,  G01J2003/069 ,  G01J2003/1213 ,  G01J2003/2826

Abstract: The present invention provides a wide-filed spectral imaging system including a laser generator, a wavelength adjustment module, an objective lens, and a single-pixel imaging and a spectral separating module. The laser generator is configured to generate a laser excitation beam. The wavelength adjustment module is configured to disperse the laser excitation beam into a plurality of beams of different wavelengths. The objective lens is configured to focus the plurality of beams of different wavelengths on a sample to excite molecules under test in the sample and generate an emission light. The single-pixel imaging and spectral separating module is configured to generate a series of patterns and modulate the emission light with the series of patterns to generate a diffracted beam. The single-pixel imaging and spectral separating module further disperses the wavelength of the diffracted beam, collects light signals of the expanded diffracted beam, and performs a spectral image reconstruction.

公开(公告)号：US12026900B2

公开(公告)日：2024-07-02

申请号：US16234360

申请日：2018-12-27

Applicant: Cilag GmbH International

Inventor： Joshua D. Talbert ,  Donald M. Wichern

IPC: G06T7/521 ,  A61B1/00 ,  A61B1/04 ,  A61B1/045 ,  A61B1/05 ,  A61B1/06 ,  G01J3/02 ,  G01J3/10 ,  G01J3/28 ,  G02B23/24 ,  H04N5/265 ,  H04N5/272 ,  H04N13/239 ,  H04N23/10 ,  H04N23/13 ,  H04N23/45 ,  H04N23/56 ,  H04N23/74 ,  H04N23/741 ,  H04N23/84 ,  H04N25/53 ,  H04N25/533 ,  H04N23/50

CPC classification number: G06T7/521 ,  A61B1/0005 ,  A61B1/00066 ,  A61B1/00096 ,  A61B1/00186 ,  A61B1/00193 ,  A61B1/043 ,  A61B1/045 ,  A61B1/05 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0653 ,  A61B1/0661 ,  G01J3/027 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/2823 ,  G02B23/2461 ,  G02B23/2484 ,  H04N5/265 ,  H04N5/272 ,  H04N13/239 ,  H04N23/125 ,  H04N23/13 ,  H04N23/45 ,  H04N23/56 ,  H04N23/74 ,  H04N23/741 ,  H04N23/84 ,  H04N25/53 ,  H04N25/533 ,  G01J2003/2826 ,  G06T2207/10024 ,  G06T2207/10028 ,  G06T2207/10068 ,  G06T2207/30004 ,  H04N23/555

Abstract: An endoscopic imaging system for use in a light deficient environment includes an imaging device having a tube, one or more image sensors, and a lens assembly including at least one optical elements that corresponds to the one or more image sensors. The endoscopic system includes a display for a user to visualize a scene and an image signal processing controller. The endoscopic system includes a light engine having an illumination source generating one or more pulses of electromagnetic radiation and a lumen transmitting one or more pulses of electromagnetic radiation to a distal tip of an endoscope.

公开(公告)号：US12005451B2

公开(公告)日：2024-06-11

申请号：US17256348

申请日：2019-06-28

Applicant: RAB MICROFLUIDICS RESEARCH AND DEVELOPMENT COMPANY LIMITED

Inventor： Oluwarotimi Alabi ,  Surakat Kudehunbu ,  Barry James Warden ,  Stephen McIntosh

IPC: F01M11/10 ,  B01L3/00 ,  G01J3/10 ,  G01N33/28

CPC classification number: B01L3/502753 ,  F01M11/10 ,  G01J3/10 ,  G01N33/2858 ,  G01N33/2888 ,  B01L2300/0681 ,  F01M2011/1413 ,  F01M2011/144

Abstract: The invention provides a microfluidic system for monitoring the condition of lubricating oil. The microfluidic system comprises a microfluidic device with at least one microchannel (40) configured to allow a sample of lubricating oil (52a) to pass therethrough as a laminar flow. The device has at least one separating device (41) configured to selectively separate at least one component (54b) from the lubricating oil (52a) in the fluid flow. The microfluidic system also comprises a detector device (20, 22) configured to detect the presence and/or measure at least one property of the at least one component passing through the microfluidic device after separation in the microchannel (40).

公开(公告)号：US11988557B2

公开(公告)日：2024-05-21

申请号：US17545106

申请日：2021-12-08

Applicant: BATTELLE SAVANNAH RIVER ALLIANCE, LLC

Inventor： Kimberly Alicia Strange Fessler ,  Steven Michael Serkiz

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/10 ,  G01N21/65

CPC classification number: G01J3/44 ,  G01J3/10 ,  G01N21/65 ,  G01J3/0218

Abstract: Methods and systems are described for use in determination of the presence, type (static or AC), direction, and/or strength of an electric field. Methods include examination of a gaseous sample to determine the presence of perturbation effects brought about by dielectrophoretic forces acting on components of the gaseous sample, and thereby, to identify the presence of an electric field. Examination of a gaseous sample can include Raman spectroscopy. A gaseous sample can be analyzed to determine the presence of molecular polarization due to an induced dipole on a polarizable molecule.

公开(公告)号：US20240151582A1

公开(公告)日：2024-05-09

申请号：US18483765

申请日：2023-10-10

Applicant: MGI Tech Co., Ltd.

Inventor： Paul Lundquist ,  Razvan Chirita

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/10

CPC classification number: G01J3/2803 ,  G01J3/0208 ,  G01J3/10

Abstract: Systems and methods for immersion imaging of a flowcell. In one example, an imaging system includes liquid ports in leading and trailing positions relative to a scanned imaging objective. The leading liquid port dispenses an immersion liquid into a space between the distal end of the imaging objective and the flowcell's cover, with the trailing liquid port collecting the immersion liquid. In another example, an imaging system includes a flowcell with a cover that is moveable relative a substrate. The system is configured to move the imaging objective and flowcell cover as a unit relative to the flowcell substrate.

公开(公告)号：US11967799B2

公开(公告)日：2024-04-23

申请号：US15508889

申请日：2015-08-28

Applicant: PILOT PHOTONICS LIMITED

Inventor： Jules Braddell ,  Frank Smyth

IPC: H01S5/065 ,  G01J3/10 ,  G01J3/42 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/39 ,  G01N21/45 ,  H01S5/00 ,  H01S5/042 ,  H01S5/10 ,  H01S5/40

CPC classification number: H01S5/0656 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3504 ,  H01S5/0064 ,  H01S5/0085 ,  H01S5/0427 ,  H01S5/1096 ,  H01S5/4006 ,  G01N2021/3133 ,  G01N2021/3148 ,  G01N2021/399 ,  G01N2021/451 ,  G01N2201/0612

Abstract: A method of performing spectroscopic measurements provides an optical frequency comb, and directs the comb through or at a sample. The optical frequency comb is generated by gain switching a laser diode constructed from Gallium Nitride and related materials. Various techniques are described for manipulating the comb source to achieve desired benefits for spectroscopy.

公开(公告)号：US11957460B2

公开(公告)日：2024-04-16

申请号：US16777855

申请日：2020-01-30

Applicant: LifePlus Inc

Inventor： Kevin Hazen ,  Alan Abul-Haj ,  Roxanne Abul-Haj ,  Christopher Slawinski ,  Alodeep Sanyal ,  Benjamin Mbouombouo

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01J3/10 ,  G01N33/49

CPC classification number: A61B5/1455 ,  A61B5/0022 ,  A61B5/0051 ,  A61B5/0053 ,  A61B5/14532 ,  A61B5/6824 ,  A61B5/6832 ,  G01J3/10 ,  G01N33/49 ,  A61B5/0004 ,  A61B5/7264 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/046 ,  G01J2003/102 ,  G01J2003/106

Abstract: The invention comprises a method and apparatus for sampling a common tissue volume and/or a common skin layer skin of a person as a part of noninvasively determining an analyte property with an analyzer including: a set of detectors at least partially embedded in a probe housing, the probe housing comprising a sample side surface, the detectors including a first and second range of detection zones of differing radial distances from a first illumination zone and second illumination zone, respectively coupled to separate sources, with surface paths between the sources and detectors overlapping a common skin area during use.

公开(公告)号：US20240094130A1

公开(公告)日：2024-03-21

申请号：US18214507

申请日：2023-06-26

Applicant: SHIMADZU CORPORATION

Inventor： Fumiya KATSUTANI ,  Tomoki SASAYAMA ,  Tomoyo TAO ,  Atsuhiko OTAGURO ,  Ryuta SHIBUTANI ,  Hisato FUKUDA

IPC: G01N21/65 ,  G01J3/02 ,  G01J3/10 ,  G01J3/44 ,  G02B21/06

CPC classification number: G01N21/65 ,  G01J3/0208 ,  G01J3/10 ,  G01J3/44 ,  G02B21/06 ,  G01J2003/102

Abstract: A Raman infrared compound microscope device includes: a first light source that generates laser light; a second light source that generates infrared light; a third light source that generates visible light; and a first optical system. The first optical system orients the visible light having reached the first optical system in different directions between when performing a Raman analysis using Raman light generated from a sample by irradiation of the laser light and when performing a first infrared analysis using the infrared light having passed through the sample.

公开(公告)号：US20240060895A1

公开(公告)日：2024-02-22

申请号：US18496681

申请日：2023-10-27

Applicant: Illumina, Inc.

Inventor： Rui JIANG ,  Joseph PINTO

IPC: G01N21/64 ,  C12Q1/6869 ,  G01J3/10 ,  G02B27/09

CPC classification number: G01N21/6428 ,  C12Q1/6869 ,  G01J3/10 ,  G01N21/6452 ,  G01N21/6456 ,  G02B27/0994 ,  G01N2021/6419 ,  G01N2021/6439 ,  G01N2021/6463 ,  G01N2201/0638 ,  G01N2201/08 ,  G01N2201/0806 ,  H01L27/14612

Abstract: There is set forth herein a light energy exciter that can include one or more light sources. A light energy exciter can emit excitation light directed toward a detector surface that can support biological or chemical samples.

公开(公告)号：US11892281B2

公开(公告)日：2024-02-06

申请号：US17655899

申请日：2022-03-22

Applicant: Otsuka Electronics Co., Ltd.

Inventor： Shiro Kawaguchi ,  Kazuya Nakajima ,  Hayato Takizawa ,  Goro Maeda

IPC: G01B11/06 ,  G01J3/02 ,  G01J3/10 ,  G01B5/00 ,  G01N21/27 ,  G01B9/02055 ,  G01J3/28 ,  G01N21/25 ,  G01B21/04

CPC classification number: G01B11/0625 ,  G01B5/0014 ,  G01B9/0207 ,  G01B11/06 ,  G01B11/0675 ,  G01B21/045 ,  G01J3/02 ,  G01J3/027 ,  G01J3/0232 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/28 ,  G01N21/25 ,  G01N21/274 ,  G01N21/276 ,  G01J2003/2836

Abstract: An optical measurement system includes a light source, a spectroscopic detector, a reference sample, a switching mechanism that switches between a first optical path through which a sample to be measured is irradiated with light from the light source and light produced at the sample is guided to the spectroscopic detector and a second optical path through which the reference sample is irradiated with light from the light source and light produced at the reference sample is guided to the spectroscopic detector, and a processing unit that calculates, by performing correction processing based on change between a first detection result at first time and a second detection result at second time, a measurement value of the sample from a third detection result provided from the spectroscopic detector as a result of irradiation of the sample with light from the light source at third time temporally proximate to the second time.