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111.
公开(公告)号:US20250163408A1
公开(公告)日:2025-05-22
申请号:US18743720
申请日:2024-06-14
Inventor: Jeong Wook LEE , Yun-nam CHOI , Dong Hyeon KIM , Seong Beom LEE
Abstract: The present invention relates to a genetic biocontainment technology to prevent theft or misuse of biological resources (e.g., nucleic acid molecule, plasmid or microbial strain containing the nucleic acid molecule, or sequence information associated with the nucleic acid molecule) using a quadruplet codon and decoding system thereof. In particular, the present invention relates to a system or a microbial strain comprising a nucleic acid molecule in which a triplet codon encoding a specific amino acid in a nucleic acid sequence has been replaced with a quadruplet codon, wherein genetic biocontainment occurs in an environment where tRNA for the quadruplet codon does not exist, and a method using the same. The present invention also relates to a biocontainment method to protect sequence information using a quadruplet codon.
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公开(公告)号:US20250137793A1
公开(公告)日:2025-05-01
申请号:US18929890
申请日:2024-10-29
Applicant: HYUNDAI MOTOR COMPANY , KIA CORPORATION , POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventor: Harn Song Lee , Seok Ki Hong , Hwan Jo Yu , Jun Su Cho
Abstract: A device for controlling a vehicle includes a navigation system that acquires big data including a point of interest (POI) with a visit history of a requestor who has requested a place recommendation, and a processor that performs preprocessing on the big data for learning acquired in advance to generate input data, trains a POI recommendation model based on the input data, and inputs the big data into the POI recommendation model that has been trained to generate at least one place the requestor is expected to visit.
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公开(公告)号:US12278750B1
公开(公告)日:2025-04-15
申请号:US18511886
申请日:2023-11-16
Inventor: Hwang Jun Song , Seung Gyu Ji
IPC: H04L43/0864 , H04L67/104
Abstract: Provided is a system and method for estimating an end-to-end delay between blockchain nodes in peer-to-peer (P2P) networks. The system includes a coordinate system construction unit configured to designate an origin node and anchor nodes among participating nodes having a distributed ledger of P2P networks, construct a first coordinate system of a predetermined dimension by exchanging control messages between the origin node and the anchor nodes and the participating nodes, and construct a second coordinate system of another predetermined dimension and a dimension determination unit configured to determine a dimension to be applied to the current P2P networks by comparing dimension-specific delays or control message overheads of the first coordinate system and the second coordinate system.
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114.
公开(公告)号:US20250109383A1
公开(公告)日:2025-04-03
申请号:US18834936
申请日:2023-01-04
Applicant: POSTECH Research and Business Development Foundation , PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
Inventor: Dong-Woo CHO , Byoung Soo KIM , Won-Woo CHO , Min Jun AHN
Abstract: The present invention relates to a method for producing an adipose model through environmental control and an adipose model created using same, the method comprising the steps of: providing a first bioink, which is cell-unfriendly; creating a bath suspension with a predetermined volume by using the first bioink; providing a second bioink comprising preadipocytes; 3Dprinting the second bioink in the bath suspension so as to produce an adipose model; and culturing the bath suspension in which the adipose model is disposed. The method for producing an adipose model through environmental control and the adipose model created using same, according to the present disclosure, form environments for a 3D-printed adipose model, and limit the proliferation area of adipose cells and induce the differentiation thereof, and thus can maximize similarity with actual adipose tissues.
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公开(公告)号:US20250092121A1
公开(公告)日:2025-03-20
申请号:US18576832
申请日:2022-03-28
Inventor: Cheol Sang HWANG , Da Som KIM , Jeong Mok KIM , Ok Hee SEOK
Abstract: The present invention relates to a novel antigen peptide and, more specifically, the antigen peptide is for preparing an antibody capable of specifically detecting formyl-methionine. It has been identified that an antibody prepared using an antigen peptide for the preparation of a formyl-methionine-specific antibody, according to the present invention, has excellent antigen-binding ability at peptide and protein levels and has excellent antigen-binding ability even under a condition in which intracellular formylated protein expression changes. Therefore, an antigen peptide of the present invention can be effectively used in the preparation of antibodies universally recognizing peptides and proteins having formyl-methionine.
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公开(公告)号:US20250077855A1
公开(公告)日:2025-03-06
申请号:US18817862
申请日:2024-08-28
Inventor: Seyoung KIM , Seungkun KIM , Jeonghoon SON
Abstract: The present disclosure relates to a double gate neuromorphic memory device and a manufacturing method thereof. The double gate neuromorphic memory device is an electrochemical device, and includes a bottom gate provided on an upper portion of a semiconductor substrate, a channel area surrounding the upper portion and side surfaces of the bottom gate, a source electrode and a drain electrode provided in contact with both sides of the channel area, and a top gate provided on an upper portion of a channel area between the source electrode and the drain electrode.
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公开(公告)号:US20250074944A1
公开(公告)日:2025-03-06
申请号:US18796506
申请日:2024-08-07
Inventor: Joongoo LEE , Kanghun LEE
Abstract: Non-canonical substrates-acylated tRNA, introduction of non-canonical substrates into a peptide using ribosome catalysis, and method of preparing pharmacologically active motifs are disclosed. The present invention relates to acylated tRNA and introduction of pharmacologically active motif in peptide using ribosome-mediated catalysis and method that enables the production of a peptide having a cyclic motif without a complicated chemical process on an in vitro protein translation system.
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公开(公告)号:US20250064427A1
公开(公告)日:2025-02-27
申请号:US18723846
申请日:2022-12-02
Inventor: Hyung Ham KIM , Yeonggeun KIM
Abstract: The present invention relates to a position tracking-type ultrasonic blood flow monitoring apparatus that can continuously track the position of a blood vessel by adjusting the rotation angle of an ultrasonic probe module according to the position change of the blood vessel. The present invention may provide a blood flow monitoring apparatus comprising a housing having an opening formed at a bottom surface thereof; a first rotation member rotating around a first axis in the housing; a second rotation member mounted to the first rotation member and rotating around a second shaft; and a probe module mounted to the second rotation member, wherein the probe module rotates together with the first rotation member and the second rotation member according to the rotation of the first rotation member and the second rotation member, and can transmit and receive an ultrasonic signal.
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119.
公开(公告)号:US20250058017A1
公开(公告)日:2025-02-20
申请号:US18721363
申请日:2022-03-14
Inventor: Jin Ah JANG , Hyeon Ji KIM , Seung Hyeon HWANG
Abstract: One embodiment of the present disclosure provides an extracellular matrix-based hybrid ink for 3D printing, the hybrid ink including an extracellular matrix having an amine group and a modified hyaluronic acid introduced with an ethylenically unsaturated bond functional group, in which the extracellular matrix and the modified hyaluronic acid are in a crosslinked state by a chemical bond formed between at least some of amine groups present in the extracellular matrix and the ethylenically unsaturated bond functional group present in the modified hyaluronic acid. According to an embodiment of the present disclosure, the hybrid ink has mechanical properties suitable for 3D printing through chemical crosslinking between the extracellular matrix and modified hyaluronic acid as constituents, and can control the drug release rate by adjusting the chemical crosslinking density.
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公开(公告)号:US12216776B2
公开(公告)日:2025-02-04
申请号:US18700030
申请日:2022-11-10
Applicant: UNIVERSITY OF MARYLAND, COLLEGE PARK , POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventor: Giuliano Scarcelli , Yoon-Ho Kim , Jin-Hun Kim
Abstract: A system for noise-resistant quantum communication using hyperentanglement includes a quantum system that includes a plurality of qubits, a processor, and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the quantum system to access a signal of a quantum system that includes a plurality of qubits and obtain hyperentanglement of the plurality of qubits via an entanglement source. The hyperentanglement of the plurality of qubits is in at least two dimensions, including a first dimension and a second dimension. The instructions, when executed, further cause the quantum system to transmit the hyperentangled plurality of qubits via a communication channel; perform a communication of the signal with the first dimension of the at least two dimensions; and filter results of the communicated signal based on the second dimension of the at least two dimensions.
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