公开(公告)号：US20160248227A1

公开(公告)日：2016-08-25

申请号：US15143653

申请日：2016-05-02

Applicant: TOKYO INSTITUTE OF TECHNOLOGY ,  FUJI XEROX CO., LTD.

Inventor： Fumio KOYAMA ,  Hamed DALIR ,  Takashi KONDO ,  Naoki JOGAN ,  Kazutaka TAKEDA ,  Hideo NAKAYAMA

IPC: H01S5/183 ,  H01S5/343 ,  H01S5/022

CPC classification number: H01S5/1835 ,  H01S5/02284 ,  H01S5/06226 ,  H01S5/1032 ,  H01S5/18302 ,  H01S5/18313 ,  H01S5/18344 ,  H01S5/18394 ,  H01S5/3432

Abstract: A vertical-cavity surface-emitting laser diode includes: a first resonator that has a plurality of semiconductor layers comprising a first current narrowing structure having a first conductive region and a first non-conductor region; a first electrode that supplies electric power to drive the first resonator; a second resonator that has a plurality of semiconductor layers comprising a second current narrowing structure having a second conductive region and a second non-conductive region and that is formed side by side with the first resonator, the second current narrowing structure being formed in same current narrowing layer as the layer where the first current narrowing structure is formed; and a coupling portion as defined herein; and an equivalent refractive index of the coupling portion is smaller than an equivalent refractive index of each of the first resonator and the second resonator.

公开(公告)号：US09425679B2

公开(公告)日：2016-08-23

申请号：US13792993

申请日：2013-03-11

Applicant: OMRON CORPORATION ,  TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Masao Mabuchi ,  Kenji Kobayashi ,  Takao Mizokami ,  Yasuhiro Tsubota ,  Akihiro Funamoto ,  Hideaki Fujita

IPC: H02J5/00 ,  H02M1/12 ,  H02M7/49

CPC classification number: H02M1/126 ,  H02M7/49 ,  Y02E10/56

Abstract: An inverter apparatus comprising a first switch group that is connected to a DC power source and includes a first switch and a second switch connected in series; a capacitor that has one end thereof connected to a first connection point between the first switch and the second switch; a second switch group that is connected in parallel with the capacitor and includes a third switch and a fourth switch that are connected in series; a switch control section that controls an ON/OFF state of the first switch, the second switch, the third switch, and the fourth switch to convert DC voltage from the DC power source into AC voltage and output the AC voltage from a second connection point between the third switch and the fourth switch; and a smoothing circuit that is connected to the second connection point and normalizes a pulse waveform of the AC voltage.

Abstract translation: 一种逆变器装置，包括连接到DC电源的第一开关组，并且包括串联连接的第一开关和第二开关; 电容器，其一端连接到第一开关和第二开关之间的第一连接点; 与电容器并联连接的第二开关组，包括串联连接的第三开关和第四开关; 开关控制部分，其控制第一开关的开/关状态，第二开关，第三开关和第四开关，以将来自直流电源的直流电压转换为交流电压，并从第二连接点输出交流电压 在第三开关和第四开关之间; 以及平滑电路，连接到第二连接点并且对AC电压的脉冲波形进行归一化。

公开(公告)号：US09396396B2

公开(公告)日：2016-07-19

申请号：US14440768

申请日：2013-11-06

Applicant: Tokyo Institute of Technology

Inventor： Osamu Hasegawa ,  Gangchen Hua

IPC: G06K9/00 ,  G01B11/00 ,  G06T7/20 ,  G06K9/46 ,  G06K9/62

CPC classification number: G06K9/00691 ,  G01B11/00 ,  G06K9/00704 ,  G06K9/4671 ,  G06K9/6211 ,  G06K2209/29 ,  G06T7/246 ,  G06T2207/10016

Abstract: A place estimation apparatus performs a place estimation process by using position-invariant feature values extracted by a feature value extraction unit. The feature value extraction unit includes local feature value extraction unit that extracts local feature values from each of input images formed from successively-shot successive images, feature value matching unit that obtains matching between successive input images based on the extracted local feature values, corresponding feature value selection unit that selects matched feature values as corresponding feature values, and position-invariant feature value extraction unit that obtains position-invariant feature values based on the corresponding feature values. The position-invariant feature value extraction unit extracts, from among the corresponding feature values, corresponding feature values whose position change is equal to or less than a predetermined threshold as the position-invariant feature values.

Abstract translation: 位置估计装置通过使用由特征值提取单元提取的位置不变特征值来执行位置估计处理。 特征值提取单元包括局部特征值提取单元，其从连续拍摄的连续图像形成的每个输入图像中提取局部特征值，基于提取的局部特征值获得连续输入图像之间的匹配的特征值匹配单元，相应的特征 选择匹配特征值作为对应特征值的值选择单元，以及基于相应特征值获取位置不变特征值的位置不变特征值提取单元。 位置不变特征值提取单元从相应的特征值中提取位置变化等于或小于预定阈值的相应特征值作为位置不变特征值。

公开(公告)号：US20160202560A1

公开(公告)日：2016-07-14

申请号：US14911097

申请日：2014-08-06

Applicant: TOKYO INSTITUTE OF TECHNOLOGY ,  DIC CORPORATION

Inventor： Motoi Kinoshita ,  Atsushi Shishido ,  Isa Nishiyama

IPC: G02F1/1337 ,  C09K19/56

CPC classification number: G02F1/133788 ,  C08F2/48 ,  C08L101/00 ,  C09K19/56 ,  G02F1/133711 ,  G03H1/02 ,  G03H2001/026 ,  Y10T428/10 ,  Y10T428/1005

Abstract: A photo-alignment material in which an alignment film can be formed parallel to a vibration direction of light and a tilt angle of the alignment film is easily controlled and a photo-alignment method using the photo-alignment material are provided. A photo-alignment material of the present invention contains a photo-responsive substance having a threshold value of responding light intensity.

Abstract translation: 可以容易地控制其中可以平行于光的振动方向和取向膜的倾斜角度形成取向膜的光取向材料，并且提供使用光取向材料的光取向方法。 本发明的光取向材料含有具有响应光强度的阈值的光敏物质。

公开(公告)号：US20160145605A1

公开(公告)日：2016-05-26

申请号：US14786416

申请日：2014-04-23

Applicant: TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Tetsuya KADONOSONO ,  Shinae KONDOH

IPC: C12N15/10 ,  C12N9/10 ,  C07K7/08 ,  C07K7/06 ,  G01N33/68 ,  C07K14/435

CPC classification number: C12N15/1037 ,  C07K7/06 ,  C07K7/08 ,  C07K14/001 ,  C07K14/43595 ,  C07K2319/60 ,  C12N9/1088 ,  C12N15/1034 ,  C12N15/1044 ,  C12N15/1093 ,  C12Q1/37 ,  C12Y205/01018 ,  G01N33/6845 ,  G01N2333/96466

Abstract: The object of the present invention is to provide a method for screening peptide(s) highly specific to a target molecule. The object can be solved by a peptide-presenting protein wherein a peptide is presented in a presentation region consisting of the 131st to 139th amino acids in the amino acid sequence of the SEQ ID NO: 54, wherein the peptide consisting of 4 to 15 amino acids is inserted in the 131st to 139th amino acids sequence, or substituted for any of 1 to 9 amino acid(s) sequence in the 131st to 139th amino acids sequence; and a total length of an amino acid sequence corresponding to the 131st to 139th amino acids sequence is 15 or less.

Abstract translation: 本发明的目的是提供一种筛选对靶分子高度特异性的肽的方法。 该目的可以通过肽呈递蛋白来解决，其中肽在由SEQ ID NO：54的氨基酸序列中的第131个至第139个氨基酸组成的呈递区域中存在，其中由4至15个氨基 将酸插入第131至第139个氨基酸序列，或在第131至139个氨基酸序列中取代1至9个氨基酸序列中的任何一个; 对应于第131〜139位氨基酸序列的氨基酸序列的总长度为15以下。

公开(公告)号：US20160102345A1

公开(公告)日：2016-04-14

申请号：US14882109

申请日：2015-10-13

Applicant: Abbott Japan Co., Ltd. ,  Tokyo Institute Of Technology

Inventor： Ken KOMIYA ,  Makoto KOMORI ,  Toru YOSHIMURA

IPC: C12Q1/68

CPC classification number: C12Q1/682 ,  C12Q1/6844 ,  C12Q2525/113 ,  C12Q2525/131 ,  C12Q2525/185 ,  C12Q2531/119

Abstract: Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide. Also disclosed are methods for detecting a target nucleic acid in a sample in which said sample is contacted, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide and a signal amplifier oligonucleotide. The disclosure also provides compositions and kits comprising such sequence conversion and signal amplifier oligonucleotides.

Abstract translation: 公开了用于检测样品中靶核酸的方法。 所述方法包括在聚合酶和内切核酸酶存在下将所述样品与序列转化寡核苷酸接触。 还公开了用于在聚合酶和内切核酸酶的存在下与序列转化寡核苷酸和信号放大寡核苷酸接触的样品中的靶核酸的检测方法。 本公开还提供了包含这种序列转化和信号放大器寡核苷酸的组合物和试剂盒。

公开(公告)号：US09151739B2

公开(公告)日：2015-10-06

申请号：US14283943

申请日：2014-05-21

Applicant: JNC CORPORATION ,  TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Satoshi Inouye ,  Yuiko Sahara ,  Rie Iimori ,  Takamitsu Hosoya

IPC: C07D487/04 ,  G01N21/76 ,  G01N33/53 ,  C12Q1/66 ,  G01N33/20 ,  G01N33/533 ,  G01N33/535 ,  G01N33/542 ,  G01N33/58

CPC classification number: G01N33/20 ,  C07D487/04 ,  C09B57/00 ,  C12Q1/66 ,  G01N33/533 ,  G01N33/535 ,  G01N33/542 ,  G01N33/581 ,  G01N33/582 ,  G01N2333/90241

Abstract: There has been a need for coelenterazine analogs that exhibit luminescence properties different from those of known coelenterazine analogs. The present invention provides the compound represented by general formula (1).

Abstract translation: 已经需要显示与已知的肠溶丝素类似物的发光性质不同的coelenterazine类似物。 本发明提供由通式（1）表示的化合物。

公开(公告)号：US20150233935A1

公开(公告)日：2015-08-20

申请号：US14705244

申请日：2015-05-06

Applicant: TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Hiroshi HANDA ,  Mamoru HATAKEYAMA ,  Satoshi SAKAMOTO ,  Yusuke MOCHIZUKI ,  Shintaro KAWADA

IPC: G01N33/58 ,  H01F1/09

CPC classification number: G01N33/582 ,  C08J3/12 ,  C08J3/128 ,  C08J2327/12 ,  G01N33/533 ,  G01N33/54326 ,  G01N2458/40 ,  H01F1/06 ,  H01F1/09

Abstract: A method for preparing polymer magnetic particles comprising magnetic particles and a coating polymer layer covering the magnetic particles and containing fluorescent molecules, the method includes swelling a coating polymer layer of the polymer magnetic particles in a non-aqueous solvent-containing and absorbing the fluorescent molecules inside the swelled coating polymer layer, adding water to the non-aqueous solvent in which the polymer magnetic particles adsorbing the fluorescent molecules are present, and removing the non-aqueous solvent by evaporation; where the non-aqueous solvent has affinity with water, a lower boiling point, and a higher vapor pressure than those of water, and the fluorescent molecule is selected from rare earth metal chelate complexes.

Abstract translation: 一种制备包含磁性颗粒的聚合物磁性颗粒和覆盖磁性颗粒并含有荧光分子的涂层聚合物层的方法，该方法包括使聚合物磁性颗粒的涂覆聚合物层溶胀在非水溶剂中并吸收荧光分子 在溶胀的涂料聚合物层的内部，向吸附有荧光分子的聚合物磁性粒子的非水溶剂中加入水，通过蒸发除去非水溶剂; 其中非水溶剂与水具有亲和性，沸点低，蒸气压高于水，荧光分子选自稀土金属螯合物。

公开(公告)号：US20150209696A1

公开(公告)日：2015-07-30

申请号：US14425929

申请日：2013-08-07

Applicant: Hitachi, Ltd. ,  Tokyo Institute of Technology

Inventor： Takuya Kambayashi ,  Kentaro Nakamura

IPC: B01D21/28

CPC classification number: B01D21/283 ,  B01D43/00 ,  B01J19/10 ,  C02F1/36

Abstract: A suspension processing method using ultrasonic waves has problems in that movement of solids in liquid do not follow movement of the sound field. Accordingly, application to a field that requires a high suspension processing performance or a high flow rate process is difficult. In order to achieve the high suspension processing performance, a design of adopting a long and large oscillator and the like is required. A suspension processing device (30) of separating and concentrating a component of solids in suspension (1a) using ultrasonic waves, includes: at least one supply port (32) for supplying the suspension (1a) into the device; a channel (31) through which the suspension flows; at least two outlet ports (33 and 34) for discharging processed suspension (1a); an oscillator (35) for emitting ultrasonic waves; and a reflection plate (36) for reflecting the emitted ultrasonic waves.

Abstract translation: 使用超声波的悬浮处理方法存在的问题在于液体中的固体的运动不跟随声场的移动。 因此，难以应用于需要高悬浮处理性能或高流量处理的领域。 为了实现高悬浮加工性能，需要采用长而大的振荡器等的设计。 使用超声波分离和浓缩悬浮液（1a）中的固体成分的悬浮处理装置（30）包括：用于将悬浮液（1a）供应到装置中的至少一个供给口（32） 悬挂液流过的通道（31）; 至少两个用于排出经处理的悬浮液（1a）的出口（33和34）; 用于发射超声波的振荡器（35）; 以及用于反射发射的超声波的反射板（36）。

公开(公告)号：US20150197823A1

公开(公告)日：2015-07-16

申请号：US14597981

申请日：2015-01-15

Applicant: Abbott Japan Co., Ltd. ,  Tokyo Institute of Technology

Inventor： KEN KOMIYA ,  MAKOTO KOMORI ,  TORU YOSHIMURA

IPC: C12Q1/70 ,  C12Q1/68

CPC classification number: C12Q1/707 ,  C12Q1/682 ,  C12Q1/6844 ,  C12Q1/689 ,  C12Q1/703 ,  C12Q1/706 ,  C12Q2600/158 ,  C12Q2600/178 ,  C12Q2521/301 ,  C12Q2525/301

Abstract: Disclosed are methods for detecting a target nucleic acid in sample, which include contacting the sample with an oligonucleotide having a hairpin structure, where the oligonucleotide includes, in the 5′ to 3′ direction, an arbitrary sequence, an endonuclease recognition site for a nicking reaction, a sequence complementary to the arbitrary sequence, and a sequence complementary to the target nucleic acid; a polymerase; and an endonuclease capable of nicking the endonuclease recognition site. The disclosure also provides compositions and kits comprising an oligonucleotide having a hairpin structure, where the oligonucleotide includes, in the 5′ to 3′ direction an arbitrary sequence, an endonuclease recognition site for a nicking reaction, a sequence complementary to the arbitrary sequence, and a sequence complementary to a target nucleic acid.

Abstract translation: 公开了用于检测样品中靶核酸的方法，其包括使样品与具有发夹结构的寡核苷酸接触，其中寡核苷酸在5'至3'方向上包含任意序列，用于切口的内切核酸酶识别位点 反应，与任意序列互补的序列和与靶核酸互补的序列; 聚合酶 和能够切割内切核酸酶识别位点的核酸内切酶。 本公开还提供了包含具有发夹结构的寡核苷酸的组合物和试剂盒，其中寡核苷酸在5'至3'方向上包含任意序列，用于切口反应的内切核酸酶识别位点，与任意序列互补的序列，以及 与靶核酸互补的序列。