公开(公告)号：US20150233935A1

公开(公告)日：2015-08-20

申请号：US14705244

申请日：2015-05-06

Applicant: TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Hiroshi HANDA ,  Mamoru HATAKEYAMA ,  Satoshi SAKAMOTO ,  Yusuke MOCHIZUKI ,  Shintaro KAWADA

IPC: G01N33/58 ,  H01F1/09

CPC classification number: G01N33/582 ,  C08J3/12 ,  C08J3/128 ,  C08J2327/12 ,  G01N33/533 ,  G01N33/54326 ,  G01N2458/40 ,  H01F1/06 ,  H01F1/09

Abstract: A method for preparing polymer magnetic particles comprising magnetic particles and a coating polymer layer covering the magnetic particles and containing fluorescent molecules, the method includes swelling a coating polymer layer of the polymer magnetic particles in a non-aqueous solvent-containing and absorbing the fluorescent molecules inside the swelled coating polymer layer, adding water to the non-aqueous solvent in which the polymer magnetic particles adsorbing the fluorescent molecules are present, and removing the non-aqueous solvent by evaporation; where the non-aqueous solvent has affinity with water, a lower boiling point, and a higher vapor pressure than those of water, and the fluorescent molecule is selected from rare earth metal chelate complexes.

Abstract translation: 一种制备包含磁性颗粒的聚合物磁性颗粒和覆盖磁性颗粒并含有荧光分子的涂层聚合物层的方法，该方法包括使聚合物磁性颗粒的涂覆聚合物层溶胀在非水溶剂中并吸收荧光分子 在溶胀的涂料聚合物层的内部，向吸附有荧光分子的聚合物磁性粒子的非水溶剂中加入水，通过蒸发除去非水溶剂; 其中非水溶剂与水具有亲和性，沸点低，蒸气压高于水，荧光分子选自稀土金属螯合物。