公开(公告)号：US20100217121A1

公开(公告)日：2010-08-26

申请号：US12680266

申请日：2008-09-19

Applicant: Shigeru Nemoto

Inventor： Shigeru Nemoto

IPC: A61B6/00 ,  G06N5/02 ,  G05D7/06 ,  G05D11/13 ,  G06K9/00

CPC classification number: A61B6/481 ,  A61B5/201 ,  A61B6/4494 ,  A61B6/487

Abstract: A liquid injector acquires personal condition data originating from a patient, before executing injection of a medical liquid, and a function decision unit decides whether the patient has renal dysfunction based on the acquired personal condition data. Accordingly, such arrangement can be made that in the case where the patient is not decided to have renal dysfunction the liquid injection is executed without announcing an alert, and that in the contrary case the alert is announced and the liquid injection is suspended. Thus, the liquid injector allows easily and surely preventing improper injection of the liquid such as a contrast medium to a patient with renal dysfunction.

Abstract translation: 液体注射器在执行医用液体的注入之前获取源自病人的个人状况数据，并且功能决定单元基于获取的个人状态数据来判定患者是否具有肾功能障碍。 因此，可以进行这样的配置：在患者不被判定为具有肾功能障碍的情况下，在不通知警报的情况下执行液体注入，并且在相反的情况下，宣告警报并停止液体注射。 因此，液体注射器容易且可靠地防止诸如造影剂的液体不适当地向患有肾功能障碍的患者注射。

公开(公告)号：US20100174191A1

公开(公告)日：2010-07-08

申请号：US12632156

申请日：2009-12-07

Applicant: Chin-An LIN ,  Guo-Zua Wu ,  Sun-Hua Pao ,  Chien-Hsing Huang ,  Hsing-Cheng Yu ,  Hung-Yueh Chen

Inventor： Chin-An LIN ,  Guo-Zua Wu ,  Sun-Hua Pao ,  Chien-Hsing Huang ,  Hsing-Cheng Yu ,  Hung-Yueh Chen

IPC: A61B8/14 ,  A61B5/0402

CPC classification number: A61B8/13 ,  A61B5/02007 ,  A61B5/201 ,  A61B8/145 ,  A61B8/4254 ,  A61B8/483 ,  A61B8/543

Abstract: A system and method thereof for capturing and reconstructing a dynamic 3D ultrasound image of a blood vessel are provided. The present system includes a ultrasound transducer, a motor positioning system, an electrocardiograph, a microprocessor for processing ultrasound images and signals capturing by the ultrasound transducer, and a monitor displaying the dynamic 3D ultrasound image. The motor positioning system controls the ultrasound transducer to capture 2D ultrasound images of the blood vessel at several locations in a predetermined urea. During the capturing process, capturing times, electrocardiograms and 3D locations of those captured 2D ultrasound images are simultaneously recoded. Finally, those captured 2D ultrasound images are reconstructed to the dynamic 3D ultrasound image of the blood vessel according to the time bases based on the phases of the electrocardiograms.

Abstract translation: 提供了一种用于捕获和重建血管的动态3D超声波图像的系统及其方法。 本系统包括超声波换能器，马达定位系统，心电图仪，用于处理超声波图像的微处理器和由超声波换能器捕获的信号，以及显示动态3D超声波图像的监视器。 电动机定位系统控制超声换能器以在预定的尿素中的几个位置处捕获血管的2D超声图像。 在拍摄过程中，拍摄的2D超声图像的拍摄时间，心电图和3D位置被同时重新编码。 最后，根据心电图的相位，将所拍摄的2D超声图像根据时基重建为血管的动态3D超声图像。

公开(公告)号：US20100152608A1

公开(公告)日：2010-06-17

申请号：US12537403

申请日：2009-08-07

Applicant: John D. HATLESTAD ,  Binh C. TRAN ,  Bin MI ,  Ronald W. HEIL, JR.

Inventor： John D. HATLESTAD ,  Binh C. TRAN ,  Bin MI ,  Ronald W. HEIL, JR.

IPC: A61B5/00 ,  A61B5/11

CPC classification number: A61B5/0205 ,  A61B5/0028 ,  A61B5/0031 ,  A61B5/03 ,  A61B5/036 ,  A61B5/201 ,  A61B5/416 ,  A61B5/6846

Abstract: An implantable system for ambulatory monitoring of a high-risk heart failure patient includes a first pressure sensor implantable within an abdomen of the patient for sensing and generating an output representative of a baseline intra-abdominal pressure value of the patient and for chronically sensing and generating an output representative of an intra-abdominal pressure value of the patient at periodic intervals. At least one second implantable sensor is provided for sensing and generating an output representative of a second physiological parameter of the patient. Additionally, the system includes a processor for correlating the output of the first pressure sensor and the second physiologic sensor, and for comparing differences between the baseline intra-abdominal pressure value and subsequent intra-abdominal pressure values. The processor can reside in another implantable device or in an external device/system.

Abstract translation: 用于高风险心力衰竭患者的动态监测的可植入系统包括可植入患者腹部的第一压力传感器，用于感测和产生代表患者的基线腹内压力值的输出，并且用于长期感测和产生 以周期性间隔代表患者的腹内压力值的输出。 提供至少一个第二可植入传感器用于感测和产生代表患者的第二生理参数的输出。 另外，该系统包括用于将第一压力传感器和第二生理传感器的输出相关联并且用于比较基线腹内压力值和随后的腹内压力值之间的差异的处理器。 处理器可以驻留在另一个可植入设备中或外部设备/系统中。

公开(公告)号：US20100121220A1

公开(公告)日：2010-05-13

申请号：US12527977

申请日：2008-02-18

Applicant: Vasu Nishtala

Inventor： Vasu Nishtala

IPC: A61B5/20

CPC classification number: A61B5/201 ,  A61B5/0084 ,  A61B5/14507 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/208 ,  A61B5/412 ,  A61B2562/0238 ,  G01N33/70 ,  G01N2800/347

Abstract: A continuous Glomerular Filtration Rate (GFR) estimation system may include a Foley catheter, a continuous urine creatinine sensor, and a urine output monitor. The continuous GFR estimation system computes creatinine clearance as CrCl=(Ucr×Uvol)/(Pcr×Imim), where Ucr is urine creatinine in mg/dL, Uvol is urine volume in mL, Pcr is plasma (serum) creatinine in mL, and Imin is time in minutes. A Foley catheter may be used to withdraw urine from the bladder. The urine may be delivered to a urine output monitor that provides the Uvol value over a time Imin. Attached to the catheter is the flow-through continuous urine creatinine sensor for providing the Ucr value. The remaining parameter is Pcr. Because serum creatinine levels do not change rapidly over time, a blood sample may be withdrawn prior to the start of the continuous GFR to obtain the PCr value.

Abstract translation: 连续的肾小球滤过率（GFR）估计系统可以包括Foley导管，连续尿肌酐传感器和尿液输出监测器。 连续GFR估计系统计算肌酐清除率为CrCl =（Ucr×Uvol）/（Pcr×Imim），其中Ucr为尿肌酐，单位为mg / dL，Uvol为尿量，mL，Pcr为血浆（血清）肌酐，单位为mL， 而Imin是几分钟的时间。 Foley导管可用于从膀胱抽出尿液。 尿液可以输送到尿液输出监测器，在一段时间内提供Uvol值。 连接到导管是用于提供Ucr值的流通连续尿肌酐传感器。 剩余的参数是Pcr。 由于血清肌酐水平随着时间的推移不会迅速变化，因此可以在连续GFR开始之前撤回血液样本以获得PCr值。

公开(公告)号：US20090306625A1

公开(公告)日：2009-12-10

申请号：US12404137

申请日：2009-03-13

Applicant: Nikhil L. Pereira-Kamath ,  Harry B. Goodson, IV ,  Jeffrey M. Elkins ,  Samir R. Patel

Inventor： Nikhil L. Pereira-Kamath ,  Harry B. Goodson, IV ,  Jeffrey M. Elkins ,  Samir R. Patel

IPC: A61M25/01

CPC classification number: A61K31/436 ,  A61B5/201 ,  A61B5/412 ,  A61K35/28 ,  A61K35/545 ,  A61K38/18 ,  A61K38/2013 ,  A61K38/212 ,  A61M25/0067 ,  A61M25/0071 ,  A61M2025/1045 ,  A61M2210/1082

Abstract: Systems and methods are provided for locally delivering specific prophylactic, regenerative, or therapeutic agents within the body of a patient. Systems and methods can involve direct delivery of prophylactic, regenerative, or therapeutic agents into branch blood vessels or body lumens from a main vessel or lumen, respectively, and in particular into renal arteries extending from an aorta in a patient. Drug infusion techniques encompass specific treatment and prevention regimes for renal diseases including, but not limited to, Acute Kidney Injury, Renal Cell Carcinoma, Polycystic Kidney Disease, and Chronic Kidney Disease.

Abstract translation: 提供的系统和方法用于在患者体内局部递送特定的预防，再生或治疗剂。 系统和方法可以包括将预防性，再生的或治疗剂分别直接递送到分支血管或来自主血管或内腔的体腔，特别是从病人主动脉延伸的肾动脉。 药物输注技术包括肾脏疾病的具体治疗和预防方案，包括但不限于急性肾损伤，肾细胞癌，多囊肾病和慢性肾脏疾病。

公开(公告)号：US20080221551A1

公开(公告)日：2008-09-11

申请号：US12044373

申请日：2008-03-07

Applicant: Harry B. Goodson ,  Jeffrey M. Elkins ,  Samir R. Patel

Inventor： Harry B. Goodson ,  Jeffrey M. Elkins ,  Samir R. Patel

IPC: A61M31/00 ,  A61M25/00

CPC classification number: A61M25/0068 ,  A61B5/201 ,  A61B5/412 ,  A61M25/0071

Abstract: Systems and methods for the clinical treatment of individuals susceptible to or suffering from acute kidney injury are provided. Drugs, biologics, or other therapies or treatments are administered by fluid agent delivery directly to the kidneys via their arterial blood supply. Bifurcated renal artery infusion catheter devices and methods can treat kidney injury in patients with locally-delivered drugs, biologics, and other agents, so as to increase the ability of the kidneys to excrete nitrogenous waste products from the blood, and prevent or ameliorate azotemia.

Abstract translation: 提供了对急性肾损伤或患有急性肾损伤的个体进行临床治疗的系统和方法。 药物，生物制剂或其他疗法或治疗通过流体剂通过其动脉血供给直接递送至肾来施用。 分叉肾动脉输液导管装置和方法可以治疗局部输送药物，生物制剂等药物的肾损伤，以增加肾脏从血液中排出含氮废物的能力，并预防或改善氮血症。

公开(公告)号：US20080154106A1

公开(公告)日：2008-06-26

申请号：US11999634

申请日：2007-12-06

Applicant: Mihailo V. Rebec

Inventor： Mihailo V. Rebec

IPC: A61B5/1473

CPC classification number: A61B5/201 ,  A61B5/0002 ,  A61B5/145 ,  A61B5/14528 ,  A61B5/14546 ,  A61B5/686 ,  A61B2010/008

Abstract: A method of using a diffusion-based, continuous-monitoring system to analyze for a disease or condition includes creating a diffusion channel in an area of skin. The diffusion channel is maintained for a desired duration. The level of the disease marker(s) is continuously monitored for the desired duration via a diffusion-based, continuous-monitoring device. The levels of the at least one disease marker at the area of skin are analyzed to determine if the disease or condition associated with the at least one disease marker is present.

Abstract translation: 使用基于扩散的连续监测系统来分析疾病或病症的方法包括在皮肤区域中产生扩散通道。 扩散通道保持期望的持续时间。 疾病标志物的水平通过基于扩散的连续监测装置连续监测所需的持续时间。 分析皮肤区域上的至少一种疾病标记物的水平，以确定与至少一种疾病标记物相关的疾病或病症是否存在。

公开(公告)号：US20060264741A1

公开(公告)日：2006-11-23

申请号：US11493055

申请日：2006-07-26

Applicant: Martin Prince

Inventor： Martin Prince

IPC: A61B5/05

CPC classification number: A61K49/18 ,  A61B5/02007 ,  A61B5/055 ,  A61B5/201 ,  A61B5/416 ,  A61B5/7285 ,  G01R33/281 ,  G01R33/5619 ,  G01R33/563 ,  G01R33/56308

Abstract: The present invention is a technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation. This technique and apparatus allows for imaging the aorta at a fraction of the cost of conventional aortography and without the risks of arterial catheterization or iodinated contrast.

公开(公告)号：US20060074294A1

公开(公告)日：2006-04-06

申请号：US10959466

申请日：2004-10-06

Applicant: Robert Williams ,  Brad Schreck ,  Jeff Cushner

Inventor： Robert Williams ,  Brad Schreck ,  Jeff Cushner

IPC: A61B5/05

CPC classification number: A61B5/201 ,  A61B5/0046 ,  A61B5/055 ,  A61B5/14546 ,  A61B6/481 ,  A61B6/504 ,  A61B8/481

Abstract: A medical imaging system, dispensing system, method, and computer program product for analyzing biological fluid chemistry as part of a medical imaging procedure are provided. The system of the present invention provides a biological fluid analyzer configured to analyze a biological fluid sample for the presence of specific components that indicate patient's ability to safely process and clear injected contrast media from the vasculature that may be injected as part of the medical imaging procedure. The medical imaging system, dispensing system, and method for analyzing biological fluid chemistry are further provided as part of the medical imaging procedure and/or medical imaging suite so as to be capable of determining in real time, a patient's ability to safely clear injected contrast media.

Abstract translation: 提供了用于分析生物流体化学作为医学成像过程的一部分的医学成像系统，分配系统，方法和计算机程序产品。 本发明的系统提供了一种生物流体分析器，其被配置为分析生物流体样品以存在特定组分，其指示患者能够安全地处理和清除来自可作为医学成像程序的一部分注射的脉管系统的注射造影剂 。 进一步提供用于分析生物流体化学的医学成像系统，分配系统和方法作为医学成像过程和/或医学成像套件的一部分，以便能够实时确定患者安全地清除注射的对比度的能力 媒体。

公开(公告)号：US06847841B1

公开(公告)日：2005-01-25

申请号：US09721610

申请日：2000-11-24

Applicant: Mohamed Khaled-Mohamed El Hatw

Inventor： Mohamed Khaled-Mohamed El Hatw

IPC: A61B5/04 ,  A61B5/05 ,  A61B5/20 ,  A61B10/00 ,  A61B10/02 ,  A61B17/00

CPC classification number: A61B10/0233 ,  A61B5/04 ,  A61B5/05 ,  A61B5/0538 ,  A61B5/20 ,  A61B5/201 ,  A61B5/4519 ,  A61B2017/00026

Abstract: A diagnostic cylindrical probe introduced through the body surfaces to the target tissue to detect the resistance of the tissues to piercing, its electrical activity and its resistance to passage of electrical current to identify the nature of the tissue and predict the nature of its pathology during needle biopsy has a sharp piercing tip attached to its end through a coiled wire to slide over the surface of an inbuilt changeable electrical resistance incorporated in an electrical circuit to detect the mechanical resistance of the tissues to piercing, a sensor at its tip incorporated in a second electrical circuit to detect the electrical impedance of the target tissue and a secondary electrically isolated sensor incorporated with the first sensor in a third electrical circuit to detect the electrical resistance of the tissues to passage of electrical current.

Abstract translation: 将诊断性圆柱形探针通过身体表面引入目标组织以检测组织对穿刺的抵抗力，其电活动及其对电流通过的抵抗力，以确定组织的性质并预测其针状物的病理性质 活检具有通过螺旋线连接到其端部的尖锐刺穿尖端，以在结合在电路中的内置可变电阻的表面上滑动以检测组织穿刺的机械阻力，其末端的传感器并入第二 电路以检测目标组织的电阻抗和在第三电路中与第一传感器结合的次级电隔离传感器，以检测组织对电流通过的电阻。