公开(公告)号：US20180289980A1

公开(公告)日：2018-10-11

申请号：US15567400

申请日：2016-04-11

Applicant: RaySearch Laboratories AB

Inventor： Albin FREDRIKSSON ,  Erik ENGWALL

IPC: A61N5/10

Abstract: An optimization method for a radiotherapy plan using robust optimization to handle different scenarios that may occur during one treatment session because of patient movement. The optimization is based on the period and amplitude of the movement, the starting point of the treatment session within a period and the delivery time structure.

公开(公告)号：US20180078783A1

公开(公告)日：2018-03-22

申请号：US15563768

申请日：2016-03-30

Applicant: RaySearch Laboratories AB

Inventor： Björn HÅRDEMARK

IPC: A61N5/10 ,  G06F19/00

Abstract: A database stores pre-calculated solutions each of which defines a radiation therapy treatment plan for a treatment volume associated with at least one target and at least one organ-at-risk. The pre-calculated solutions are divided into at least two groups each of which includes at least one pre-calculated solution. The pre-calculated solutions in a given group represent radiation therapy treatment plans which share a common beam configuration. A radiation therapy treatment plan (sc) is established based on the pre-calculated solutions as follows. A first user interface receives operator commands specifying criteria for selecting radiation therapy treatment plans from the database, the criteria defining a set of parameters for the treatment volume. In particular, the operator commands jointly specify criteria for selecting radiation therapy treatment plans from more than one of the at least two groups. When establishing a solution, a preference function is applied on at least two pre-calculated solutions to establish one and only one solution as a radiation therapy treatment plan (sc) meeting the criteria.

公开(公告)号：US09694204B2

公开(公告)日：2017-07-04

申请号：US14781415

申请日：2013-12-02

Applicant: RaySearch Laboratories AB

Inventor： Björn Hårdemark

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1038 ,  A61N5/1039 ,  A61N5/1045 ,  A61N2005/1074

Abstract: A method for generating a robust radiotherapy treatment plan for a treatment volume of a subject. An adjusted voxel-specific dose objective is determined by “smearing” an initial voxel-specific dose objective a specified distance in at least one direction. A treatment plan based on such adjusted dose objective will be more robust with respect to setup uncertainties and organ movements. Smearing of the dose objective corresponds to adjusting the dose objective dose value of a voxel in accordance with dose objective dose values of voxels within the specified distance.

公开(公告)号：US20170157423A1

公开(公告)日：2017-06-08

申请号：US15367872

申请日：2016-12-02

Applicant: RaySearch Laboratories AB

Inventor： Rasmus BOKRANTZ ,  Björn HÅRDEMARK

IPC: A61N5/10

CPC classification number: A61N5/1038 ,  A61N5/103 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1047 ,  A61N5/1071

Abstract: An output radiation treatment plan for at least one target in a treatment volume is determined. Each target is associated with a prescribed radiation dose. An updated treatment plan causes the prescribed radiation dose to be delivered to the target when implemented by a radiation therapy machine. The updated treatment plan requires an updated delivery time to complete and is calculated by: [i] receiving a numerical value designating an upper bound on modulation efficiency of the updated treatment plan, [ii] receiving a current treatment plan, [iii] calculating a current delivery time for the current treatment plan, [iv] calculating an un-modulated delivery time for the current treatment plan, and [v] calculating the updated treatment plan by executing an optimization process while satisfying the upper bound on the modulation efficiency. Steps [ii] to [v] are traversed a predetermined number of times. Thereafter, the output radiation treatment plan is generated.

公开(公告)号：US20160303398A1

公开(公告)日：2016-10-20

申请号：US15106097

申请日：2013-12-20

Applicant: RaySearch Laboratories AB

Inventor： Kjell ERIKSSON

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N2005/1035

Abstract: A method for generating a radiotherapy treatment plan for a patient is provided. The treatment plan is optimized using an optimization objective which is at least partly based on an initially planned dose to the patient.

Abstract translation: 提供了一种用于产生患者放射治疗计划的方法。 治疗计划使用优化目标进行优化，该优化目标至少部分基于对患者的初始计划剂量。

公开(公告)号：US20160144198A1

公开(公告)日：2016-05-26

申请号：US14903192

申请日：2013-12-20

Applicant: RAYSEARCH LABORATORIES AB

Inventor： Johan LÖF

IPC: A61N5/10

CPC classification number: A61N5/103 ,  G06F19/3481 ,  G16H40/20

Abstract: A method for automatic selection of a treatment plan for a patient is provided, where the automatic selection is at least partly based on the plan quality and required resources for each treatment plan in relation to the availability of resources.

Abstract translation: 提供了一种用于自动选择患者治疗计划的方法，其中自动选择至少部分地基于与资源可用性相关的每个治疗计划的计划质量和所需资源。

公开(公告)号：US20160051840A1

公开(公告)日：2016-02-25

申请号：US14781415

申请日：2013-12-02

Applicant: RAYSEARCH LABORATORIES AB

Inventor： Björn HÅRDEMARK

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1038 ,  A61N5/1039 ,  A61N5/1045 ,  A61N2005/1074

Abstract: A method for generating a robust radiotherapy treatment plan for a treatment volume of a subject. An adjusted voxel-specific dose objective is determined by “smearing” an initial voxel-specific dose objective a specified distance in at least one direction. A treatment plan based on such adjusted dose objective will be more robust with respect to setup uncertainties and organ movements. Smearing of the dose objective corresponds to adjusting the dose objective dose value of a voxel in accordance with dose objective dose values of voxels within the specified distance.

Abstract translation: 一种用于产生用于受试者的治疗体积的强壮的放射疗法治疗计划的方法。 通过在至少一个方向上“指定”初始体素特异性剂量目标指定的距离来确定经调整的体素特异性剂量目标。 基于这种调整剂量目标的治疗计划在设置不确定性和器官移动方面将更加强大。 剂量目标的拖尾对应于根据指定距离内的体素的剂量目标剂量值调整体素的剂量目标剂量值。