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    A METHOD OF ION PBS TREATMENT OPTIMIZATION, COMPUTER PROGRAM PRODUCT AND COMPUTER SYSTEM FOR PERFORMING THE METHOD
    2.
    发明公开
    A METHOD OF ION PBS TREATMENT OPTIMIZATION, COMPUTER PROGRAM PRODUCT AND COMPUTER SYSTEM FOR PERFORMING THE METHOD 审中-公开

    公开(公告)号：US20240082602A1

    公开(公告)日：2024-03-14

    申请号：US18552670

    申请日：2022-02-17

    Applicant: RaySearch Laboratories AB (Publ)

    Inventor： Lars GLIMELIUS ,  Erik ENGWALL ,  Otte MARTHIN

    IPC: A61N5/10

    CPC classification number: A61N5/1031 ,  A61N5/1043 ,  A61N2005/1087

    Abstract: A computer-based method of providing a set of selected spots for use in ion radiotherapy optimization is proposed, the method comprising the steps of defining a number of positions in the volume, each position corresponding to a possible Bragg peak location, the positions being defined to provide coverage of the volume, for each position, for at least one beam direction, performing a ray trace to determine characteristics of a potential spot in the beam that will place its Bragg peak in the position and for each position, selecting zero, one or more of the potential spots, based on the characteristics, and including the one or more selected spots in the set of selected spots. The set of selected spots may be used in treatment planning. The invention also relates to computer program products and a computer system for performing the methods.

    RADIOTHERAPY TREATMENT PLAN EVALUATION AND IMPROVEMENT
    4.
    发明申请
    RADIOTHERAPY TREATMENT PLAN EVALUATION AND IMPROVEMENT 有权

    公开(公告)号：US20250121208A1

    公开(公告)日：2025-04-17

    申请号：US18681084

    申请日：2022-06-16

    Applicant: RaySearch Laboratories AB

    Inventor： Erik TRANEUS ,  Lars GLIMELIUS ,  Erik ENGWALL ,  Elias CONIAVITIS

    IPC: A61N5/10 ,  G16H20/40

    Abstract: A radiotherapy treatment plan may be evaluated based on a combination of two or more metrics, by the steps of simulating the result of delivery of the plan, obtaining values from the simulation for at least a first and a second metric, performing a multivariate analysis of the values and determining a quality of the plan based on the result of the multivariate analysis. The metrics may include at least one of dose, LET, track ends, RBE, alpha/beta ratio and statistical uncertainty of the plan.

    A METHOD AND A CORRESPONDING RADIATION TREATMENT SYSTEM FOR FACILITATING OPTIMIZATION OF A MULTIMODAL RADIATION THERAPY PLAN
    5.
    发明申请
    A METHOD AND A CORRESPONDING RADIATION TREATMENT SYSTEM FOR FACILITATING OPTIMIZATION OF A MULTIMODAL RADIATION THERAPY PLAN 有权

    公开(公告)号：US20210205635A1

    公开(公告)日：2021-07-08

    申请号：US17057170

    申请日：2019-05-27

    Applicant: RaySearch Laboratories AB

    Inventor： Rasmus BOKRANTZ ,  Albin FREDRIKSSON ,  Kjell ERIKSSON ,  Erik ENGWALL ,  Erik TRANEUS

    IPC: A61N5/10

    Abstract: The present disclosure generally relates to the field of radiation treatment. More specifically, the present disclosure generally relates to methods and radiation treatment systems for facilitating a multimodal radiation therapy treatment plan, in particular a multimodal radiation therapy plan employing a combined photon beam and electron beam radiation treatment. According to one example embodiment described in the disclosure, a method may comprise obtaining information related to a set of candidate beam types for the combined photon beam and electron beam radiation treatment; comparing the set of candidate beam types against a selection criterion to establish a subset of beam types from the candidate beam types; and generating the combined photon beam and electron beam radiation treatment plan utilizing the thus established subset of beam types.

    ASSIGNING RIPPLE FILTER SETTINGS
    6.
    发明申请
    ASSIGNING RIPPLE FILTER SETTINGS 有权

    公开(公告)号：US20210154492A1

    公开(公告)日：2021-05-27

    申请号：US16625988

    申请日：2018-06-28

    Applicant: RaySearch Laboratories AB

    Inventor： Erik ENGWALL ,  Martin JANSON ,  Lars GLIMELIUS

    IPC: A61N5/10

    Abstract: It is provided a method for determining ripple filter settings for an ion therapy beam being capable of providing ions of different energy levels to a target volume. The method is performed in a treatment planning system and comprises the steps of: determining at least one beam direction to use to cover a target volume; and assigning a ripple filter setting to each one of a plurality of sub-beams of each one of the at least one beam direction such that each sub-beam is assigned a different ripple filter setting, wherein each ripple filter setting results in a different effect on a Bragg peak width in a direction along the beam, and each energy level is assigned to one of the plurality of sub-beams. The step of assigning a ripple filter setting comprises optimizing based on different filter settings for different sub-beams for each beam direction.

    SYSTEM AND METHOD FOR PLANNING OF PASSIVE ION RADIOTHERAPY TREATMENT
    8.
    发明申请
    SYSTEM AND METHOD FOR PLANNING OF PASSIVE ION RADIOTHERAPY TREATMENT 有权

    公开(公告)号：US20220023664A1

    公开(公告)日：2022-01-27

    申请号：US17309671

    申请日：2019-12-19

    Applicant: RaySearch Laboratories AB

    Inventor： Albin FREDRIKSSON ,  Erik ENGWALL

    IPC: A61N5/10

    Abstract: An ion-based radiotherapy plan for passive delivery of one or more beams (7) uses an optimization problem set up to allow variation in settings of the range modulating device, and/or settings of the aperture element during the delivery of the first beam, so that said plan will include modulation of the fluence of the beam during the delivery of the beam. The optimization problem is set up to allow variation of the settings of an aperture element (11), a range modulating device (9) during delivery of each beam, so that said plan will include modulation in depth of the beam during the delivery of the beam.

    DETERMINING A DISTRIBUTION OF SPOTS OF VARYING SIZES FOR ION BEAM THERAPY BASED ON USER CONFIGURATION
    9.
    发明申请
    DETERMINING A DISTRIBUTION OF SPOTS OF VARYING SIZES FOR ION BEAM THERAPY BASED ON USER CONFIGURATION 审中-公开

    公开(公告)号：US20200147410A1

    公开(公告)日：2020-05-14

    申请号：US16625895

    申请日：2018-06-26

    Applicant: RaySearch Laboratories AB

    Inventor： Erik ENGWALL ,  Lars GLIMELIUS ,  Martin JANSON

    IPC: A61N5/10

    Abstract: It is provided a method for determining a distribution of spots for use with ion beam therapy for providing the spots in a target volume, wherein each spot represents a collection of ions of a specific energy level and of a specific size at a specific lateral location. The method is performed in a treatment planning system and comprises the steps of: dividing the target volume in a plurality of target sections based on a user configuration comprising at least one spot size strategy defining a maximum spot size at the location of a Bragg peak; assigning a spot size strategy to each one of the target sections based on the location of the respective target section; and determining, within each target section, spots in accordance with its spot size strategy.

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