公开(公告)号：US1917311A

公开(公告)日：1933-07-11

申请号：US48081630

申请日：1930-09-09

Applicant: SCOTTISH DYES LTD

Inventor： JENKIN LOVELUCK RHYS ,  JOHN THOMAS

IPC: C07C205/61

CPC classification number: C07C205/61 ,  C07C51/363 ,  C07C65/34 ,  C07C201/08 ,  C07C227/04 ,  C07C229/66

公开(公告)号：US1838311A

公开(公告)日：1931-12-29

申请号：US16504627

申请日：1927-01-31

Applicant: SUMNER E CAMPBELL

Inventor： IHRIG HARRY K

IPC: C07C201/08 ,  C07C205/06 ,  C07C205/57

CPC classification number: C07C201/08 ,  C07C205/06 ,  C07C205/57

公开(公告)号：US1723761A

公开(公告)日：1929-08-06

申请号：US64217523

申请日：1923-05-29

Applicant: BRADNER DONALD B ,  BEALL FRANK H

Inventor： BRADNER DONALD B ,  BEALL FRANK H

IPC: C07C205/23

CPC classification number: C07C201/08 ,  Y02P20/582 ,  C07C205/23

公开(公告)号：US1688837A

公开(公告)日：1928-10-23

申请号：US1688837D

CPC classification number: C07C205/06 ,  C07C201/08 ,  C07C2603/54

公开(公告)号：US1457543A

公开(公告)日：1923-06-05

申请号：US1457543D

IPC: C07C205/06

CPC classification number: C07C201/08 ,  C07C205/06

公开(公告)号：US11655203B2

公开(公告)日：2023-05-23

申请号：US17288819

申请日：2019-10-24

Applicant: ETH ZURICH

Inventor： Dmitry Katayev ,  Kun Zhang ,  Roxan Calvo

IPC: C07C201/08 ,  C07D275/06

CPC classification number: C07C201/08 ,  C07D275/06 ,  C07C201/08 ,  C07C205/06 ,  C07C201/08 ,  C07C205/11 ,  C07C201/08 ,  C07C205/37 ,  C07C319/20 ,  C07C323/09 ,  C07C209/02 ,  C07C211/45 ,  C07C201/08 ,  C07C205/57 ,  C07C253/30 ,  C07C255/50 ,  C07C201/08 ,  C07C205/44 ,  C07C201/08 ,  C07C205/45 ,  C07C315/04 ,  C07C317/14 ,  C07C201/08 ,  C07C205/56 ,  C07C231/12 ,  C07C237/04 ,  C07C201/08 ,  C07C205/38

Abstract: A process for preparing a nitrated compound, including the step of reacting a compound (A) including at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein the heteroaromatic ring includes at least one heteroatom selected from the group consisting of oxygen, sulfur, phosphor, selenium and nitrogen, with a compound of formula (I)




wherein Y is selected from the group consisting of hydrogen and nitro.

公开(公告)号：US20190071393A1

公开(公告)日：2019-03-07

申请号：US16084979

申请日：2017-03-23

Applicant: SHENYANG PHARMACEUTICAL UNIVERSITY

Inventor： Guoliang CHEN ,  Zhonghui ZHENG ,  Libo ZOU ,  Daiming ZHANG ,  Chunling YUAN ,  Fulong REN ,  Xuefei BAO ,  Jinheng GAO ,  Linbo ZHOU ,  Wuhong FANG

IPC: C07C275/38 ,  C07C2/86 ,  C07C201/08 ,  C07C209/36 ,  C07C231/02 ,  C07C273/18 ,  C07D295/195 ,  C07C271/28 ,  C07C269/04 ,  C07C311/48 ,  C07C303/38 ,  C07D211/62

CPC classification number: C07C275/38 ,  A61K31/167 ,  C07C2/861 ,  C07C201/08 ,  C07C209/36 ,  C07C231/02 ,  C07C231/12 ,  C07C233/65 ,  C07C233/80 ,  C07C259/10 ,  C07C269/04 ,  C07C269/06 ,  C07C271/28 ,  C07C271/60 ,  C07C273/1809 ,  C07C275/42 ,  C07C303/38 ,  C07C311/48 ,  C07C2603/22 ,  C07C2603/24 ,  C07D211/62 ,  C07D295/195 ,  C07C13/58 ,  C07C205/11 ,  C07C211/45 ,  C07C233/66

Abstract: An octahydroanthracene compound having the structure shown in formula (I) and (II), preparation method and application thereof are disclosed. The octahydroanthracene compound has a good therapeutic effect on tumors and neurodegenerative diseases. The preparation of the octahydroanthracene compound is mainly carried out by using benzene as a starting material, and being subjected to Friedel-Crafts reaction, nitration, reduction, (sulfo-) amide formation, reduction, urea formation or amide formation, thus obtaining a target compound.

公开(公告)号：US20180346405A1

公开(公告)日：2018-12-06

申请号：US16009396

申请日：2018-06-15

Applicant: Covestro Deutschland AG

Inventor： Thomas Knauf ,  Peter Drinda

IPC: C07C201/08 ,  B01J19/24 ,  B01J19/18 ,  B01J19/00 ,  C07C201/16 ,  C07C205/06

CPC classification number: C07C201/08 ,  B01J19/0006 ,  B01J19/002 ,  B01J19/1881 ,  B01J19/24 ,  B01J19/2465 ,  B01J2219/00006 ,  B01J2219/0004 ,  B01J2219/00268 ,  C07C201/16 ,  C07C205/06

Abstract: The present invention relates to a process for the continuous production of nitrobenzene by the nitration of benzene with nitric acid and sulphuric acid under adiabatic conditions, not the entire production plant being shut down during a production stop, but the production plant being entirely or at least partly operated in recirculation mode. The invention further relates to a plant for producing nitrobenzene and to a method for operating a plant for producing nitrobenzene.

公开(公告)号：US09771291B2

公开(公告)日：2017-09-26

申请号：US14784699

申请日：2014-04-14

Applicant: COVESTRO DEUTSCHLAND AG

Inventor： Thomas Knauf ,  Antoni Mairata ,  Erik Sluyts ,  Jan Van Tricht

IPC: C02F9/00 ,  C02F1/02 ,  C02F1/20 ,  C07C201/08 ,  C07C201/16 ,  C07C209/36 ,  C02F1/04 ,  C02F101/32 ,  C02F101/38 ,  C02F103/18

CPC classification number: C02F9/00 ,  C02F1/025 ,  C02F1/04 ,  C02F1/20 ,  C02F2101/322 ,  C02F2101/38 ,  C02F2103/18 ,  C02F2209/06 ,  C02F2301/046 ,  C07C201/08 ,  C07C201/16 ,  C07C209/36 ,  C07C205/06

Abstract: The invention relates to a process for working up alkaline waste water which is formed during washing of crude nitrobenzene obtained by nitration of benzene, wherein (i) the alkaline waste water is heated under an increased pressure with respect to atmospheric pressure with exclusion of oxygen and is then cooled and expanded; (ii) the waste water obtained in (i) is purified further by stripping with a stripping gas and the stripping gas stream loaded with impurities is then cooled to a temperature of from 10° C. to 60° C.; and (iii) the liquid process product obtained in (ii) by cooling the stripping gas stream loaded with impurities is separated into an aqueous and an organic phase and the organic phase is used further in an aniline production process.

公开(公告)号：US20170218347A1

公开(公告)日：2017-08-03

申请号：US15515303

申请日：2015-10-07

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Denis GRIBKOV

IPC: C12N9/10 ,  C12P19/44

CPC classification number: C12N9/1085 ,  C07C45/63 ,  C07C201/08 ,  C12P19/44 ,  C07C205/45 ,  C07C49/80

Abstract: The invention relates to a process for the preparation of a compound of formula I (I), wherein R1 is hydrogen, fluoro or chloro; which process comprises a) reacting a compound of formula II (II), wherein R1 is hydrogen, fluoro or chloro; with a nitration agent to the compound of formula (III), wherein R1 is hydrogen, fluoro or chloro; and b) reacting the compound of formula III with chlorine gas at temperature from 180° C. to 250° C. to the compound of formula I.