公开(公告)号：US11759119B2

公开(公告)日：2023-09-19

申请号：US17664523

申请日：2022-05-23

Applicant: GYRUS ACMI, INC.

Inventor： Tailin Fan

IPC: A61B5/00 ,  A61B5/05 ,  A61B17/34 ,  A61B5/06 ,  G01R33/00 ,  G01R33/09 ,  A61B34/20 ,  A61B5/20 ,  A61B90/00

CPC classification number: A61B5/05 ,  A61B5/062 ,  A61B5/6848 ,  A61B17/3403 ,  G01R33/0017 ,  G01R33/0029 ,  G01R33/09 ,  A61B5/201 ,  A61B2034/2051 ,  A61B2090/3954 ,  A61B2560/0223 ,  A61B2562/04

Abstract: A surgical locator circuit identifies a surgical target such as a kidney stone by disposing an emitter such as a magnetic source behind or adjacent the surgical target, and employing the circuit to identify an axis to the emitter, thus defining an axis or path to the surgical target. An array of sensors arranged in an equidistant, coplanar arrangement each senses a signal indicative of a distance to the emitter. A magneto resistor sensor generates a variable resistance is responsive to the distance to a magnetic coil emitting a magnetic field. An equal signal from each of the coplanar sensors indicates positioning on an axis passing through a point central to the sensors and orthogonal to the plane. A fixed element and signal conditioner augments and normalizes the signal received from each of the sensors to accommodate subtle differences in magneto resistive response among the plurality of sensors.

公开(公告)号：US11744498B2

公开(公告)日：2023-09-05

申请号：US16932212

申请日：2020-07-17

Applicant: Covidien LP

Inventor： David J. Miller

IPC: A61B5/20 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/00 ,  A61M25/04 ,  A61M25/00

CPC classification number: A61B5/201 ,  A61B5/1459 ,  A61B5/14546 ,  A61B5/208 ,  A61B5/6852 ,  A61B5/7275 ,  A61M25/04 ,  A61M25/0017 ,  A61M2205/3576 ,  A61M2205/52

Abstract: In one example, the disclosure relates to a catheter system comprising an elongated body defining a lumen. The elongated body comprising a proximal portion and a distal portion. An anchoring member is positioned on the proximal portion of the elongated body. The anchoring member configured to anchor the proximal portion of the elongated body to a patient. The catheter system includes one or more sensors positioned on the elongated body. The one or more sensors are configured to sense a parameter of a fluid within the lumen of the elongated body. The catheter system includes memory positioned on the elongated body, the memory configured to store patient-specific information.

公开(公告)号：US11672456B2

公开(公告)日：2023-06-13

申请号：US16394438

申请日：2019-04-25

Applicant: Medtronic Ireland Manufacturing Unlimited Company

Inventor： Abhijeet Dubhashi

IPC: A61B5/20 ,  A61B5/021 ,  G06N3/08 ,  G16H10/60 ,  G16H50/30 ,  A61B5/00 ,  A61B5/02

CPC classification number: A61B5/201 ,  A61B5/02108 ,  A61B5/6824 ,  A61B5/7267 ,  G06N3/08 ,  A61B5/02007 ,  G16H10/60 ,  G16H50/30

Abstract: Example devices, systems, and techniques predict renal denervation efficacy for reducing hypertension in a patient based on pulse information. For example, a system may include processing circuitry configured to obtain pulse information representative of pulses from both wrists of a patient, obtain a plurality of values representative of respective patient metrics for the patient, and apply the pulse information and the plurality of values to a deep learning model trained to represent a relationship of the pulse information and the patient metrics to an efficacy of renal denervation in reducing hypertension. In some examples, responsive to applying the pulse information and the plurality of values to the deep learning model, the processing circuitry obtains, from the deep learning model, a score indicative of renal denervation efficacy in reducing hypertension for the patient, and generates a graphical user interface comprising a graphical representation of the score for the patient.

公开(公告)号：US11669970B2

公开(公告)日：2023-06-06

申请号：US16500875

申请日：2018-04-09

Applicant: Children's National Medical Center

Inventor： Marius George Linguraru ,  Emily S. Blum ,  Antonio Reyes Porras Perez ,  Hans G. Pohl

IPC: G06T7/00 ,  G16H30/40 ,  A61B6/00 ,  G06F18/214 ,  G06F18/241 ,  G06F18/21 ,  G06F18/2411 ,  A61B5/20 ,  G06V10/764

CPC classification number: G06T7/0016 ,  A61B6/4057 ,  A61B6/50 ,  A61B6/5217 ,  G06F18/214 ,  G06F18/2193 ,  G06F18/241 ,  G06F18/2411 ,  G06V10/764 ,  G16H30/40 ,  A61B5/201 ,  A61B6/5247 ,  A61B2503/045 ,  G06T2207/20056 ,  G06T2207/20064 ,  G06T2207/30084

Abstract: Systems, apparatuses, and methods for diagnosing ureteropelvic junction obstruction. A set of biomarkers may be extracted from each of one or more time-activity curves associated with diuresis renography and/or functional magnetic resonance urography of one or more kidneys of a patient. One or more calculations can be performed based on the set of biomarkers to identify uretero-pelvic junction obstruction and a classification of severity or criticality thereof.

公开(公告)号：US11660032B2

公开(公告)日：2023-05-30

申请号：US16811295

申请日：2020-03-06

Applicant: SWSA Medical Ventures, LLC ,  University of Utah Research Foundation

Inventor： Natalie A. Silverton ,  Kai Kuck ,  Bradley J. Stringer ,  Spencer B. Shumway ,  Lars Lofgren

IPC: A61B5/20 ,  A61M25/10 ,  A61B5/1455 ,  A61B5/145 ,  A61B5/026

CPC classification number: A61B5/208 ,  A61B5/0261 ,  A61B5/14507 ,  A61B5/14552 ,  A61B5/14556 ,  A61B5/201 ,  A61M25/10 ,  A61B2560/0252 ,  A61M2205/0205

Abstract: An oxygen-sensing assembly for attachment to a urinary catheter may include a housing having a flow pathway extending between an inlet end and an outlet end thereof, an oxygen sensor in operable communication with the flow pathway of the housing, the oxygen sensor configured to detect oxygen levels of a fluid flowing through the flow pathway and a flowrate sensor configured to detect a flowrate of the fluid flowing through the flow pathway. A risk of acute kidney injury may be determined based on the mass flowrate of oxygen through the flow pathway, determined based on the detected oxygen levels and the flowrate of the fluid through the flow pathway. Related catheter assemblies and methods are also disclosed.

公开(公告)号：US20230158175A1

公开(公告)日：2023-05-25

申请号：US18159253

申请日：2023-01-25

Applicant: MediBeacon Inc.

Inventor： Raghavan Rajagopalan ,  Richard B. Dorshow ,  William L. Neumann ,  Thomas E. Rogers ,  Martin P. Debreczeny

IPC: A61K49/00 ,  A61M5/00 ,  A61B5/00 ,  A61B5/20 ,  C09B57/00 ,  A61P13/12 ,  C09K11/06

CPC classification number: A61K49/0021 ,  A61M5/007 ,  A61B5/0071 ,  A61B5/201 ,  A61K49/0054 ,  A61K49/0004 ,  C09B57/00 ,  A61P13/12 ,  C09K11/06 ,  C07D241/26

Abstract: A method for determining a glomerular filtration rate (GFR) in a patient includes administering to said patient a compound of Formula I and transdermally measuring spectral energy emitted by the compound of Formula I over a measurement time window. The spectral energy is emitted by the compound of Formula I in response to electromagnetic radiation delivered to the compound of Formula I. The method also includes determining the GFR in said patient based on the measured spectral energy emitted by the compound of Formula I over the measurement time window by fitting an exponential function to the spectral energy as a function of time or a linear function to the log of the spectral energy as a function of time to calculate a rate constant associated with renal clearance over the measurement time window and directly related to the GFR normalized to a body size metric of the patient.

公开(公告)号：US20230148970A1

公开(公告)日：2023-05-18

申请号：US18097348

申请日：2023-01-16

Applicant: Cardiac Pacemakers, Inc.

Inventor： Qi An ,  Pramodsingh Hirasingh Thakur ,  Viktoria A. Averina ,  Julie A. Thompson

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/02 ,  G16H50/30 ,  G16H40/63 ,  A61B5/08 ,  A61B5/20

CPC classification number: A61B5/7275 ,  A61B5/0205 ,  A61B5/02028 ,  G16H50/30 ,  G16H40/63 ,  A61B5/02 ,  A61B5/08 ,  A61B5/201 ,  A61B5/746 ,  A61B2505/07 ,  A61B5/0022 ,  G16H20/10

Abstract: Systems and methods for monitoring patients with multiple chronic diseases are described. A system may include a health status monitor that receives diagnostic data including physiological signals sensed from a patient. The system may produce at least a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease. The system may detect the first and second diseases from the physiological signals, and generate a composite health status indicator using the detections of the first and second diseases and the first and second risk indications. An alert of worsening health status may be generated if the composite detection score exceeds an alert threshold.

公开(公告)号：US20190237186A1

公开(公告)日：2019-08-01

申请号：US16282753

申请日：2019-02-22

Applicant: University of Louisville Research Foundation, Inc.

Inventor： Ayman S. El-Baz ,  Amy Dwyer ,  Ahmed Soliman ,  Mohamed Shehata ,  Hisham Abdeltawab ,  Fahmi Khalifa

IPC: G16H30/40 ,  G06T7/143 ,  G06T7/12 ,  G06T7/33 ,  G06T7/00 ,  A61B5/20 ,  G16H30/20 ,  G16H50/20

CPC classification number: G16H30/40 ,  A61B5/201 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/143 ,  G06T7/33 ,  G06T2207/10088 ,  G06T2207/10096 ,  G06T2207/20081 ,  G06T2207/30084 ,  G16H30/20 ,  G16H50/20

Abstract: A computer aided diagnostic system and automated method to classify a kidney utilizes medical image data and clinical biomarkers in evaluation of kidney function pre- and post-transplantation. The system receives image data from a medical scan that includes image data of a kidney, then segments kidney image data from other image data of the medical scan. The kidney is then classified by analyzing at least one feature determined from the kidney image data and the at least one clinical biomarker.

公开(公告)号：US20190183429A1

公开(公告)日：2019-06-20

申请号：US16104131

申请日：2018-08-16

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Kyung Hyun Sung ,  William Hsu ,  Shiwen Shen ,  Xinran Zhong

IPC: A61B5/00 ,  A61B5/055 ,  G06K9/42 ,  G06K9/52 ,  G06K9/62 ,  G06K9/66

CPC classification number: A61B5/7267 ,  A61B5/055 ,  A61B5/08 ,  A61B5/201 ,  A61B5/4244 ,  A61B5/4381 ,  G06K9/42 ,  G06K9/527 ,  G06K9/6269 ,  G06K9/66

Abstract: An automatic classification method for distinguishing between indolent and clinically significant carcinoma using multiparametric MRI (mp-MRI) imaging is provided. By utilizing a convolutional neural network (CNN), which automatically extracts deep features, the hierarchical classification framework avoids deficiencies in current schemes in the art such as the need to provide handcrafted features predefined by a domain expert and the precise delineation of lesion boundaries by a human or computerized algorithm. This hierarchical classification framework is trained using previously acquired mp-MRI data with known cancer classification characteristics and the framework is applied to mp-MRI images of new patients to provide identification and computerized cancer classification results of a suspicious lesion.

公开(公告)号：US20190008448A1

公开(公告)日：2019-01-10

申请号：US15754141

申请日：2017-10-16

Applicant: Eccrine Systems, Inc.

Inventor： Gavi Begtrup ,  Austin Morgan ,  Mikel Larson ,  Jacob A. Bertrand ,  Nicholas Bailey ,  Cory Newland ,  Robert Beech ,  Brian Hanley

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1477 ,  A61B5/0205 ,  A61B5/20 ,  G01N33/487

CPC classification number: A61B5/486 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/02438 ,  A61B5/0533 ,  A61B5/0537 ,  A61B5/1118 ,  A61B5/14517 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/201 ,  A61B5/4266 ,  A61B5/4872 ,  A61B5/4875 ,  A61B5/6801 ,  A61B5/6833 ,  A61B5/7405 ,  A61B5/7435 ,  A61B5/7455 ,  A61B5/7475 ,  A61B2560/0242 ,  G01N33/48707 ,  G01N33/48792

Abstract: Embodiments of the disclosed invention provide devices and methods to incorporate suspension-based, i.e., hydrogel-based and thixotropic compound-based, ion-selective electrodes and reference electrodes into a wearable sweat sensing device. Embodiments of this device are configured to monitor sweat electrolyte concentrations, trends, and ratios under demanding use conditions. The accompanying method includes use of the disclosed device to track fluid and electrolyte gain and loss in order to produce an electrolyte estimate, such as a sweat electrolyte concentration, a sweat electrolyte concentration trend, a sweat rate, or a concentration ratio between a plurality of electrolytes.