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公开(公告)号：US10895533B1
公开(公告)日：2021-01-19
申请号：US16820309
申请日：2020-03-16
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Röhit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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公开(公告)号：US20200370962A1
公开(公告)日：2020-11-26
申请号：US16879777
申请日：2020-05-21
Applicant: PROTRUSTECH CO., LTD
Inventor： Chun-Ta Huang , Wei-Hsin Wang , Chien-Chung Chang
Abstract: A spectrum measurement system includes a laser light source system, an optical signal receiving system and a beam splitting system. The laser light source system is configured to emit a laser output light beam to the object. The laser output light beam includes at least one of a first and a second peak-wavelength laser. After the object is radiated by the laser output light beam, the object generates a conversion beam. The conversion beam includes at least one of a first and a second spectral signals. The optical signal receiving system includes at least a first and a second signal receivers being respectively configured to receive the first and the second spectral signals. The beam splitting system provides a plurality of light exiting paths being configured to respectively transmit the first and the second spectral signals to the first and the second signal receivers.
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公开(公告)号：US10830643B2
公开(公告)日：2020-11-10
申请号：US16592135
申请日：2019-10-03
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Francesco Aieta , Charles M. Santori , Anita Rogacs
IPC: G01J3/30 , G01N21/64 , G01N15/14 , G01J3/02 , G01J3/44 , G02B21/16 , G01J3/28 , G02B21/00 , G01N15/00 , G01N21/65 , G01N15/10
Abstract: In one implementation, a spectral microscope may comprise a substrate with a planar lens, the planar lens including a phase profile including an axial focus and an oblique focus, a light source to excite a signal of a particle among a plurality of particles, and a detector to receive light generated from the light source from the axial focus of the planar lens and a spectral color component of the excited signal of the particle from the oblique focus of the planar lens.
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公开(公告)号：US20200348179A1
公开(公告)日：2020-11-05
申请号：US16728841
申请日：2019-12-27
Inventor： Keith Carron , Shane Buller , Mark Watson
IPC: G01J3/44 , G01N33/536 , G01N21/65 , G01N33/543 , G01J3/06
Abstract: A spectroscopic assay is provided. The assay comprises: a motive particle configured to move within a solution, the motive particle comprising a first analyte binding reagent for selectively binding to a target analyte; and a spectroscopic reporter particle configured to provide a predetermined spectroscopic signal in response to being interrogated by a spectrometer, the spectroscopic reporter particle comprising a second analyte binding reagent for selectively binding to the target analyte, wherein the motive particle and the spectroscopic reporter particle are configured to provide a sandwich assay in the presence of the target analyte via the first and second analyte binding reagents.
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公开(公告)号：US20200326236A1
公开(公告)日：2020-10-15
申请号：US16438127
申请日：2019-06-11
Applicant: Nanjing Nuoyuan Medical Devices Co., Ltd.
Inventor： Huiming Cai , Yiqing Wang
Abstract: The present disclosure provides a handheld laser fluorescence spectrum probe assembly, which relates to the technical field of fluorescence spectrum detection, and is designed for solving the problem of low detection precision with fluorescence spectrum detection. The handheld laser fluorescence spectrum probe assembly includes a handheld pen-like tube, an optical fiber, and a tube sleeve, wherein a first end of the tube sleeve is detachably connected with a first end of the handheld pen-like tube; a first end of the optical fiber is inserted in the handheld pen-like tube from a second end of the handheld pen-like tube, the first end of the optical fiber is connected with a dodging lens, and a distance between an end face of an end of the dodging lens away from the optical fiber and an end face of a second end of the tube sleeve is 22-28 mm.
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Patent Agency Ranking
公开(公告)号：US10803558B2
公开(公告)日：2020-10-13
申请号：US16348102
申请日：2017-11-07
Applicant: University of Southern California
Inventor： Francesco Cutrale , Scott E. Fraser
IPC: G06K9/00 , G06T5/00 , G01J3/28 , G01J3/44 , G01N21/64 , G02B21/08 , G02B21/16 , G02B21/36 , G06T5/10 , H04N5/33 , H04N9/68 , G01J3/00 , A61B5/00 , G02B21/00
Abstract: This invention relates to a hyperspectral imaging system for denoising and/or color unmixing multiple overlapping spectra in a low signal-to-noise regime with a fast analysis time. This system may be configured to carry out Hyper-Spectral Phasors (HySP) calculations to effectively analyze hyper-spectral time-lapse data. For example, this system may be configured to carry out Hyper-Spectral Phasors (HySP) calculations to effectively analyze five-dimensional (5D) hyper-spectral time-lapse data. Advantages of this imaging system may include: (a) fast computational speed, (b) the ease of phasor analysis, and (c) a denoising algorithm to obtain the minimally-acceptable signal-to-noise ratio (SNR). An unmixed color image of a target may be generated. These images may be used in diagnosis of a health condition, which may enhance a patient's clinical outcome and evolution of the patient's health.
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公开(公告)号：US20200319030A1
公开(公告)日：2020-10-08
申请号：US16833586
申请日：2020-06-04
Applicant: Gustav Hudson
Inventor： Gustav Hudson
Abstract: An improvement is made to a non-Raman spectroscopy method and apparatus in which a quantum entangled transmission package formed in a quantum well in a laser is directed to a target and in which the apparatus receives emission packages from the target. A control circuit triggers the laser to emit a laser beam. The transmission package is sent via the laser beam by an emission fiber and the emission package is received by a collection fiber. The collection fiber and the transmission fiber may be included in a Raman probe. The collection fiber provides an input to a monochromator comprising a diffraction grating. The diffraction grating is constructed to permit selection of any of a wide range of wavelengths. A spectrometer receives an output from the diffraction grating. The spectrometer output is measured by a photomultiplier to provide an input to the control module. A number of different spectra are selectively generated. Also, the transmission package may be formed with a power level to affect structure of a preselected target.
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178.发明授权公开(公告)号：US10794831B2
公开(公告)日：2020-10-06
申请号：US16325354
申请日：2017-08-08
Applicant: HORIBA, Ltd.
Inventor： Chikashi Ota
Abstract: An organic compound analyzer is provided which is capable of highly accurately determining a denaturation feature point on which a minute structural change of an organic compound is reflected. The organic compound analyzer includes an actual measured data storage section, an evaluation criterion vector setting section, a score calculation section, and a change feature point determination section. The actual measured data storage section is configured to store in pairs a plurality of actual measured spectra obtained through measurement of a sample containing an organic compound under a plurality of different external stimulus conditions, and external stimulus conditions under which spectra are respectively measured. The evaluation criterion vector setting section is configured to set a loading that indicates weighting to individual wavenumbers at which the spectra are measured. The score calculation section is configured to calculate a score corresponding to the loading for each of external simulation conditions under which the spectra are measured, on the basis of the loading and the actual measured data. The change feature point determination section is configured to calculate a denaturation temperature of the organic compound on the basis of a change in the score with respect to external stimulus conditions.
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公开(公告)号：US20200300759A1
公开(公告)日：2020-09-24
申请号：US16890950
申请日：2020-06-02
Applicant: The Boeing Company
Inventor： Keith D. Humfeld , Morteza Safai
Abstract: An example system for inspecting a surface includes a laser, an optical system, a gated camera, and a control system. The laser is configured to emit pulses of light, with respective wavelengths of the pulses of light varying over time. The optical system includes at least one optical element, and is configured to direct light emitted by the laser to points along a scan line one point at a time. The gated camera is configured to record a fluorescent response of the surface from light having each wavelength of a plurality of wavelengths at each point along the scan line. The control system is configured to control the gated camera such that an aperture of the gated camera is open during fluorescence of the surface but closed during exposure of the surface to light emitted by the laser.
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公开(公告)号：US20200300704A1
公开(公告)日：2020-09-24
申请号：US16894601
申请日：2020-06-05
Applicant: CANON KABUSHIKI KAISHA
Inventor： Yasuhiro Sekine , Shigeru Ichihara , Yuki Yonetani
Abstract: An identification apparatus includes: a plurality of light capturing units including light-capturing optical systems configured to capture a plurality of Raman scattered light fluxes from a sample, an optical fiber unit configured to include a plurality of optical fibers configured to respectively guide the captured Raman scattered light fluxes and in which the optical fibers are bundled at emission end portions thereof; a spectral element configured to disperse the guided Raman scattered light fluxes; an imaging unit configured to receive the dispersed Raman scattered light fluxes; and a data processor configured to acquire spectral data of the Raman scattered light fluxes from the imaging unit and configured to perform an identification process. The Raman scattered light fluxes dispersed by the spectral element are projected so that a spectral image formed on a light-receiving surface of the imaging unit extends along a main scanning direction of the imaging unit.
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