公开(公告)号：US20240393318A1

公开(公告)日：2024-11-28

申请号：US18694185

申请日：2022-09-19

Applicant: ECOLE POLYTECHNIQUE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE ,  UNIVERSITE PARIS EST CRETEIL VAL DE MARNE

Inventor： Jongwook KIM ,  Thierry GACOIN ,  Marcel FILOCHE ,  Bruno LOUIS ,  Emilie BEQUIGNON

IPC: G01N33/50 ,  C12M1/34 ,  C12M3/06 ,  G01N21/64

Abstract: A method for studying the behaviour of a cell sample contained in a medium containing a plurality of anisotropically shaped nanoparticles dispersed therein, the method including: (i) determining at least one nanoparticle orientation characteristic in a measurement zone at the interface between the fluid medium and the cell sample, the orientation resulting at least partially from the interaction of the fluid medium and the biological material; (ii) determining a mean shear rate characteristic of the fluid medium in the measurement zone from said at least one nanoparticle orientation characteristic determined in this measurement zone; and (iii) determining a characteristic of the cell sample from the mean shear rate thus determined in the measurement zone.

公开(公告)号：US20240316547A1

公开(公告)日：2024-09-26

申请号：US18273542

申请日：2021-01-20

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Fabien SORIN ,  Bastien SCHYRR

IPC: B01L3/00 ,  D01F1/10 ,  D01F8/00

CPC classification number: B01L3/502707 ,  D01F1/10 ,  D01F8/00 ,  B01L2200/12 ,  B01L2300/0838 ,  B01L2300/0845 ,  B01L2300/12 ,  B01L2400/0406 ,  D10B2401/022 ,  D10B2509/00

Abstract: One aspect of the present invention relates to a method of fabricating a chemically active fibre device (1) by thermal drawing. The method comprises the steps of providing a preform, the preform comprising a support element (3) at least partially made of a first polymeric material; and carrying out a thermal drawing process of the preform to produce a thermally drawn fibre. The preform comprises one or more chemically active agents and/or biological materials configured to react with a fluid sample when the one or more chemically active agents and/or biological materials are in contact with the fluid sample. In this manner miniaturised lab-in-fibre devices can be fabricated.

公开(公告)号：US20240299420A1

公开(公告)日：2024-09-12

申请号：US18573519

申请日：2022-06-27

Applicant: Ecole Polytechnique Federale de Lausanne (EPFL)

Inventor： Johan Auwerx ,  Adrienne Mottis ,  Mark Nelson

IPC: A61K31/65 ,  A61P31/16

CPC classification number: A61K31/65 ,  A61P31/16

Abstract: The present invention relates to a method of treating or preventing a viral disease or viral infection comprising administering to a subject a compound of formula (I) or formula (II)

公开(公告)号：US20240266963A1

公开(公告)日：2024-08-08

申请号：US18682393

申请日：2022-08-09

Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Inventor： Drazen Dujic ,  Jakub Kucka

IPC: H02M3/335 ,  H02M1/00 ,  H02M1/08 ,  H02M1/32 ,  H02M1/38 ,  H02M3/00

CPC classification number: H02M3/33571 ,  H02M1/0058 ,  H02M1/08 ,  H02M1/32 ,  H02M1/38 ,  H02M3/01

Abstract: The present invention relates to a method for operating a resonant power converter. The resonant power converter has a primary stage and a secondary stage, at least one of which is actively operated and includes a half-bridge or full-bridge inverter having a pull-up switching device, coupled in parallel with a pull-up antiparallel diode and a pull-down switching device, coupled in parallel with a pull-down antiparallel diode, comprising the steps of alternately turning-off and turning on the pull-up and pull-down switching devices according to a periodic switching scheme, wherein after turning-off one of the switching devices the complementary switching device is respectively turned on after a delay time; and initiating an error handling, if after turning-off of one of the switching devices a non-conductance state of the antiparallel diode of the complementary switching device has been determined.

公开(公告)号：US20240252205A1

公开(公告)日：2024-08-01

申请号：US18564774

申请日：2022-05-27

Applicant: UNIVERSITÉ DE STRASBOURG ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT NATIONAL DES SCIENCES APPLIQUÉES ,  ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Inventor： Lennart RUBBERT ,  Charles BAUR

IPC: A61B17/34 ,  A61B17/00

CPC classification number: A61B17/3417 ,  A61B2017/00309

Abstract: A surgical device, including a tubular outer shaft and an inner element having an elongated shape, the outer shaft comprising a distal and a proximal outer hinges, the inner element comprising an inner hinge, the surgical device having: a first and a second distal stiffnesses considered at the distal outer hinge; and first and second proximal stiffnesses considered at the proximal outer hinge; each of the second distal and proximal stiffnesses being superior to, respectively, the first distal and proximal stiffness; the inner element being able to move angularly and/or axially in the tubular outer shaft, between a first configuration and a second configuration, so that in the first configuration, the surgical device has the second distal stiffness and the first proximal stiffness.

公开(公告)号：US20240228507A1

公开(公告)日：2024-07-11

申请号：US18287063

申请日：2022-04-14

Applicant: ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)

Inventor： Anastasiia KOMAROVA ,  Jeremy LUTERBACHER

IPC: C07D493/14 ,  C07D493/04 ,  C07D493/22

CPC classification number: C07D493/14 ,  C07D493/04 ,  C07D493/22

Abstract: Use of a compound of the general formula (I), (II), (III), (IV), (V) or (VI)




as solvent for chemical reactions, for recrystallizations or extractions.

公开(公告)号：US12003071B2

公开(公告)日：2024-06-04

申请号：US17048921

申请日：2019-04-19

Applicant: ECOLE POLYTECHNIQUE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE PARIS SACLAY

Inventor： Dimitrios Papadopoulos ,  Xavier Delen ,  Frederic Druon

IPC: G02F1/35 ,  G02F1/39 ,  H01S3/00

CPC classification number: H01S3/0057 ,  G02F1/3511 ,  G02F1/3515 ,  G02F1/3519 ,  G02F1/392 ,  H01S3/0071

Abstract: A method for generating ultrashort pulses includes directing a master beam having ultrashort pulses and at least one slave beam through an optical gate material. The intensity of the slave beam upstream of the optical gate material is lower than that of the master beam upstream of the optical gate material. The optical gate material and the pulses of the master beam are chosen to induce a Kerr effect when the master beam passes through the optical gate material, the Kerr effect producing a modulation of the phase of the slave beam in association with pulses of the master beam when the slave beam passes through the optical gate material. The modulation of the phase of the slave beam is transformed into a modulation of the amplitude thereof using a complementary optical device to generate a slave beam downstream of the optical gate material having ultrashort pulses.

公开(公告)号：US20240170232A1

公开(公告)日：2024-05-23

申请号：US18551791

申请日：2022-03-25

Applicant: ECOLE POLYTECHNIQUE ,  ECOLE NATIONALE SUPERIEURE DES TECHNIQUES AVANCEES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Igor ANDRIYASH ,  Cédric THAURY ,  Alessandro FLACCO

IPC: H01H1/54 ,  H01H15/00 ,  H01S3/00

CPC classification number: H01H1/54 ,  H01H15/00 ,  H01S3/0057

Abstract: A method for producing energetic electron beams using a laser-plasma accelerator including a laser and a device for producing a gas cloud in a vacuum chamber, the method including a step of generating a laser pulse which is focused into the gas cloud to create a plasma. The step of generating a laser pulse includes at least the generation of a laser pulse-train with a delay between two successive laser pulses of between three times and thirty times the plasma period TP, such that: TP=λp/c, λp being the plasma wavelength defined by: λp=(2π/C)*(n e2/(m ε0))−½, where c is the speed of light, n is the electron density of the plasma in cm3, e=1.6e−19 C is the charge of an electron, m=9.1e−31 kg is the mass of an electron, and ε0=8.85×10−12 m−3 kg−1 s4 A2 is the permittivity of vacuum.

公开(公告)号：US11989942B2

公开(公告)日：2024-05-21

申请号：US17432907

申请日：2020-02-21

Applicant: Centre National de la Recherche Scientifique ,  Ecole Polytechnique

Inventor： Vincent Bacot ,  Christophe Clanet

IPC: G06V20/40 ,  G06V20/52 ,  G06V40/20

CPC classification number: G06V20/42 ,  G06V20/52 ,  G06V40/23

Abstract: A method for characterizing a dynamic occupancy of a space by two opposing teams of a game, including a movable sporting accessory, such as a ball, a puck or a shuttlecock, each team including at least one player. The method makes it possible to determine, for each player and for all or some of the points on the pitch, a value representative of how far in advance the player is to the point of the pitch, the representative value being computed by a comparison between the duration of movement of the player to the point of the pitch and the duration of movement of a distinct player and/or of the sporting accessory to the same point. A system is also provided for characterizing a dynamic occupancy of a space by two opposing teams of a game, implementing the method.

公开(公告)号：US11953381B2

公开(公告)日：2024-04-09

申请号：US17442976

申请日：2020-02-21

Applicant: UNIVERSITE DE PARIS ,  SORBONNE UNIVERSITE ,  ECOLE POLYTECHNIQUE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

Inventor： Marc Guillon ,  Pascal Berto ,  Dimitris Papadopoulos ,  Gilles Tessier

IPC: G01J9/00

CPC classification number: G01J9/00

Abstract: A method for determining wavefront shapes of a multi-spectral signal light beam from a single signal image acquisition of said multi-spectral signal beam, with a device including an optical assembly made at least of an optical mask and an imaging sensor, notably a matrix imaging sensor, for generating and recording intensity patterns of incident beams, by having these beams reflect on, or propagate through, the optical mask. The optical mask having the optical properties: i) to cause the intensity pattern to depend on the wavefront shape, so that a tilt applied to the wavefront shape results in a displacement amount of the intensity pattern, and ii) to produce uncorrelated intensity patterns over at least one surface area A of the imaging sensor, for a plurality of respective incident monochrome beams of different wavelengths having a same wavefront shape.