公开(公告)号：US20210275696A1

公开(公告)日：2021-09-09

申请号：US17253913

申请日：2019-06-21

Applicant: National Institutes for Quantum and Radiological Science and Technology

Inventor： Takafumi MINAMIMOTO ,  Yuji NAGAI ,  Bin JI ,  Naohisa MIYAKAWA ,  Makoto HIGUCHI ,  Tetsuya SUHARA

IPC: A61K51/04 ,  C07D243/38 ,  C07B59/00

Abstract: The purpose of the present invention is to provide a technique for imaging the brain of a live animal and application of the technique. A radiolabeled dibenzoazepine derivative, which shows excellent brain parmeability, high receptor selectivity and high quantitativity, is used for imaging a live animal body. A dibenzoazepine derivative is used for treating a disease in which hM4D receptor or hM3D receptor participates. Further, a radiolabeled dibenzoazepine derivative is used for imaging an axonal end which is innervated by a nerve cell.

公开(公告)号：US20210128089A1

公开(公告)日：2021-05-06

申请号：US17081564

申请日：2020-10-27

Applicant: CANON MEDICAL SYSTEMS CORPORATION ,  National Institutes for Quantum and Radiological Science and Technology ,  General Incorporated Association The Japan-Multinational Trial Organization

Inventor： Shunsuke FUJIWARA ,  Yasuo SAKURAI ,  Ming-Rong ZHANG ,  Lin XIE ,  Masayuki FUJINAGA ,  Masayuki HANYU ,  Cheng-Long HUANG ,  Masakazu FUKUSHIMA ,  Hiromi WADA

IPC: A61B6/00

Abstract: An analysis apparatus according to an embodiment includes an extraction unit, a calculation unit, and an evaluation unit. The extraction unit extracts a detection value in a tumor region, a blood region, and a muscle region from a nuclear medicine image of a subject administered with a drug containing a radiolabeled anticancer drug that works by accumulating in a tumor. The calculation unit calculates a first comparison value that is a comparison result between the detection value in the blood region and the detection value in the tumor region, and a second comparison value that is a comparison result between the detection value in the muscle region and the detection value in the tumor region. The evaluation unit evaluates an accumulation of the drug in the tumor, based on the first comparison value and the second comparison value calculated by the calculation unit.

公开(公告)号：US20210085186A1

公开(公告)日：2021-03-25

申请号：US17053274

申请日：2019-04-26

Applicant: National Institutes for Quantum and Radiological Science and Technology ,  Light Touch Technology Incorporated

Inventor： Koichi YAMAKAWA ,  Makoto AOYAMA ,  Takamitsu MORIOKA ,  Tatsuhiko IMAOKA ,  Kanade OGAWA

IPC: A61B5/00 ,  A61B1/00 ,  A61B1/06 ,  A61B5/06 ,  A61B5/20

Abstract: A control section as a tissue identification device includes: an absorbance ratio calculating section configured to calculate the ratio of an absorbance indicated by a transmitted portion of first inspection light transmitted through biological tissue to an absorbance indicated by a transmitted portion of second inspection light transmitted through the biological tissue; and an identification information generating section configured to generate identification information indicative of the type or state of the biological tissue by determining within which of a plurality of preset numerical ranges the ratio falls.

公开(公告)号：US20200249288A1

公开(公告)日：2020-08-06

申请号：US16647884

申请日：2019-03-22

Applicant: National Institutes for Quantum and Radiological Science and Technology

Inventor： Toshiya INAMI ,  Tetsu WATANUKI ,  Tetsuro UENO ,  Ryo YASUDA

IPC: G01R33/12 ,  H01J37/26 ,  H01J37/22 ,  G01R33/032 ,  G01N23/2252

Abstract: A magnetic material observation method in accordance with the present invention includes: an irradiating step including irradiating a region of a sample with an excitation beam and thereby allowing a magnetic element contained in the sample to radiate a characteristic X-ray; a detecting step including detecting intensities of a right-handed circularly polarized component and a left-handed circularly polarized component contained in the characteristic X-ray; and a calculating step including calculating the difference between the intensity of the right-handed circularly polarized component and the intensity of the left-handed circularly polarized component. Reference to such a difference enables precise measurement of the direction or magnitude of magnetization without strict limitations as to the sample.

公开(公告)号：US20200220318A1

公开(公告)日：2020-07-09

申请号：US16641803

申请日：2018-08-24

Applicant: National Institutes for Quantum and Radiological Science and Technology

Inventor： Yutaka AKAHANE ,  Makoto AOYAMA ,  Kanade OGAWA ,  Koichi YAMAKAWA

IPC: H01S3/11 ,  G01N21/59 ,  G01N21/55 ,  H01S3/094 ,  H01S3/16 ,  G02F1/39 ,  H01S3/0941

Abstract: Provided is a laser device in which: a laser medium doped with ytterbium emits light upon absorption of excitation light; the light emitted by the laser medium is amplified to obtain output light; and the output light is outputted in the form of a plurality of pulses. In the laser device, a spatial filter is disposed in the optical path of the light emitted by the laser medium or is disposed in the optical path of the output light outputted from an optical resonator, the spatial filter being configured to filter out a portion of the light or of the output light around the optical axis.

公开(公告)号：US10533130B2

公开(公告)日：2020-01-14

申请号：US16415083

申请日：2019-05-17

Applicant: Denka Company Limited ,  National Institutes For Quantum And Radiological Science And Technology ,  National University Corporation Gunma University

Inventor： Wataru Kada ,  Kenta Miura ,  Osamu Hanaizumi ,  Tomihiro Kamiya ,  Takahiro Satoh ,  Junichi Susaki ,  Suzuya Yamada

IPC: C09K11/64 ,  G01T1/20 ,  G01T1/202 ,  C09K11/77 ,  C09K11/70

Abstract: Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.

公开(公告)号：US10315052B2

公开(公告)日：2019-06-11

申请号：US15129749

申请日：2015-03-25

Applicant: National Institutes for Quantum and Radiological Science and Technology

Inventor： Hiroaki Matubara ,  Naruhiro Matufuji

IPC: A61B5/00 ,  A61N5/10 ,  G06T7/00 ,  G06T7/90

Abstract: Provided is a prediction device for skin change from radiation exposure, the device being capable of precisely predicting a skin reaction to radiation exposure. Also provided are a verification device, a program for the prediction device for skin change, and a program for the verification device.A prediction device (4) for skin change from radiation exposure includes: a radiation information accepting unit (11) that accepts input of radiation information regarding expected exposure to radiation; a pre-exposure skin image acquiring unit (21) that acquires a skin image that captures skin of a living body; a change computing unit that computes the change of the skin due to exposure to the radiation determined by the radiation information and that obtains from the skin image a post-change prediction skin image; and a prediction skin image outputting unit (25) that outputs the prediction skin image. The change calculating unit includes an expression form converting unit (22), an amount-of-change deciding unit (13), an image changing unit (23), and an expression form restoring unit (24).

公开(公告)号：US20190032230A1

公开(公告)日：2019-01-31

申请号：US16073546

申请日：2017-01-26

Applicant: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY

Inventor： Tsuyoshi HOSHINO

IPC: C25B7/00 ,  B01D61/46 ,  C01D15/08 ,  C02F1/469 ,  B01D71/02 ,  C25B1/10 ,  C25B9/10 ,  C22B26/12

Abstract: The disclosure relates to recovering Li ions in a raw liquid into a recovery liquid at a high recovery speed. A lithium selective permeable membrane is constituted of a selective permeable membrane main body constituted of a lithium ion superconductor (ion conductor) having a particularly high ion conductivity and a Li adsorption layer formed as a thin layer on a raw liquid side (a first electrode) thereof. As a material constituting the selective permeable membrane main body, specifically, lanthanum lithium titanium oxide can be used. The Li adsorption layer is formed as a thin layer on a surface of the selective permeable membrane main body by carrying out a chemical treatment on the selective permeable membrane main body.

公开(公告)号：US20180244990A1

公开(公告)日：2018-08-30

申请号：US15756160

申请日：2016-08-25

Applicant: National University Corporation Gunma University ,  National Institutes for Quantum and Radiological Science And Technology ,  Denka Company Limited

Inventor： Wataru Kada ,  Kenta Miura ,  Osamu Hanaizumi ,  Tomihiro Kamiya ,  Takahiro Satoh ,  Junichi Susaki ,  Suzuya Yamada

IPC: C09K11/64 ,  G01T1/202 ,  C09K11/70

CPC classification number: C09K11/64 ,  C09K11/70 ,  C09K11/7734 ,  G01T1/20 ,  G01T1/202 ,  G01T1/2023

Abstract: [Problem] To provide highly heat-resistant and radiation-resistant radiation measuring equipment.[Solution] Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.

公开(公告)号：US20170229281A1

公开(公告)日：2017-08-10

申请号：US15497831

申请日：2017-04-26

Applicant: NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY ,  KABUSHIKI KAISHA TOSHIBA

Inventor： Takuji FURUKAWA ,  Shigeki TAKAYAMA ,  Takashi YAZAWA ,  Yoshiharu KANAI ,  Kosuke SATO ,  Tomofumi ORIKASA ,  Kei KOYANAGI

IPC: H01J37/147 ,  A61N5/10

CPC classification number: A61N5/1043 ,  A61N2005/1087 ,  G21K1/093 ,  G21K5/04 ,  H01F7/202

Abstract: A charged particle beam irradiation apparatus according to an embodiment includes: a first scanning electromagnet device configured to deflect a charged particle beam to a second direction that is substantially perpendicular to a first direction along which the charged particle beam enters, the first scanning electromagnet device having an aperture on an outlet side larger than that on an inlet side; and a second scanning electromagnet device configured to deflect the charged particle beam to a third direction that is substantially perpendicular to the first direction and the second direction, the second scanning electromagnet device having an aperture on an outlet side larger than that on an inlet side, the first scanning electromagnet device and the second scanning electromagnet device being disposed to be parallel with the first direction.