公开(公告)号：US20150302135A1

公开(公告)日：2015-10-22

申请号：US14690227

申请日：2015-04-17

Applicant: Chul-Hong PARK ,  Sang-Hoon BAEK ,  Su-Hyeon KIM ,  Kyoung-Yun BAEK ,  Sung-Wook AHN ,  Sang-Kyu OH ,  Seung-Jae JUNG

Inventor： Chul-Hong PARK ,  Sang-Hoon BAEK ,  Su-Hyeon KIM ,  Kyoung-Yun BAEK ,  Sung-Wook AHN ,  Sang-Kyu OH ,  Seung-Jae JUNG

IPC: G06F17/50

CPC classification number: G06F17/5081 ,  G06F17/5072

Abstract: A method of manufacturing an integrated circuit, a system for carrying out the method, and a system for verifying an integrated circuit may use a standard cell layout including a first layout region that may violate design rules. The method for designing an integrated circuit may comprise receiving a data file that includes a scaling enhanced circuit layout, and designing a first standard cell layout using design rules and the data file. The designing the first standard cell layout may include designing a first layout region of the first standard cell layout using the data file, and designing a second region of the first standard cell layout using the design rules.

Abstract translation: 集成电路的制造方法，用于实施该方法的系统以及用于验证集成电路的系统可以使用包括可能违反设计规则的第一布局区域的标准单元布局。 用于设计集成电路的方法可以包括接收包括缩放增强电路布局的数据文件，以及使用设计规则和数据文件来设计第一标准单元布局。 设计第一标准单元布局可以包括使用数据文件设计第一标准单元布局的第一布局区域，以及使用设计规则设计第一标准单元布局的第二区域。

公开(公告)号：US08724105B2

公开(公告)日：2014-05-13

申请号：US13160854

申请日：2011-06-15

Applicant: June-young Lee ,  Hee-jeong Jeong ,  Seong-ho Cho ,  Su-hyeon Kim

Inventor： June-young Lee ,  Hee-jeong Jeong ,  Seong-ho Cho ,  Su-hyeon Kim

IPC: G01N1/10 ,  B82Y15/00 ,  B01L3/00

CPC classification number: G01N1/10 ,  B01L3/502707 ,  B32B37/065 ,  B32B37/12 ,  B32B38/06 ,  B32B2535/00 ,  B82Y15/00 ,  G01N21/554 ,  G01N21/645 ,  Y10S977/953 ,  Y10S977/957 ,  Y10S977/958

Abstract: A nano particle tracking device includes a channel structure. The channel structure of the nano particle tracking device includes a pair of microchannels in which a specimen including nano particles is accommodated and which face each other, at least one nano channel which is between the pair of microchannels, which connects the pair of microchannels to each other and through which the nano particles in the specimen are moved, and a nano grating below the nano channel and crossing the nano channel perpendicularly.

Abstract translation: 纳米粒子跟踪装置包括通道结构。 纳米颗粒跟踪装置的通道结构包括一对微通道，其中包含纳米颗粒的样品被容纳并且彼此面对，在一对微通道之间的至少一个纳米通道，将一对微通道连接到每个微通道 样品中的纳米颗粒通过其移动，并且纳米通道下方的纳米光栅并且垂直穿过纳米通道。

公开(公告)号：US20130122577A1

公开(公告)日：2013-05-16

申请号：US13577418

申请日：2011-02-07

Applicant: Joo-won Rhee ,  Su-hyeon Kim ,  Jeong-gun Lee ,  Mi-jeong Song

Inventor： Joo-won Rhee ,  Su-hyeon Kim ,  Jeong-gun Lee ,  Mi-jeong Song

IPC: C12Q1/68

CPC classification number: C12Q1/6869 ,  B82Y15/00 ,  G01N33/5308 ,  Y10S977/774 ,  Y10S977/92 ,  C12Q2522/101 ,  C12Q2563/107

Abstract: Provided are kits for determining a nucleotide sequence of a target nucleic acid, the kit including at least one sequence specific binding protein and a detectable tag. In accordance with a kit for determining a nucleotide sequence of a target nucleic acid according to one exemplary embodiment and a method and device for determining a nucleotide sequence of a target nucleic acid, the nucleotide sequence of the target nucleic acid may be more efficiently determined.

Abstract translation: 提供了用于确定靶核酸的核苷酸序列的试剂盒，该试剂盒包括至少一种序列特异性结合蛋白和可检测标签。 根据一个示例性实施方案的用于确定靶核酸的核苷酸序列的试剂盒以及用于确定靶核酸的核苷酸序列的方法和装置，可以更有效地确定靶核酸的核苷酸序列。

公开(公告)号：US08361717B2

公开(公告)日：2013-01-29

申请号：US12580325

申请日：2009-10-16

Applicant: Su-hyeon Kim

Inventor： Su-hyeon Kim

IPC: C12Q1/68 ,  C12M1/00 ,  C07H21/02 ,  C07H21/04

CPC classification number: C12Q1/6874

Abstract: Provided are magnetic particles for nucleic acid sequencing and a method of sequencing nucleic acid using the same. The nucleotide sequence of a target nucleic acid may be efficiently determined using the magnetic particles and the method of sequencing nucleic acid using the same.

Abstract translation: 提供用于核酸测序的磁性颗粒和使用其进行核酸测序的方法。 靶核酸的核苷酸序列可以使用磁性粒子和使用其进行核酸测序的方法有效地测定。

公开(公告)号：US20120225457A1

公开(公告)日：2012-09-06

申请号：US13294596

申请日：2011-11-11

Applicant: June-young LEE ,  Jwa-min NAM ,  Su-hyeon KIM ,  Woo-chang LEE ,  Jae-young KIM ,  Joo-won RHEE ,  Young-kwang LEE ,  Dong-kwon LIM ,  Jae-ho HWANG

Inventor： June-young LEE ,  Jwa-min NAM ,  Su-hyeon KIM ,  Woo-chang LEE ,  Jae-young KIM ,  Joo-won RHEE ,  Young-kwang LEE ,  Dong-kwon LIM ,  Jae-ho HWANG

IPC: C12P19/34 ,  B32B5/16 ,  C07H21/00 ,  B82Y99/00

CPC classification number: C07H21/00 ,  B82Y15/00 ,  C12P19/34 ,  Y10T428/2991

Abstract: A nanoparticle-nucleic acid complex and a method of linearizing a target nucleic acid by using the nanoparticle-nucleic acid complex are disclosed. By using the nanoparticle-nucleic acid complex and the method, nucleotide sequence analysis and mapping of a target nucleic acid may be efficiently performed.

Abstract translation: 公开了纳米颗粒 - 核酸复合物和通过使用纳米颗粒 - 核酸复合物线性化靶核酸的方法。 通过使用纳米粒子 - 核酸复合物和该方法，可以有效地进行目标核酸的核苷酸序列分析和作图。

公开(公告)号：US07943369B2

公开(公告)日：2011-05-17

申请号：US11517090

申请日：2006-09-07

Applicant: In Ho Lee ,  Jun Hong Min ,  Su Hyeon Kim ,  Chin Sung Park ,  Ah gi Kim ,  Kui Hyun Kim

Inventor： In Ho Lee ,  Jun Hong Min ,  Su Hyeon Kim ,  Chin Sung Park ,  Ah gi Kim ,  Kui Hyun Kim

IPC: C12M1/34

CPC classification number: G01N33/5308

Abstract: A DNA (Deoxyribo Nucleic Acid) detection device and a manufacturing method thereof detects DNA by an electrical method without a separate process for detection by using semiconductor microfabrication techniques. The DNA detection device includes a pair of chambers formed on a semiconductor substrate for accommodating a detection sample, a channel connecting the pair of chambers and a lid covering the pair of chambers. According to the present invention, it is possible to attain a DNA detection device, which can be mass-produced from a silicon substrate by using semiconductor manufacturing technology with improved microfabrication techniques, and a manufacturing method thereof.

Abstract translation: DNA（脱氧核糖核酸）检测装置及其制造方法，通过使用半导体微细加工技术，不用单独的检测方法，通过电气方式检测DNA。 DNA检测装置包括形成在用于容纳检测样品的半导体基板上的一对室，连接该对室的通道和覆盖该对室的盖。 根据本发明，可以通过使用具有改进的微细加工技术的半导体制造技术来获得可以从硅基板批量生产的DNA检测装置及其制造方法。

公开(公告)号：US07910343B2

公开(公告)日：2011-03-22

申请号：US12059250

申请日：2008-03-31

Applicant: Su-hyeon Kim ,  Jeong-gun Lee

Inventor： Su-hyeon Kim ,  Jeong-gun Lee

IPC: C12N13/00

CPC classification number: C12M47/06 ,  B01L3/5027 ,  C12N1/066 ,  C12N13/00 ,  G01N1/44 ,  Y10T137/2496 ,  Y10T436/25

Abstract: A cell lysis device for lysing cells or viruses, comprising a cell lysis tube having a sample inlet; a pump connected to the cell lysis tube for transferring a sample into the tube; a sealing unit for reversibly sealing a specific region of the tube; and a laser source for generating a laser is provide. Further, a method of lysing cells or viruses using the cell lysis device is provide. The method comprises introducing a sample containing cells or viruses and optionally magnetic beads to the cell lysis tube through the sample inlet; transferring the sample to a specific region in the cell lysis tube by means of the pump; temporarily sealing the region of the cell lysis tube where the sample is placed with the sealing unit; irradiating the sample with the laser; removing the sealing unit from the cell lysis tube; and discharging the sample from the cell lysis tube by means of the pump.

Abstract translation: 一种用于裂解细胞或病毒的细胞裂解装置，包括具有样品入口的细胞裂解管; 连接到细胞裂解管的泵，用于将样品转移到管中; 用于可逆地密封管的特定区域的密封单元; 并提供用于产生激光的激光源。 此外，提供使用细胞裂解装置裂解细胞或病毒的方法。 该方法包括通过样品入口将含有细胞或病毒的样品和任选的磁珠引入细胞裂解管; 通过泵将样品转移到细胞裂解管中的特定区域; 用密封单元临时密封放置样品的细胞溶解管的区域; 用激光照射样品; 从细胞裂解管中取出密封单元; 并通过泵从细胞裂解管中排出样品。

公开(公告)号：US07790109B2

公开(公告)日：2010-09-07

申请号：US11625877

申请日：2007-01-23

Applicant: Su-hyeon Kim ,  Jin-tae Kim ,  Kak Namkoong ,  In-ho Lee ,  Chin-sung Park ,  Young-sun Lee

Inventor： Su-hyeon Kim ,  Jin-tae Kim ,  Kak Namkoong ,  In-ho Lee ,  Chin-sung Park ,  Young-sun Lee

IPC: G01N15/06 ,  G01N33/00 ,  G01N33/48 ,  B01J10/00 ,  B01J10/02 ,  B01J12/00 ,  B01J12/02 ,  F15C1/04 ,  F15C3/00 ,  F15C1/06

CPC classification number: B01L3/502738 ,  B01L7/52 ,  B01L2200/0689 ,  B01L2300/0816 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2400/0655 ,  B29C33/3857 ,  B29C33/60 ,  Y10T137/218 ,  Y10T137/2202 ,  Y10T137/2224

Abstract: A micro-fluid reaction vessel includes an upper plate formed of an elastomer, a lower plate adhered to the upper plate, a micro-chamber and a micro-channel formed on an inner surface of the upper plate facing the lower plate and an inlet hole and an outlet hole formed in the upper plate and through which a fluid flows into or out of, respectively. The micro-channel is constructed to be closed by pressure applied to the upper plate and elastically restored when the pressure is not applied. A micro fluid reaction method uses the micro fluid reaction vessel and a method of manufacturing forms the microfluid reaction vessel.

Abstract translation: 微流体反应容器包括由弹性体形成的上板，粘附到上板的下板，形成在面向下板的上板的内表面上的微室和微通道，以及入口孔 以及形成在上板中并且流体分别流入或流出的出口孔。 微通道被构造为通过施加到上板的压力而关闭，并且当不施加压力时弹性恢复。 微流体反应方法使用微流体反应容器和制造方法形成微流体反应容器。

公开(公告)号：US20100204065A1

公开(公告)日：2010-08-12

申请号：US12762596

申请日：2010-04-19

Applicant: Su-hyeon KIM ,  In-ho LEE ,  Jun-hong MIN

Inventor： Su-hyeon KIM ,  In-ho LEE ,  Jun-hong MIN

IPC: C40B50/14

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00369 ,  B01J2219/00432 ,  B01J2219/005 ,  B01J2219/0052 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00657 ,  B01J2219/00673 ,  B01J2219/00677 ,  B01J2219/00711 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00729 ,  B01J2219/00743

Abstract: A microarray including hydrogel and a plurality of probes which are immobilized in discrete regions of the hydrogel, and a method of preparing the same are provided. When using the microarray and method, a solid substrate is not required and many biomolecules can be immobilized in a small volume, thereby obtaining high sensitivity. Since gel can be cut to obtain many pieces, many microarrays can be prepared at once.

Abstract translation: 提供了包含水凝胶和固定在水凝胶的离散区域中的多个探针的微阵列及其制备方法。 当使用微阵列和方法时，不需要固体底物，并且许多生物分子可以以小体积固定，从而获得高灵敏度。 由于可以切割凝胶以获得许多片，因此可以一次制备许多微阵列。

公开(公告)号：US20090099782A1

公开(公告)日：2009-04-16

申请号：US12128680

申请日：2008-05-29

Applicant: Su-hyeon KIM ,  Yoon-kyoung CHO ,  Jeong-gun LEE

Inventor： Su-hyeon KIM ,  Yoon-kyoung CHO ,  Jeong-gun LEE

IPC: G01N33/50

CPC classification number: G01N35/00732 ,  G01N35/00069 ,  G01N35/08 ,  G01N2035/00752 ,  Y10T436/11

Abstract: Provided are an automatic analyzing method and apparatus for a microfludic system. The apparatus includes means for recognizing a disc or chip in the microfludic system, performs an operation and detection by automatically loading a DB according to a recognized type, and perform quantitation of a test.

Abstract translation: 本发明提供一种微流体系统的自动分析方法和装置。 该装置包括用于识别微流体系统中的盘或芯片的装置，通过根据识别的类型自动加载数据库进行操作和检测，并执行测试的定量。