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公开(公告)号：US20180104694A1
公开(公告)日：2018-04-19
申请号：US15724203
申请日：2017-10-03
Applicant: ABBOTT LABORATORIES
Inventor： Jeffrey B. Huff , Mark A. Hayden , Peter J. Karabatsos , Andrew Fischer , John M. Robinson , Shelley R. Holets-McCormack , Sophie Laurenson
CPC classification number: B01L3/502784 , B01L3/502707 , B01L3/502715 , B01L3/502761 , B01L2200/0668 , B01L2200/0689 , B01L2200/10 , B01L2200/142 , B01L2300/0829 , B01L2300/0858 , B01L2300/0887 , B01L2300/089 , B01L2300/0893 , B01L2300/12 , B01L2300/161 , G01N33/5302 , G01N33/54373
Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.
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公开(公告)号：US11633738B2
公开(公告)日：2023-04-25
申请号：US15724203
申请日：2017-10-03
Applicant: ABBOTT LABORATORIES
Inventor： Jeffrey B. Huff , Mark A. Hayden , Peter J. Karabatsos , Andrew Fischer , John M. Robinson , Shelley R. Holets-McCormack , Sophie Laurenson
IPC: B01L3/00 , G01N33/543 , G01N33/53
Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.
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13.发明申请公开(公告)号：US20210338856A1
公开(公告)日：2021-11-04
申请号：US17375737
申请日：2021-07-14
Applicant: Abbott Laboratories
Inventor： Patrick Fritchie , Pathik Soni , Lei Qiao , Dustin House , Lyle Yarnell , Edna Prieto-Ballengee , Cathy Forsythe , Michael Shawn Murphy , Andrew Fischer , Akanksha Sharma , Joseph Esposito , Matt Effinger , Michael Futer
Abstract: Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit, the tank circuit including a work coil and a sense coil. The sense coil is to detect a magnetic field generated by the work coil and to output signals in response to the detection. The example system includes a controller to cause the tank circuit to oscillate at a resonant frequency in response to the signals and a power drive unit in communication with the controller and the induction heater. The power drive unit is to adjust power provided to the induction heater in response to the controller driving the tank circuit to oscillate at the resonant frequency.
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公开(公告)号：US10913064B2
公开(公告)日：2021-02-09
申请号：US14687398
申请日：2015-04-15
Applicant: Abbott Laboratories
Inventor： Andrew Fischer , Adrian Petyt , Sophie Laurenson
Abstract: Example methods, apparatus, systems for droplet actuator fabrication are disclosed. An example method disclosed herein for making a droplet actuator includes ablating a first substrate with a laser to form an electrode array on the first substrate. The example method includes applying at least one of hydrophobic or a dielectric material to the electrode array. The example method also includes aligning the first substrate with a second substrate. The second substrate includes a second treated layer. In the example method, the alignment includes a gap between at least a portion of the first treated layer and at least a portion the second treated layer.
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公开(公告)号：US10369565B2
公开(公告)日：2019-08-06
申请号：US14976684
申请日：2015-12-21
Applicant: Abbott Laboratories
Inventor： Andrew Fischer
IPC: B01L3/00
Abstract: Example methods, apparatus, systems for diluting samples are disclosed. An example method includes depositing a first fluid droplet on a first electrode of a plurality of electrodes. The first electrode has a first area. The first fluid droplet has a first volume associated with the first area. The example method includes depositing a second fluid droplet on a second electrode of the plurality of electrodes. The second electrode has a second area. The second fluid droplet has a second volume associated with the second area. The second volume is different than the first volume. The example method includes forming a combined droplet by selectively activating at least one of the first electrode or the second electrode to cause one of the first fluid droplet or the second fluid droplet to merge with the other of the first fluid droplet or the second fluid droplet.
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Patent Agency Ranking
公开(公告)号：US09821321B2
公开(公告)日：2017-11-21
申请号：US15339023
申请日：2016-10-31
Applicant: Abbott Laboratories
Inventor： Andrew Fischer
IPC: G01N27/414 , B03C5/00 , G01N27/327 , G01N27/447 , G01N33/543
CPC classification number: B03C5/005 , B01L2200/0631 , B01L2200/0694 , B01L2200/10 , B01L2300/0636 , B01L2400/0415 , G01N27/3275 , G01N27/4145 , G01N27/4146 , G01N27/44791 , G01N33/5438
Abstract: Example apparatus, systems and methods to desalt a sample are disclosed. An example method includes introducing a sample into an apparatus, in which the apparatus includes a sensor coupled to a substrate and an electrode. The example method also includes applying, via the electrode, an electric potential to the sample to redistribute ions in the sample relative to the sensor.
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公开(公告)号：US20170043355A1
公开(公告)日：2017-02-16
申请号：US15339023
申请日：2016-10-31
Applicant: Abbott Laboratories
Inventor： Andrew Fischer
IPC: B03C5/00 , G01N27/447 , G01N33/543 , G01N27/414
CPC classification number: B03C5/005 , B01L2200/0631 , B01L2200/0694 , B01L2200/10 , B01L2300/0636 , B01L2400/0415 , G01N27/3275 , G01N27/4145 , G01N27/4146 , G01N27/44791 , G01N33/5438
Abstract: Example apparatus, systems and methods to desalt a sample are disclosed. An example method includes introducing a sample into an apparatus, in which the apparatus includes a sensor coupled to a substrate and an electrode. The example method also includes applying, via the electrode, an electric potential to the sample to redistribute ions in the sample relative to the sensor.
Abstract translation: 公开了脱盐样品的示例性设备，系统和方法。 示例性方法包括将样品引入到装置中，其中该装置包括耦合到基板和电极的传感器。 该示例性方法还包括通过电极向样品施加电势以相对于传感器重新分布样品中的离子。
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公开(公告)号：US12201980B2
公开(公告)日：2025-01-21
申请号：US17094423
申请日：2020-11-10
Applicant: Abbott Laboratories
Inventor： Andrew Fischer , Adrian Petyt , Sophie Laurenson
Abstract: Example methods, apparatus, systems for droplet actuator fabrication are disclosed. An example non-transitory computer readable medium includes instructions that, when executed, cause at least one processor to at least control movement of a laser to cause the laser to etch an electrode pattern in a first substrate, the electrode pattern including a first set of electrodes, a second set of electrodes, and a third set of electrodes; control a printer driver to cause a hydrophobic material and a dielectric material to be applied to the second set of electrodes and not the first set of electrodes via a printer; control a bonding driver to cause a gap to be defined between the first substrate and a second substrate; and control a dicing driver to cause a portion the first substrate and a portion of the second substrate to be cut into a droplet actuator.
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公开(公告)号：US11185858B2
公开(公告)日：2021-11-30
申请号：US16531253
申请日：2019-08-05
Applicant: Abbott Laboratories
Inventor： Andrew Fischer
IPC: B01L3/00
Abstract: Example methods, apparatus, systems for diluting samples are disclosed. An example method includes depositing a first fluid droplet on a first electrode of a plurality of electrodes. The first electrode has a first area. The first fluid droplet has a first volume associated with the first area. The example method includes depositing a second fluid droplet on a second electrode of the plurality of electrodes. The second electrode has a second area. The second fluid droplet has a second volume associated with the second area. The second volume is different than the first volume. The example method includes forming a combined droplet by selectively activating at least one of the first electrode or the second electrode to cause one of the first fluid droplet or the second fluid droplet to merge with the other of the first fluid droplet or the second fluid droplet.
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公开(公告)号：US10052639B2
公开(公告)日：2018-08-21
申请号：US15816755
申请日：2017-11-17
Applicant: Abbott Laboratories
Inventor： Andrew Fischer
IPC: G01N27/414 , B03C5/00 , G01N27/327 , G01N33/543 , G01N27/447
CPC classification number: B03C5/005 , B01L2200/0631 , B01L2200/0694 , B01L2200/10 , B01L2300/0636 , B01L2400/0415 , G01N27/3275 , G01N27/4145 , G01N27/4146 , G01N27/44791 , G01N33/5438
Abstract: Example apparatus, systems and methods to desalt a sample are disclosed. An example method includes introducing a sample into an apparatus, in which the apparatus includes a sensor coupled to a substrate and an electrode. The example method also includes applying, via the electrode, an electric potential to the sample to redistribute ions in the sample relative to the sensor.
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