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11.发明申请公开(公告)号：US20210308028A1
公开(公告)日：2021-10-07
申请号：US17301257
申请日：2021-03-30
Applicant: Colgate-Palmolive Company
Inventor： Ying Yang , James Masters , Harsh Mahendra Trivedi , Tulika Sarma
Abstract: Method of improving tissue integrity of tissue that functions as a barrier are provided. Method of protecting and maintaining tissue integrity of tissue that functions as a barrier are provided. Method of repairing damage to tissue that functions as a barrier, and to restoring and improving function of such damaged tissue are provided. Methods of improving, maintaining, protecting, repairing and/or restoring the integrity of tissue which functions as a barrier and repair of damage to and healing of wounds to such tissue improves, maintains, protects, repairs and restores immunity. The methods comprising contacting the tissue with an effective amount of a composition comprising one or more sources of zinc ions such as zinc oxide, zinc citrate, or combination thereof zinc oxide and zinc citrate, and optionally further comprising arginine and/or one or more neutral amino acids.
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公开(公告)号：US10335615B2
公开(公告)日：2019-07-02
申请号：US15629190
申请日：2017-06-21
Applicant: Colgate-Palmolive Company
Inventor： Ying Yang , Dandan Chen , Robert D'Ambrogio , Paul Thomson , Harsh Mahendra Trivedi , Michael Prencipe , James Masters , Stanislav Jaracz
IPC: A61K8/21 , A61K8/22 , A61K8/27 , A61K8/34 , A61K8/35 , A61K8/97 , A61K45/06 , A61K8/365 , A61Q11/00 , A61Q17/00 , A61K36/9068
Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.
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公开(公告)号：US09993414B2
公开(公告)日：2018-06-12
申请号：US14652785
申请日：2012-12-17
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Katherine Hu , Guofeng Xu , Paul Joseph Vincenti
CPC classification number: A61K8/60 , A61K2800/92 , A61Q11/00
Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.
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公开(公告)号：US09901523B2
公开(公告)日：2018-02-27
申请号：US14653885
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： Guofeng Xu , Zhiqiang Liu , Long Pan , LaTonya Kilpatrick-Liverman , Ying Yang , Michael A. Stranick , Zhigang Hao
CPC classification number: A61K8/27 , A61K8/20 , A61K8/21 , A61K8/44 , A61K2800/58 , A61K2800/92 , A61Q11/00
Abstract: Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
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公开(公告)号：US20170368376A1
公开(公告)日：2017-12-28
申请号：US15629190
申请日：2017-06-21
Applicant: Colgate-Palmolive Company
Inventor： Ying Yang , Dandan CHEN , Robert D'AMBROGIO , Paul THOMSON , Harsh Mahendra TRIVEDI , Michael PRENCIPE , James MASTERS , Stanislav JARACZ
CPC classification number: A61Q11/00 , A61K8/21 , A61K8/22 , A61K8/27 , A61K8/34 , A61K8/347 , A61K8/35 , A61K8/365 , A61K8/97 , A61K36/9068 , A61K45/06 , A61Q17/005
Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.
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Patent Agency Ranking
公开(公告)号：US20150328120A1
公开(公告)日：2015-11-19
申请号：US14652785
申请日：2012-12-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Katherine Hu , Guofeng Xu , Paul Joseph Vincenti
CPC classification number: A61K8/60 , A61K2800/92 , A61Q11/00
Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.
Abstract translation: 本发明涉及口腔护理组合物和抑制微生物生物膜形成和/或降解微生物生物膜的方法。 本文公开了包含具有葡萄糖部分和氨基酸部分的阿马多里化合物的口腔护理组合物。 阿马多利化合物可用于抑制口腔微生物生物膜形成和/或降解哺乳动物受试者口腔中的口腔微生物生物膜。
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17.发明申请公开(公告)号：US20150328096A1
公开(公告)日：2015-11-19
申请号：US14653876
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： LaTonya Kirkpatrick-Liverman , Zhiqiang Liu , Long Pan , Ying Yang , Guofeng Xu , Michael A. Stranick , Zhigang Hao
IPC: A61K8/27 , C07C229/12 , A61Q11/00 , A61K8/44 , A61K8/21
CPC classification number: A61K8/27 , A61K8/21 , A61K8/416 , A61K8/44 , A61K2800/74 , A61Q11/00 , C07C229/12
Abstract: The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
Abstract translation: 本发明提供包含游离或口服可接受的盐形式的四元卤化锌和三甲基甘氨酸的混合物的口腔护理组合物。 还提供了制备和使用组合物的方法。
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公开(公告)号：US10773105B2
公开(公告)日：2020-09-15
申请号：US16425312
申请日：2019-05-29
Applicant: Colgate-Palmolive Company
Inventor： Ying Yang , Dandan Chen , Robert D'Ambrogio , Paul Thomson , Harsh Mahendra Trivedi , Michael Prencipe , James Masters , Stanislav Jaracz
IPC: A61Q11/00 , A61K8/34 , A61K8/35 , A61K8/365 , A61Q17/00 , A61K8/21 , A61K8/22 , A61K8/27 , A61K8/97 , A61K36/9068 , A61K45/06
Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.
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公开(公告)号：US09943473B2
公开(公告)日：2018-04-17
申请号：US14653292
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Jairajh Mattai , Shamim Ansari , Jianhong Qiu , James G. Masters , Ying Yang
CPC classification number: A61K8/58 , A61K8/27 , A61K8/44 , A61Q15/00 , A61Q17/005
Abstract: The invention provides a personal care composition for application to the skin which comprises a personal care composition for application to the skin or hair comprising a zinc X halide and a cosmetically acceptable base, wherein X is an amino acid or trimethylglycine. Methods of making and using the compositions are also provided. The zinc X halide is can be used to deliver zinc salts to block perspiration and provide antibacterial effects.
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公开(公告)号：US09757320B2
公开(公告)日：2017-09-12
申请号：US14652780
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： Zhigang Hao , Ying Yang , Zhiqiang Liu , Xu Guofeng , Paul Joseph Vincenti
CPC classification number: A61K8/58 , A61K8/27 , A61K8/55 , A61K8/676 , A61K33/30 , A61K2800/58 , A61Q11/00
Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
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