公开(公告)号：US11280740B2

公开(公告)日：2022-03-22

申请号：US16968330

申请日：2018-04-06

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs ,  Raghuvir N. Sengupta

IPC: G01N21/65 ,  G01J3/44 ,  G01N21/64 ,  G01N21/552 ,  B82Y15/00

Abstract: A luminescence-enhancement system can include a luminescence-enhancement sensor having a substrate and a group of nanofingers with individual nanofingers that can be flexible and include a support end attached to the substrate, a distal tip positioned distally with respect to the substrate, and a middle portion between the support end and the distal tip. A coating of a metal or metal alloy can be applied to the substrate and the distal tip that is conductively continuous. The middle portion can be devoid of the coating or the coating at the middle portion is conductively discontinuous. A liquid ejector can be present and can include a jetting nozzle to eject a liquid droplet having a volume of 2 pL to 10 μL. The group of nanofingers and the jetting nozzle can be positionable relative to one another for the droplet to be deposited on the group of nanofingers.

公开(公告)号：US11213791B2

公开(公告)日：2022-01-04

申请号：US15763064

申请日：2015-10-22

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Ning Ge ,  Anita Rogacs

IPC: B01D63/00 ,  B01D69/10 ,  B01D39/16 ,  B01D61/38 ,  B01D63/08 ,  B01D67/00 ,  B01L3/00 ,  B01D69/04 ,  B01D69/14

Abstract: A microporous structure includes an array of nano wires and a coating about the nano wires of the array. The coating defines pores between the nano wires.

公开(公告)号：US10983061B2

公开(公告)日：2021-04-20

申请号：US16606429

申请日：2017-10-24

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs ,  Raghuvir N. Sengupta

IPC: B82Y15/00 ,  G01N21/65

Abstract: A surface enhanced luminescence analyte nano pillar stage may include a substrate, an array of closable pillars extending from the substrate and a fluid supply connected to the array of pillars. The fluid supply is to at least partially replenish fluid amongst the pillars of the array that has evaporated to maintain a level of the fluid amongst the pillars of the array below tops of the pillars.

公开(公告)号：US20210018466A1

公开(公告)日：2021-01-21

申请号：US16606013

申请日：2018-04-11

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Viktor Shkolnikov ,  Steven Barcelo

IPC: G01N29/02 ,  G01N29/22 ,  G01N29/50 ,  G01N21/17

Abstract: The present disclosure is drawn to a photoacoustic explosives detector, including a sample chamber, an aerosolizing ejector, a light source, and a pressure differential sensor. The sample chamber can include a photoreaction region, and the aerosolizing ejector can be positioned to eject 3 pL to 10 nL droplets of a liquid sample into the photoreaction region. A light source can be directed to emit focused light through the photoreaction region, and a pressure differential sensor can be positioned with respect to the photoreaction region to sense degradation of the droplets exposed to the focused light.

公开(公告)号：US10648915B2

公开(公告)日：2020-05-12

申请号：US15764327

申请日：2015-11-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ning Ge ,  Steven Barcelo ,  Anita Rogacs ,  Helen A Holder

IPC: G01N21/65 ,  G01N21/64 ,  G01J3/44 ,  B65B31/06 ,  B81C1/00

Abstract: In an example implementation, a substance detection device includes a chamber with chamber walls, a chamber top, and a chamber bottom. A substrate comprises imprinted nanostructures positioned within the chamber, and the substrate is coupled to the chamber walls to form the chamber bottom. An inert gas is sealed within the chamber.

公开(公告)号：US10458918B2

公开(公告)日：2019-10-29

申请号：US15764324

申请日：2015-11-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ning Ge ,  Steven Barcelo ,  Charles M Santori ,  Helen A Holder

IPC: G01N21/03 ,  G01N21/65

Abstract: In an example implementation, a substance detection device includes a substrate having nanoimprinted chamber walls and nanostructures. The chamber walls define a chamber and the nanostructures are positioned within the chamber to react to a substance introduced into the chamber. A two-dimensional (2D) orifice plate is affixed to the chamber walls and forms a top side of the chamber.

公开(公告)号：US20180275066A1

公开(公告)日：2018-09-27

申请号：US15764322

申请日：2015-11-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ning GE ,  Steven Barcelo ,  Anita Rogacs ,  Helen A. Holder

IPC: G01N21/65 ,  G01N27/22 ,  G01N1/44 ,  G01N21/64

Abstract: In an example implementation, a substance detection method includes sensing for fluid in a chamber of a substance detection device. When fluid is sensed in the chamber, the method includes sensing again for fluid in the chamber. When no fluid is sensed in the chamber, the method includes initiating a substance detection process.

公开(公告)号：US09778198B2

公开(公告)日：2017-10-03

申请号：US15247693

申请日：2016-08-25

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

IPC: G01J3/44 ,  G01B11/16 ,  G01N21/00 ,  G01N21/65 ,  B82Y15/00

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01N2201/06113 ,  Y10S977/954

Abstract: An apparatus for performing a sensing application may a substrate having a plurality of nano-fingers positioned to receive the dispensed solution , first and second reservoirs, first and second dispensers to dispense first and second solutions from the first and second reservoirs onto first and second subsets of the plurality of nano-fingers. The plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus may include an illumination source to illuminate the first and second solutions and an analyte introduced around the plurality of nano-fingers, wherein light is to be emitted from the analyte in response to being illuminated. The apparatus may include a detector to detect the light emitted from the analyte.

公开(公告)号：US20250027966A1

公开(公告)日：2025-01-23

申请号：US18713157

申请日：2021-12-15

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Raghuvir N. Sengupta ,  Viktor Shkolnikov ,  Steven Barcelo

IPC: G01N35/10

Abstract: In accordance with the present disclosure, an example non-transitory computer readable medium may store instructions that when executed cause a computing device to dispense, using a first fluid ejector of a microfluidic device, a biologic sample to a region of a substrate, dispense, using a second fluid ejector of the microfluidic device, a reagent to the region of the substrate, and dispense, using a third fluid ejector of the microfluidic device, a metabolic indicator to the region of the substrate, wherein the metabolic indicator provides a visual indication in response to reaction with the biologic sample.

公开(公告)号：US20210252499A1

公开(公告)日：2021-08-19

申请号：US17054675

申请日：2018-10-11

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Fausto D'Apuzzo ,  Trinny Tat ,  Raghuvir N. Sengupta ,  Steven Barcelo ,  Anita Rogacs

IPC: B01L3/02

Abstract: In one example, an apparatus includes a surface-enhanced substrate having a microdot deposited onto a surface thereon via a microfluidic ejector. The microdot includes a predetermined concentration of an analyte.