公开(公告)号：US06429434B1

公开(公告)日：2002-08-06

申请号：US09398497

申请日：1999-09-17

Applicant: Charles C. Watson ,  Stephen D. Miller ,  Ronald Nutt ,  Michael E. Casey ,  James J. Hamill

Inventor： Charles C. Watson ,  Stephen D. Miller ,  Ronald Nutt ,  Michael E. Casey ,  James J. Hamill

IPC: G01T1166

CPC classification number: G01T1/2985 ,  A61B6/037 ,  G01T1/1648 ,  G21K1/02

Abstract: A transmission source serves to detect activity from a radiation source for correcting attenuation in either PET mode or SPECT mode. The transmission source includes a detector dedicated to collecting attenuation data in PET mode. A collimated radiation source and a detector are positioned with respect to a tomography device such that only a selected strip of the imaging detector of the tomograph is illuminated such that events unrelated to the attenuation are eliminated. The transmission source can either be a coincidence transmission source or a singles transmission source and includes a collimator in which is disposed a radiation source. An opening is defined by the collimator for exposing a selected portion of the imaging detectors of the tomograph device. Positioned behind the radiation source, relative to the imaging detectors, is the dedicated attenuation detector. In a dual head tomograph device, one transmission source of the present invention is disposed opposite each bank of imaging detectors. The sources and the associated collimators are positioned to the side of each head at a slight angle relative to the respective head. The sources and detectors are fixed relative to the imaging heads. In order to obtain full coverage of the field of view (FOV) in the same manner as for an emission scan, the heads and sources are rotated about the center of the camera. In SPECT mode, the point source is selected to have sufficiently high energy to shine through the patient and the collimators associated with the imaging detector.

Abstract translation: 传输源用于检测来自辐射源的活动以校正PET模式或SPECT模式中的衰减。 传输源包括专用于在PET模式下收集衰减数据的检测器。 准直辐射源和检测器相对于断层摄影装置定位，使得只有层析成像仪的成像检测器的选定条带被照亮，从而消除与衰减无关的事件。 传输源可以是重合传输源或单个传输源，并且包括准直仪，其中设置有辐射源。 由准直器限定开口以暴露层析成像装置的成像检测器的选定部分。 相对于成像检测器定位在辐射源之后，是专用的衰减检测器。 在双头断层摄影装置中，本发明的一个发射源与每一组成像检测器相对设置。 源和相关联的准直仪相对于相应的头部以相当小的角度定位在每个头部的侧面。 源和检测器相对于成像头是固定的。 为了以与发射扫描相同的方式获得视场（FOV）的全面覆盖，头部和源围绕照相机的中心旋转。 在SPECT模式中，点源被选择为具有足够高的能量以照射通过患者和与成像检测器相关联的准直仪。

公开(公告)号：US10186337B2

公开(公告)日：2019-01-22

申请号：US12887933

申请日：2010-09-22

Applicant: James J. Hamill ,  Stefan B. Siegel ,  Charles Russell Buchanan

Inventor： James J. Hamill ,  Stefan B. Siegel ,  Charles Russell Buchanan

IPC: G21G1/06 ,  G21G1/00

Abstract: A method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source. More specifically, a solution includes a particular isotope. The neutron source is completely surrounded by the solution. The solution is exposed to the neutrons. Generated radioisotopes are extracted from the solution.

公开(公告)号：US09456791B2

公开(公告)日：2016-10-04

申请号：US12558159

申请日：2009-09-11

Applicant: James J. Hamill ,  Carl Eric Arnsdorff

Inventor： James J. Hamill ,  Carl Eric Arnsdorff

IPC: A61G15/00 ,  A61B6/03 ,  A61B6/04 ,  A61B5/103 ,  A61B6/00

CPC classification number: A61B6/037 ,  A61B5/103 ,  A61B6/0421 ,  A61B6/482

Abstract: A constraint having a main body and at least one coupler. The main body can be substantially arcuate in shape and can be configured to constrain a patient. The at least one coupler can couple the main body to a bed or treatment pallet. The constraint can be sized to restrict a patient within a computerized tomography (CT) scan field of view.

Abstract translation: 具有主体和至少一个耦合器的约束。 主体可以是基本上弓形的形状，并且可以构造成约束患者。 所述至少一个联接器可以将主体连接到床或处理托盘。 该约束的大小可以限制在计算机断层摄影（CT）扫描视野内的患者。

公开(公告)号：US07769217B2

公开(公告)日：2010-08-03

申请号：US11714406

申请日：2007-03-06

Applicant: James J. Hamill

Inventor： James J. Hamill

IPC: G06K9/00

CPC classification number: G06T11/006 ,  G06T2211/424

Abstract: A method for performing accurate iterative reconstruction of three dimensional image data sets based on Approximate Discrete Radon Transformation (ADRT) using two dimensional linograms for each of a plurality of defined planes tilted from the (x, y, 0) plane by a tilt angle and orientation angle. Image data is arranged with respect to the defined tilted planes ADRT and its inverse are implemented to provide exactly matched forward and backward projectors suitable for the Maximum-Likelihood Expectation-Maximization (ML-EM) reconstruction in PET. An EM reconstruction algorithm is accomplished by initializing an estimation image.

Abstract translation: 一种用于基于近似离散氡变换（ADRT）对三维图像数据集进行精确迭代重建的方法，所述方法使用用于从（x，y，0）平面倾斜倾斜角度的多个限定平面中的每一个定义的平面使用二维立体图， 取向角度。 图像数据相对于定义的倾斜平面ADRT布置，并且其反向被实现以提供适合于PET中的最大似然期望最大化（ML-EM）重建的精确匹配的前向和后向投影仪。 通过初始化估计图像来实现EM重建算法。

公开(公告)号：US07483518B2

公开(公告)日：2009-01-27

申请号：US11519410

申请日：2006-09-12

Applicant: James J. Hamill

Inventor： James J. Hamill

IPC: H01J35/10 ,  H01J35/00 ,  G21K3/00

CPC classification number: H01J35/18 ,  G21K1/10 ,  H01J35/305 ,  H01J2235/183

Abstract: An X-ray imaging apparatus is disclosed. The apparatus includes a radiator housing, an X-ray tube, a source of X-rays and at least one filtration material disposed on the X-ray tube. The X-ray tube is rotatable about a longitudinal axis and is disposed at least partially within the radiator housing. The source of X-rays emits at least one X-ray beam at least partially through the X-ray tube. The X-ray beam exits the X-ray tube at an annular X-ray window. The filtration material at least partially covers a portion of the annular X-ray window. Rotation of the X-ray tube causes the X-ray beam to pass through a plurality of locations in the annular X-ray window and at least a portion of the X-ray beam is filtered by the filtration material.

Abstract translation: 公开了一种X射线成像装置。 该装置包括散热器壳体，X射线管，X射线源和设置在X射线管上的至少一个过滤材料。 X射线管可以围绕纵向轴线旋转并且至少部分地设置在散热器壳体内。 X射线源至少部分地通过X射线管发射至少一个X射线束。 X射线束以环形X射线窗口离开X射线管。 过滤材料至少部分地覆盖环形X射线窗口的一部分。 X射线管的旋转导致X射线束穿过环形X射线窗口中的多个位置，X射线束的至少一部分被过滤材料过滤。

公开(公告)号：US20080063145A1

公开(公告)日：2008-03-13

申请号：US11519410

申请日：2006-09-12

Applicant: James J. Hamill

Inventor： James J. Hamill

IPC: H01J35/10

CPC classification number: H01J35/18 ,  G21K1/10 ,  H01J35/305 ,  H01J2235/183

Abstract: An X-ray imaging apparatus is disclosed. The apparatus includes a radiator housing, an X-ray tube, a source of X-rays and at least one filtration material disposed on the X-ray tube. The X-ray tube is rotatable about a longitudinal axis and is disposed at least partially within the radiator housing. The source of X-rays emits at least one X-ray beam at least partially through the X-ray tube. The X-ray beam exits the X-ray tube at an annular X-ray window. The filtration material at least partially covers a portion of the annular X-ray window. Rotation of the X-ray tube causes the X-ray beam to pass through a plurality of locations in the annular X-ray window and at least a portion of the X-ray beam is filtered by the filtration material.

Abstract translation: 公开了一种X射线成像装置。 该装置包括散热器壳体，X射线管，X射线源和设置在X射线管上的至少一个过滤材料。 X射线管可以围绕纵向轴线旋转并且至少部分地设置在散热器壳体内。 X射线源至少部分地通过X射线管发射至少一个X射线束。 X射线束以环形X射线窗口离开X射线管。 过滤材料至少部分地覆盖环形X射线窗口的一部分。 X射线管的旋转导致X射线束穿过环形X射线窗口中的多个位置，X射线束的至少一部分被过滤材料过滤。

公开(公告)号：US09579070B2

公开(公告)日：2017-02-28

申请号：US13248089

申请日：2011-09-29

Applicant: James J. Hamill ,  Ludovic Le Meunier

Inventor： James J. Hamill ,  Ludovic Le Meunier

IPC: A61B5/00 ,  A61B6/00 ,  A61B5/113 ,  A61B6/03 ,  G01R33/48 ,  G01R33/567

CPC classification number: A61B5/7292 ,  A61B5/1135 ,  A61B6/037 ,  A61B6/541 ,  G01R33/481 ,  G01R33/5676

Abstract: Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.

Abstract translation: 提供方法和计算机可读介质以获得最佳门控的医学图像。 例如，在一个实施例中，提供了以列表模式获取医学图像的方法。 该方法还获取呼吸相关信号S（t）。 此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。 医学图像与呼吸相关信号S（t）同步。 同步的图像和信号用于创建最佳门控的医学图像。 在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。 在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

公开(公告)号：US20130085375A1

公开(公告)日：2013-04-04

申请号：US13248089

申请日：2011-09-29

Applicant: James J. Hamill ,  Ludovic Le Meunier

Inventor： James J. Hamill ,  Ludovic Le Meunier

IPC: A61B5/055 ,  A61B5/05

CPC classification number: A61B5/7292 ,  A61B5/1135 ,  A61B6/037 ,  A61B6/541 ,  G01R33/481 ,  G01R33/5676

Abstract: Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.

Abstract translation: 提供方法和计算机可读介质以获得最佳门控的医学图像。 例如，在一个实施例中，提供了以列表模式获取医学图像的方法。 该方法还获取呼吸相关信号S（t）。 此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。 医学图像与呼吸相关信号S（t）同步。 同步的图像和信号用于创建最佳门控的医学图像。 在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。 在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

公开(公告)号：US08060177B2

公开(公告)日：2011-11-15

申请号：US11714405

申请日：2007-03-06

Applicant: James J. Hamill

Inventor： James J. Hamill

IPC: A61B5/05

CPC classification number: A61B6/032 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/541 ,  G01T1/1615

Abstract: A method for combined computed tomography (CT) imaging and positron emission tomography (PET) imaging uses respiration-gated CT imaging in which the optimal criteria for CT scan gating are determined after the PET scan has been performed. After acquisition of first CT scan image data and PET scan image data with strain gauge levels being recorded, optimal gating criteria are calculated based on the strain gauge levels, and a second CT scan is then performed with triggering in accordance with the optimal gating criteria.

Abstract translation: CT扫描成像和正电子发射断层扫描（PET）成像的方法是使用呼吸门控CT成像，其中在执行PET扫描之后确定CT扫描门控的最佳标准。 在记录了应变仪电平的第一CT扫描图像数据和PET扫描图像数据的采集之后，根据应变计电平计算最佳选通标准，然后根据最佳选通标准触发进行第二次CT扫描。

公开(公告)号：US20090076379A1

公开(公告)日：2009-03-19

申请号：US12125329

申请日：2008-05-22

Applicant: James J. Hamill ,  Gunther Platsch ,  Michael E. Casey

Inventor： James J. Hamill ,  Gunther Platsch ,  Michael E. Casey

IPC: A61B8/14 ,  A61B5/05

CPC classification number: A61B8/08 ,  A61B5/7285 ,  A61B6/032 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/4245 ,  A61B8/5238 ,  A61B8/543 ,  G01T1/1603

Abstract: A medical imaging device has an emission tomograph, at least one ultrasonic (US) probe for providing images giving real-time information about the location of the internal organs of a subject, a tracking system for spatially locating the at least one ultrasonic probe in relation to the medical imaging device, and an image processing unit in which the location information obtained by the ultrasonic probe is used for attenuation correction of image information obtained by the emission tomograph.

Abstract translation: 一种医疗成像装置具有发射断层摄影机，至少一个超声波（US）探头，用于提供给出关于被检体的内部器官的位置的实时信息的图像，用于相对于空间定位至少一个超声波探头的跟踪系统 以及图像处理单元，其中由超声波探头获得的位置信息用于由发射断层摄影机获得的图像信息的衰减校正。