公开(公告)号：US20110257037A1

公开(公告)日：2011-10-20

申请号：US13168298

申请日：2011-06-24

Applicant: Beom-seok LEE ,  Jeong-gun Lee ,  Jong-myeon Park ,  Yoon-kyoung Cho

Inventor： Beom-seok LEE ,  Jeong-gun Lee ,  Jong-myeon Park ,  Yoon-kyoung Cho

IPC: C40B40/00 ,  C40B40/10 ,  C40B40/02 ,  C40B40/06

CPC classification number: B01L3/502738 ,  B01L3/502707 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/04 ,  B01L2300/0636 ,  B01L2300/0806 ,  B01L2400/0409 ,  B01L2400/0677 ,  Y10T436/15

Abstract: Disclosed is a microfluidic device including a microfluidic structure formed in a platform in which various examinations, such as an immune serum examination, can be automatically performed using the biomolecule microarray chip. The biomolecule microarray chip-type microfluidic device using a biomolecule microarray chip comprises: a platform which is rotatable; a microfluidic structure disposed in the platform, comprising: a plurality of chambers; a plurality of channels connecting the chambers each other; and a plurality of valves controlling flow of fluids through the channels, wherein the microfluidic structure controls flow of a fluid sample using rotation of the platform and the valves; and a biomolecule microarray chip mounted in the platform such that biomolecule capture probes bound to the biomolecule microarray chip contact the fluid sample in the microfluidic structure.

Abstract translation: 公开了一种微流体装置，其包括在平台中形成的微流体结构，其中可以使用生物分子微阵列芯片自动执行各种检查，例如免疫血清检查。 使用生物分子微阵列芯片的生物分子微阵列芯片型微流器件包括：可旋转的平台; 设置在平台中的微流体结构，包括：多个室; 连接所述室的多个通道; 以及多个阀，其控制通过所述通道的流体流动，其中所述微流体结构通过所述平台和所述阀的旋转来控制流体样品的流动; 以及安装在平台中的生物分子微阵列芯片，使得与生物分子微阵列芯片结合的生物分子捕获探针与微流体结构中的流体样品接触。

公开(公告)号：US20110015094A1

公开(公告)日：2011-01-20

申请号：US12888927

申请日：2010-09-23

Applicant: Beom-seok LEE ,  Jeong-gun LEE ,  Hye-jung CHO ,  In-seok KANG ,  Jae-suk MOON ,  Jin-seok HONG

Inventor： Beom-seok LEE ,  Jeong-gun LEE ,  Hye-jung CHO ,  In-seok KANG ,  Jae-suk MOON ,  Jin-seok HONG

IPC: C40B40/02 ,  C40B40/06 ,  C40B40/10 ,  C40B50/18

CPC classification number: B01L3/0262 ,  B01J19/0046 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01J2219/00527 ,  B01J2219/00605 ,  B01J2219/00689 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/0074 ,  B01J2219/00743 ,  B01L2300/0819 ,  B01L2300/0838 ,  B01L2400/027 ,  Y10T436/11 ,  Y10T436/118339 ,  Y10T436/119163 ,  Y10T436/25 ,  Y10T436/2575

Abstract: Disclosed is an apparatus and method for ejecting droplets using charge concentration and liquid bridge breakup. The droplet ejection apparatus includes a reservoir storing a liquid; a capillary nozzle having a lower end submerged in the liquid stored in the reservoir and an upper end exposed outside the surface of the liquid, the capillary nozzle transferring the liquid to the upper end using capillary force; a potentiostat for applying a voltage to the liquid; a substrate mount on which a substrate is disposed to face the upper end of the capillary nozzle; and a distance adjusting unit for reciprocatingly moving the substrate between first and second positions with respect to the capillary nozzle, wherein the first position denotes a position where a distance between the upper end of the capillary nozzle and the surface of the substrate is less than a effective distance.

Abstract translation: 公开了一种使用电荷浓度和液桥分解喷射液滴的装置和方法。 液滴喷射装置包括储存液体的储液器; 毛细喷嘴，其下端浸没在存储在储存器中的液体中，上端暴露在液体表面之外，毛细喷嘴使用毛细管力将液体传送到上端; 用于向液体施加电压的恒电位仪; 基板安装件，基板设置在其上面对毛细管喷嘴的上端; 以及距离调节单元，用于使所述基板相对于所述毛细管喷嘴在第一位置和所述第二位置之间往复移动，其中所述第一位置表示所述毛细管喷嘴的上端与所述基板的表面之间的距离小于 有效距离。

公开(公告)号：US20080269077A1

公开(公告)日：2008-10-30

申请号：US12108823

申请日：2008-04-24

Applicant: Beom-seok LEE ,  Yoon-kyoung CHO ,  Jong-myeon PARK ,  Jung-nam LEE

Inventor： Beom-seok LEE ,  Yoon-kyoung CHO ,  Jong-myeon PARK ,  Jung-nam LEE

IPC: C40B60/00

CPC classification number: B01L3/502738 ,  B01L3/50273 ,  B01L2200/0684 ,  B01L2300/0806 ,  B01L2300/0861 ,  B01L2400/0409 ,  B01L2400/06 ,  B01L2400/0677 ,  G01N21/07 ,  Y10T436/111666 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: Provided are a centrifugal microfluidic device having a sample distribution structure and a centrifugal microfluidic system including the centrifugal microfluidic device. The centrifugal microfluidic device includes: a rotatable platform; a sample chamber which is disposed in the rotatable platform and houses a fluid sample; a distribution channel connected to an outlet of the sample chamber; a valve which is disposed in the outlet of the sample chamber; a plurality of non-vented reaction chambers which are disposed in the rotatable platform outside of the distribution channel in the radial direction; and a plurality of inlet channels connecting the distribution channel with the reaction chambers.

Abstract translation: 提供了具有样品分布结构和包括离心微流体装置的离心微流体系统的离心微流体装置。 离心微流体装置包括：可旋转平台; 样品室，其设置在所述可旋转平台中并容纳流体样品; 连接到样品室的出口的分配通道; 设置在样品室的出口的阀; 多个非排气反应室，其在径向上设置在分配通道外部的可旋转平台内; 以及将分配通道与反应室连接的多个入口通道。

公开(公告)号：US20080017736A1

公开(公告)日：2008-01-24

申请号：US11781714

申请日：2007-07-23

Applicant: Beom-seok LEE ,  Jeong-gun LEE ,  Hye-jung CHO

Inventor： Beom-seok LEE ,  Jeong-gun LEE ,  Hye-jung CHO

IPC: B05B5/00

CPC classification number: B05B5/0255 ,  B01J2219/00367 ,  B01J2219/00369 ,  B01J2219/00371 ,  B01L3/0268 ,  B01L2300/0838 ,  B01L2300/161 ,  B01L2400/027 ,  B01L2400/0406 ,  B01L2400/0487 ,  B05B1/14 ,  B05B5/0533 ,  B41J2/06

Abstract: Provided is a droplet dispensing device having a nonconductive capillary nozzle. The droplet dispensing device comprises: a nonconductive capillary nozzle disposed in a downward position; a pump connected with the nonconductive capillary nozzle through a hermetically sealed fluid tube and generating a negative pressure to decrease the influence of gravity on a solution within the nonconductive capillary nozzle and the fluid tube; and an open circuit voltage supplier applying a voltage to the solution. The droplet dispensing device supplies the solution by capillary force to regularly maintain the shape of a droplet surface in the tip of the nonconductive capillary nozzle without using a separate driving device.

Abstract translation: 提供了具有非导电毛细管喷嘴的液滴分配装置。 液滴分配装置包括：设置在向下位置的非导电毛细管喷嘴; 泵，其通过气密密封的流体管与非导电毛细管喷嘴连接并产生负压，以减少重力对非导电毛细管喷嘴和流体管内的溶液的影响; 以及向该溶液施加电压的开路电压供给器。 液滴分配装置通过毛细管力提供溶液以在不使用单独的驱动装置的情况下规定地保持非导电毛细管喷嘴的尖端中的液滴表面的形状。

公开(公告)号：US20120028852A1

公开(公告)日：2012-02-02

申请号：US13269411

申请日：2011-10-07

Applicant: Beom-seok LEE ,  Yoon-kyoung Cho ,  Jong-myeon Park ,  Jeong-gun Lee

Inventor： Beom-seok LEE ,  Yoon-kyoung Cho ,  Jong-myeon Park ,  Jeong-gun Lee

IPC: C40B60/12

CPC classification number: B01L3/502738 ,  B01L3/502723 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2300/0636 ,  B01L2300/0803 ,  B01L2300/0806 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/084 ,  B01L2400/086 ,  F16K99/0001 ,  F16K99/0019 ,  F16K99/0032 ,  F16K99/004 ,  F16K99/0061 ,  F16K2099/0084 ,  G01N35/00069

Abstract: Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit.

公开(公告)号：US20110232832A1

公开(公告)日：2011-09-29

申请号：US13157535

申请日：2011-06-10

Applicant: Jong-myeon PARK ,  Yoon-kyoung CHO ,  Beom-seok LEE ,  Jeong-gun LEE

Inventor： Jong-myeon PARK ,  Yoon-kyoung CHO ,  Beom-seok LEE ,  Jeong-gun LEE

IPC: B21K1/20 ,  H05B6/10 ,  B32B37/00

CPC classification number: F16K99/0001 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0084 ,  Y10T29/49412 ,  Y10T137/2191 ,  Y10T137/2196

Abstract: Provided is a microfluidic valve, a method of manufacturing the microfluidic valve, and a microfluidic device that employs the microfluidic valve. The microfluidic valve includes a platform that includes two substrates combined facing each other; a channel having a first depth allowing a fluid to flow between the two substrates; a valve gap that is disposed on at least a region of the channel and has a second depth which is smaller than the first depth; and a valve plug that is disposed to fill the valve gap and is formed of a valve material made by mixing a phase change material, which is solid at room temperature, with a plurality of exothermic particles that emit an amount of heat sufficient to melt the phase change material by absorbing electromagnetic waves.

Abstract translation: 本发明提供一种微流体阀，微流体阀的制造方法和采用该微流体阀的微流体装置。 该微流体阀包括一个平台，该平台包括彼此相结合的两个基板; 具有允许流体在两个基板之间流动的第一深度的通道; 阀间隙，其设置在所述通道的至少一个区域上，并且具有小于所述第一深度的第二深度; 以及阀塞，其设置成填充阀间隙，并且由阀室材料形成，所述阀门材料是通过将在室温下为固体的相变材料与多个放出足以熔化的 相变材料通过吸收电磁波。

公开(公告)号：US20090307544A1

公开(公告)日：2009-12-10

申请号：US12331701

申请日：2008-12-10

Applicant: Bum-keun KIM ,  Kyung-young KIM ,  Jung-hwan OH ,  Beom-seok LEE

Inventor： Bum-keun KIM ,  Kyung-young KIM ,  Jung-hwan OH ,  Beom-seok LEE

IPC: G11C29/04 ,  G06F11/22

CPC classification number: G11C29/56 ,  G11C29/56004

Abstract: A memory test device, including a universal register to conduct an operation by a predetermined universal command language; an extension register having a larger capacity than the universal register and to conduct an operation by a predetermined extension command language; and a controller to write a predetermined test pattern in an external memory using the extension command language, to read the test pattern written in the memory, to determine the identity of the written test pattern and the read test pattern, and to determine a presence of an error in the memory using the universal command language.

Abstract translation: 一种存储器测试装置，包括通用寄存器，用于通过预定的通用命令语言进行操作; 扩展寄存器，其具有比通用寄存器更大的容量并且以预定的扩展命令语言进行操作; 以及使用扩展命令语言在外部存储器中写入预定测试模式的控制器，读取写入存储器中的测试模式，以确定写入的测试模式和读取的测试模式的身份，并且确定存在 使用通用命令语言的内存中的错误。

公开(公告)号：US20080187474A1

公开(公告)日：2008-08-07

申请号：US12027290

申请日：2008-02-07

Applicant: Jong-myeon PARK ,  Beom-seok LEE

Inventor： Jong-myeon PARK ,  Beom-seok LEE

IPC: B01J19/00 ,  C09K3/10 ,  H01F1/00

CPC classification number: F16K99/0019 ,  B01L3/502738 ,  B01L2300/1861 ,  B01L2400/0677 ,  F16K99/0001 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0069 ,  F16K2099/0084 ,  Y10T137/2196

Abstract: Provided are a valve filler and a valve unit including the valve filler. The valve filler includes: a phase transition material; and a heating fluid comprising a carrier oil and a plurality of micro heating particles suspended in the carrier oil, the heating fluid being mixed with the phase transition material, wherein, when external energy is supplied, the micro heating particles receive the external energy and generate heat to melt the phase transition material into a fluid state, and when no external energy is supplied, the phase transition material hardens into a solid state.

Abstract translation: 提供了一种阀填料和包括阀填料的阀单元。 阀填料包括：相变材料; 以及加热流体，其包含载体油和悬浮在载体油中的多个微加热颗粒，所述加热流体与所述相变材料混合，其中，当供应外部能量时，所述微加热颗粒接收外部能量并产生 将相变材料熔化成流体状态的热量，当没有外部能量供给时，相变材料变硬。

公开(公告)号：US20080058192A1

公开(公告)日：2008-03-06

申请号：US11847623

申请日：2007-08-30

Applicant: Yoon-kyoung CHO ,  Jeong-gun LEE ,  Beom-seok LEE ,  Jong-myeon PARK

Inventor： Yoon-kyoung CHO ,  Jeong-gun LEE ,  Beom-seok LEE ,  Jong-myeon PARK

IPC: B04B15/02 ,  B01D21/26 ,  B04B13/00

CPC classification number: F16K99/003 ,  B01L3/502738 ,  B01L2300/0806 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2400/0409 ,  B01L2400/0677 ,  F16K99/0001 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0084

Abstract: A centrifugal force based microfluidic device including a thermal activation unit, a microfluidic system including the same, and a method of operating the microfluidic system are provided. The thermal activation unit accompanies a temperature change in order to carry out its functions and having heat generation particles that absorb electromagnetic waves and generate heat in the activation unit therein.

Abstract translation: 提供了一种基于离心力的微流体装置，其包括热激活单元，包括该激活单元的微流体系统以及操作微流体系统的方法。 热激活单元伴随着温度变化，以便执行其功能并具有吸收电磁波并在其中的激活单元中产生热量的发热颗粒。

公开(公告)号：US20080035579A1

公开(公告)日：2008-02-14

申请号：US11837038

申请日：2007-08-10

Applicant: Jeong-gun LEE ,  Yoon-kyoung CHO ,  Beom-seok LEE ,  Jong-myeon PARK

Inventor： Jeong-gun LEE ,  Yoon-kyoung CHO ,  Beom-seok LEE ,  Jong-myeon PARK

IPC: B01D43/00 ,  B04B5/10

CPC classification number: G01N35/00069 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2300/0803 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0887 ,  B01L2400/0409 ,  B01L2400/043 ,  G01N35/0098 ,  Y10T436/25375

Abstract: A centrifugal micro fluidic system and a centrifugal magnetic position control device used in the centrifugal micro fluidic system for controlling the position of magnetic beads are provided. The centrifugal micro fluidic system comprising, a rotatable platform; a micro fluidic structure which is disposed in the platform; and a plurality of objects which include functional groups on surfaces thereof so as to capture a target material from the fluid and carry the target material while being suspended in and separated from the fluid in the micro fluidic structure, wherein the movements of the objects are controlled by a force affecting the objects differently compared to the force's effect on the fluid. When the objects are made of a magnetic material, the force may be a magnetic force applied by the centrifugal magnetic position control device.

Abstract translation: 提供了一种用于离心微流体系统中用于控制磁珠位置的离心微流体系统和离心磁位置控制装置。 离心微流体系统包括：可旋转平台; 设置在平台中的微流体结构; 以及包括在其表面上的官能团的多个物体，以便从流体中捕获目标材料并且在悬浮在微流体结构中的流体中并与微流体结构中的流体分离时携带目标材料，其中物体的移动被控制 通过影响对象的力与力对液体的影响不同。 当物体由磁性材料制成时，力可以是由离心磁位置控制装置施加的磁力。