公开(公告)号：US5334142A

公开(公告)日：1994-08-02

申请号：US756693

申请日：1991-09-09

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61B17/12 ,  A61B19/02 ,  A61F2/958 ,  A61M1/10 ,  A61M25/00 ,  A61M31/00

CPC classification number: A61M25/1002 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B50/33 ,  A61M1/1072 ,  A61M25/002 ,  A61B17/12022 ,  A61M2025/0002 ,  A61M2025/1059 ,  A61M2025/1072 ,  A61M2202/0476 ,  A61M2209/06 ,  A61M25/10

Abstract: A method and apparatus for carrying out aortic occlusion along with oxygen carrying fluid infusion for use during CPR including the use of a specially constructed balloon catheter which, when inflated, occludes the aorta such that an oxygenated fluid infused through the catheter will be restricted to that part of the aorta above the balloon occlusion. The inner lumen of the catheter must have a diameter of at least two millimeters.

Abstract translation: 一种用于在CPR期间进行主动脉闭塞以及携带液体输注的氧气的方法和装置，包括使用特别构造的气囊导管，当气囊膨胀时，气囊导管封闭主动脉，使得通过导管注入的充氧液体将被限制在 气囊闭塞以上主动脉的一部分。 导管的内腔必须具有至少两毫米的直径。

公开(公告)号：US20180021216A1

公开(公告)日：2018-01-25

申请号：US15657078

申请日：2017-07-21

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61H31/00

CPC classification number: A61H31/006 ,  A61H31/008 ,  A61H2230/045 ,  A61H2230/08

Abstract: A method to increase the overall hemodynamic efficacy of cardiopulmonary resuscitation (CPR) by alternating between chest compression-decompression cycles optimized to either cardiac output or venous return. The phases of cardiac output and venous return enhancement may themselves by adjusted in their duration and character. The method may enhance mechanical and manual techniques delivered to the anterior or circumferential chest, and be synchronized to adjunctive techniques such as airway, ventilatory or abdominal therapies.

公开(公告)号：US09719842B2

公开(公告)日：2017-08-01

申请号：US14473960

申请日：2014-08-29

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: G01N33/48 ,  G01G19/44 ,  A61B5/00 ,  A61B8/08 ,  G06F19/00 ,  G06G7/58 ,  G06F19/24 ,  A61B5/0205

CPC classification number: G01G19/44 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/0205 ,  A61B5/7264 ,  A61B5/7275 ,  A61B8/08 ,  G06F19/00 ,  G06F19/24 ,  G16H50/20 ,  G16H50/30

Abstract: A method for diagnosing or predicting the risk of shock, the method incorporating an algorithmic combination of optical, electromagnetic, and other sensors, along with their anatomic and temporal patterns. A method for developing the algorithms through iterative optimization using machine learning.

公开(公告)号：US20150250643A1

公开(公告)日：2015-09-10

申请号：US14642259

申请日：2015-03-09

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61F7/00

CPC classification number: A61F7/0085 ,  A61F7/02 ,  A61F2007/0054 ,  A61F2007/0094 ,  A61F2007/0095

Abstract: A method for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.

Abstract translation: 利用提供受控低体温，正常体温或热疗的装置的传热参数或能量消耗来检测患者内源性设定点温度的变化或不存在变化的方法; 这在外源诱导的靶温度管理中是不可用的。 特定的实施方案将允许在经历靶向温度管理的患者中检测发烧。

公开(公告)号：US20150011844A1

公开(公告)日：2015-01-08

申请号：US14473960

申请日：2014-08-29

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61B5/02 ,  A61B5/00 ,  A61B8/08 ,  G01G19/44 ,  A61B5/1455 ,  A61B5/0402 ,  A61B5/029 ,  A61B5/026 ,  A61B5/0265 ,  A61B5/0205 ,  A61B5/107

CPC classification number: G01G19/44 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/0205 ,  A61B5/7264 ,  A61B5/7275 ,  A61B8/08 ,  G06F19/00 ,  G06F19/24 ,  G16H50/20 ,  G16H50/30

Abstract: A method for diagnosing or predicting the risk of shock, the method incorporating an algorithmic combination of optical, electromagnetic, and other sensors, along with their anatomic and temporal patterns. A method for developing the algorithms through iterative optimization using machine learning.

Abstract translation: 一种用于诊断或预测冲击风险的方法，该方法结合了光学，电磁和其他传感器的算法组合，以及它们的解剖和时间模式。 通过使用机器学习的迭代优化开发算法的方法。

公开(公告)号：US20130337445A1

公开(公告)日：2013-12-19

申请号：US13921613

申请日：2013-06-19

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: G01N33/50

CPC classification number: G01N33/50 ,  G01N33/84

Abstract: A method and apparatus for the discovery, development and clinical application of multiplex synthetic assays based on patterns of free radicals, indicators of oxidative or nitrosative stress, or indicators of the redox state of biologic fluids and tissue specimens. These individual measurements are combined into an optimized clinical biomarker using known well-known mathematical, machine learning techniques.

Abstract translation: 用于基于自由基模式，氧化或亚硝化应激指标或生物流体和组织标本的氧化还原状态的指标的多重合成测定的发现，开发和临床应用的方法和装置。 使用已知的数学，机器学习技术将这些单独的测量结合到优化的临床生物标志物中。

公开(公告)号：US07645247B2

公开(公告)日：2010-01-12

申请号：US10973775

申请日：2004-10-25

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61H31/00

CPC classification number: A61H31/005 ,  A61H31/006 ,  A61H31/007 ,  A61H2031/001 ,  A61H2201/5007 ,  A61H2201/5048 ,  A61H2201/5058 ,  A61H2230/04 ,  A61M16/00 ,  A61M16/0051 ,  A61M16/024 ,  A61M2205/332 ,  Y10S601/09

Abstract: In one embodiment, a method for improving the cardiac output of a patient who is suffering from pulseless electrical activity or shock and yet still displays some myocardial wall motion comprises sensing myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase. In such cases, a compressive force is repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion. Also incorporated may be a logic circuit capable of utilizing multiple sensing modalities and optimizing the synchronization pattern between multiple phasic therapeutic modalities and myocardial residual mechanical function.

Abstract translation: 在一个实施例中，用于改善患有无脉动电活动或休克但仍然显示某些心肌壁运动的患者的心输出量的方法包括感测心肌活动以确定具有收缩或弹出的剩余左心室泵功能的存在 相和填充或松弛阶段。 在这种情况下，基于所感测到的心肌活动，将压缩力重复施加到胸部，使得在至少一些喷射阶段期间施加压缩力，并且在至少一些松弛阶段期间停止压缩力，以允许残留的心脏填充 ，从而增强心输出量和器官灌注。 还可并入的是可以利用多个感测模式并优化多阶段性治疗方式与心肌残留机械功能之间的同步模式的逻辑电路。

公开(公告)号：US20240188884A1

公开(公告)日：2024-06-13

申请号：US18581278

申请日：2024-02-19

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61B5/00 ,  A61B5/08 ,  A61B5/113 ,  A61H9/00 ,  A61H31/00 ,  A61H31/02

CPC classification number: A61B5/4836 ,  A61B5/08 ,  A61B5/1135 ,  A61H9/0078 ,  A61H2031/002 ,  A61H31/02 ,  A61H2201/0103 ,  A61H2201/1238 ,  A61H2201/5087 ,  A61H2230/405 ,  A61H2230/655

Abstract: A device and method for treating chest wall injuries, including thoracic surgeries, rib fractures, flail chest injuries, or surgical incisions so as to lessen pain experienced by patients. The device and method can include creating a localized airtight compartment external to the chest wall and fully covering the area of injury, varying the pressure within the compartment, and providing dynamic real-time counter forces that act reciprocal to the intrathoracic pressure changes that occur during ventilation. In a preferred embodiment, the apparatus has the capability of sensing the patient's chest wall motion created by ventilation, a pressure control component capable of varying the pressure within the airtight compartment such that it opposes pressure changes within the chest. The pattern of positive and negative pressures may be adjusted based on the patient's subjective sense of their pain.

公开(公告)号：US11903726B2

公开(公告)日：2024-02-20

申请号：US17532992

申请日：2021-11-22

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61B5/00 ,  A61B5/05 ,  A61B5/113 ,  A61B5/08 ,  A61H9/00 ,  A61H31/02 ,  A61H31/00

CPC classification number: A61B5/4836 ,  A61B5/08 ,  A61B5/1135 ,  A61H9/0078 ,  A61H31/02 ,  A61H2031/002 ,  A61H2201/0103 ,  A61H2201/1238 ,  A61H2201/5087 ,  A61H2230/405 ,  A61H2230/655

Abstract: A device for treating chest wall injuries, including rib fractures, flail chest injuries or surgical incisions is described herein. The device includes a localized airtight compartment external to the chest wall and fully covering the area of injury, and is capable of varying the pressure within the compartment, and providing dynamic real-time counter forces that act reciprocal to the intrathoracic pressure changes that occur during ventilation. In a preferred embodiment, the device has the capability of sensing the patient's chest wall motion created by ventilation, and includes a pressure control component capable of varying the pressure within the airtight compartment such that it opposes pressure changes within the chest. The apparatus would be particularly useful in preventing the paradoxical movement of flail chest injuries. The device would also lessen pain experienced by patients with thoracic injuries such as rib fractures and post operative suffering.

公开(公告)号：US10772793B2

公开(公告)日：2020-09-15

申请号：US15180964

申请日：2016-06-13

Applicant: Norman A. Paradis

Inventor： Norman A. Paradis

IPC: A61H31/00 ,  A61H9/00

Abstract: The present invention is a method for improving hemodynamics and clinical outcome of patients suffering cardiac arrest and other low-flow states by combination of circumferential constriction and anteroposterior compression decompression of the chest cardiopulmonary resuscitation. Anteroposterior compression decompression may be provided by a piston mechanism attached to a gantry above the patient. Circumferential constriction may be achieved by inflation of pneumatic bladders or shortening of a band. The on-off sequence and relative force of circumferential constriction and anteroposterior compression decompression may be adjusted so as to improve efficacy.