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    Gradient structures interfacing microfluidics and nanofluidics, methods for fabrication and uses thereof
    11.
    发明授权
    Gradient structures interfacing microfluidics and nanofluidics, methods for fabrication and uses thereof 有权

    公开(公告)号：US10551319B2

    公开(公告)日：2020-02-04

    申请号：US15664196

    申请日：2017-07-31

    Applicant: Princeton University

    Inventor： Han Cao ,  Jonas O. Tegenfeldt ,  Stephen Chou ,  Robert H. Austin

    IPC: B01L3/00 ,  G01N21/00 ,  G01N33/00 ,  G01N21/64 ,  B81C1/00 ,  B82Y30/00 ,  G01N33/487 ,  G03F7/20

    Abstract: A fluidic chip includes at least one nanochannel array, the nanochannel array including a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; a gradient interface area having a gradual elevation of height linking the microfluidic area and the nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area. In another embodiment, a fluidic chip includes at least one nanochannel array, the nanochannel array includes a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; and a gradient interface area linking the microfluidic area and the nanofluidic area, where the gradient interface area comprises a plurality of gradient structures, and the lateral spacing distance between said gradient structures decreases towards said nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area.

    GRADIENT STRUCTURES INTERFACING MICROFLUIDICS AND NANOFLUIDICS, METHODS FOR FABRICATION AND USES THEREOF
    12.
    发明申请
    GRADIENT STRUCTURES INTERFACING MICROFLUIDICS AND NANOFLUIDICS, METHODS FOR FABRICATION AND USES THEREOF 审中-公开

    公开(公告)号：US20170328835A1

    公开(公告)日：2017-11-16

    申请号：US15664196

    申请日：2017-07-31

    Applicant: Princeton University

    Inventor： Han Cao ,  Jonas O. Tegenfeldt ,  Stephen Chou ,  Robert H. Austin

    IPC: G01N21/64 ,  G01N33/487 ,  B01L3/00 ,  B81C1/00 ,  B82Y30/00 ,  G03F7/20

    Abstract: A fluidic chip includes at least one nanochannel array, the nanochannel array including a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; a gradient interface area having a gradual elevation of height linking the microfluidic area and the nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area. In another embodiment, a fluidic chip includes at least one nanochannel array, the nanochannel array includes a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; and a gradient interface area linking the microfluidic area and the nanofluidic area, where the gradient interface area comprises a plurality of gradient structures, and the lateral spacing distance between said gradient structures decreases towards said nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area.

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